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Isolation and purification of panarine, A. Alkaloid from a Venezuelan Curare

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Quetin-Leclercq, Joëlle [UCL] Angenot, Luc Dupont, Léon Bisset, Norman G.

High Speed Counter Current Chromatography (HSCCC) has been used to isolate and purify two quaternary alkaloids from a sample of curare prepared by the Panare Indians of Estado Bolivar, Venezuela. One of the compounds is the known base macusine B (1). The other one is a new but related base named panarine (2). Its structure has been established unequivocally by spectral and X-ray crystallographic analysis.

Document type Article de périodique (Journal article) – Article de recherche
Publication date 1988
Language Anglais
Journal information "Phytochemistry" - Vol. 27, no. 12, p. 4002-4004 (1988)
Peer reviewed yes
Publisher Pergamon ((United Kingdom) Kidlington)
issn 0031-9422
e-issn 1873-3700
Publication status Publié
Affiliation UCL - MD/FARM - Ecole de pharmacie
Keywords Quaternary indole alkaloids ; macusine B ; panarine ; HSCCC ; Venezuelan curare ; Panare tribe
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Bibliographic reference Quetin-Leclercq, Joëlle ; Angenot, Luc ; Dupont, Léon ; Bisset, Norman G.. Isolation and purification of panarine, A. Alkaloid from a Venezuelan Curare. In: Phytochemistry, Vol. 27, no. 12, p. 4002-4004 (1988)
Permanent URL http://hdl.handle.net/2078.1/126919