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Dose comparisons of clopidogrel and aspirin in acute coronary syndromes.

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Mehta, Shamir R Bassand, Jean-Pierre Chrolavicius, Susan Diaz, Rafael Dangoisse, Vincent [UCL]

In patients with an acute coronary syndrome who were referred for an invasive strategy, there was no significant difference between a 7-day, double-dose clopidogrel regimen and the standard-dose regimen, or between higher-dose aspirin and lower-dose aspirin, with respect to the primary outcome of cardiovascular death, myocardial infarction, or stroke. (Funded by Sanofi-Aventis and Bristol-Myers Squibb; ClinicalTrials.gov number, NCT00335452.)

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès restreint
Publication date 2010
Language Anglais
Journal information "New England Journal of Medicine" - Vol. 363, no.10, p. 930-42 (2010)
Peer reviewed yes
Publisher Massachusetts Medical Society ((United States) [S.l.])
issn 0028-4793
e-issn 1533-4406
Publication status Publié
Affiliation UCL - (MGD) Service de cardiologie
MESH Subject Acute Coronary Syndrome ; Female ; Hemorrhage ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Myocardial Infarction ; Platelet Aggregation Inhibitors ; Research Design ; Stroke ; Aged ; Ticlopidine ; Angioplasty, Balloon, Coronary ; Aspirin ; Cardiovascular Diseases ; Combined Modality Therapy ; Coronary Angiography ; Coronary Artery Bypass ; Double-Blind Method
Links
Bibliographic reference ; Mehta, Shamir R ; Bassand, Jean-Pierre ; Chrolavicius, Susan ; Diaz, Rafael ; et. al. Dose comparisons of clopidogrel and aspirin in acute coronary syndromes.. In: New England Journal of Medicine, Vol. 363, no.10, p. 930-42 (2010)
Permanent URL http://hdl.handle.net/2078.1/126574