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Effects of riluzole on the evolution of focal cerebral ischemia: a magnetic resonance imaging study.

Bibliographic reference Mottet, I. ; Demeure, R. ; Rataud, J ; Lucas, M. ; Wahl, F ; et. al. Effects of riluzole on the evolution of focal cerebral ischemia: a magnetic resonance imaging study.. In: Magma (New York, N.Y.), Vol. 5, no. 3, p. 185-91 (1997)
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  1. Stutzmann JM, Doble A (1995) Blockade of glutamatergic transmission and neuroprotection: the strange case of riluzole. InNeurodegenerative Diseases (Jolles G, Stutzmann JM, eds.) pp. 205–214. New York: Academic Press.
  2. Malgouris C, Bardot F, Daniel M, Pellis F, Rataud J, Uzan A, Blanchard JC, Laduron P (1989) Riluzole, a novel antiglutamate, prevents memory loss and hippocampal neuronal damage in ischemic gerbils.J Neurosci 9: 3720–3727.
  3. Pratt J, Rataud J, Bardot F, Roux M, Blanchard JC, Laduron P, Stutzmann JM (1992) Neuroprotective actions of riluzole in rodents: models of global and focal cerebral ischemia.Neurosci Lett 140: 225–230.
  4. McIntosh TK, Smith DH, Voddi M, Perri BR, Stutzmann JM (1996) Riluzole, a novel neuroprotective agent, attenuates both neurological motor and cognitive dysfunction following experimental brain injury in the rat.J. Neurotrauma 13: 767–780.
  5. Wahl F, Renou E, Mary V, Stutzmann JM (1997) Riluzole reduces lesions and improves neurological function in rats after a traumatic brain injury.Brain Res. 756: 247–255.
  6. Stutzmann JM, Pratt J, Boraud T, Gross C (1996) The effect of riluzole on post-traumatic spinal cord injury in the rat.Neuroreport 7: 387–392.
  7. Alaoui F, Pratt J, Trocherie S, Court L, Stutzmann JM (1995) Acute effects of irradiation of the rat brain: protection by glutamate blockade.Eur J Pharmacol 276: 55–60.
  8. Benazzouz A, Boraud T, Dubedat P, Boireau A, Stutzmann JM, Gross C (1995) Riluzole prevents MPTP-induced parkinsonism in the rhesus monkey: a pilot study.Eur J Pharmacol 284: 299–307.
  9. Mary F, Wahl F, Stutzmann JM (1995) Effect of riluzole on quinolinate-induced neuronal damage in rats: comparison with blockers of glutamatergic neurotransmission.Neurosci Lett 201: 92–96.
  10. Bensimon G, Lacomblez L, Meininger VA, ALS/Riluzole Study Group (1994) A controlled trial of riluzole in amyotrophic lateral sclerosis.N Engl J Med 330: 585–591.
  11. Hatfield RH, Gill R, Brazell C (1992) The dose-response relationship and therapeutic window for dizocilpine (MK-801) in a rat focal ischemia model.Eur J Pharmacol 216: 1–7.
  12. Siesjö BK (1992) Pathophysiology and treatment of focal cerebral ischemia.J Neurosurg 77: 169–184.
  13. Tamura A., Graham D. I., McCulloch J., Teasdale G. M., Focal Cerebral Ischaemia in the Rat: 1. Description of Technique and Early Neuropathological Consequences following Middle Cerebral Artery Occlusion, 10.1038/jcbfm.1981.6
  14. Paxinos G, Watson C (1982)The Rat Brain in Stereotaxic Coordinates, New York: Academic Press.
  15. Atlas SW, Hackney DB, Listerud J (1993) Fast spin-echo imaging of the brain and spine.Magn Reson Q 9: 61–83.
  16. Haralick RM, Sternberg SR, Zhuang X (1987) Image analysis using mathematical morphology.IEEE Trans Patt Anal Machine Intell 9: 532–549.
  17. Allegrini PR, Sauer D (1992) Application of magnetic resonance imaging to the measurement of neurodegeneration in rat brain: MRI data correlate strongly with histology and enzymatic analysis.Magn Reson Imaging 10: 773–778.
  18. Barone FC, Clark RK, Feuerstein G, Lenkinski RE, Sarkar SK (1991) Quantitative comparison of magnetic resonance imaging (MRI) and histologic analyses of focal ischemic damage in the rat.Brain Res Bull 26: 285–291.
  19. Germano IM, Pitts LH, Berry I, Moseley M (1989) Magnetic resonance imaging and 31P magnetic resonance spectroscopy for evaluating focal cerebral ischemia.J. Neurosurg 70: 612–618.
  20. Seega J, Elger B (1993) Diffusion andT 2-weighted imaging: evaluation of edema reduction in focal cerebral ischemia by calcium and serotonin antagonist levemopamil.Magn Reson Imaging 11: 401–409.
  21. Helpern JA, Dereski MO, Knight RA, Ordidge RJ, Chopp M, Qing ZX (1993) Histopathological correlations of nuclear magnetic resonance imaging parameters in experimental cerebral ischemia.Magn Reson Imaging 11: 241–246.
  22. Knight R. A., Ordidge R. J., Helpern J. A., Chopp M., Rodolosi L. C., Peck D., Temporal evolution of ischemic damage in rat brain measured by proton nuclear magnetic resonance imaging, 10.1161/01.str.22.6.802
  23. Go K. Gwan, Water in Brain Edema : Observations by the Pulsed Nuclear Magnetic Resonance Technique, 10.1001/archneur.1975.00490490066006
  24. Unger E, Littlefield J, Gado M (1988) Water content and water structure in CT and MR signal changes: possible influence in detection of early stroke.AJNR Am J Neuroradiol 9: 687–691.
  25. Rataud J, Debarnot F, Mary V, Pratt J, Stutzmann JM (1994) Comparative study of voltage-sensitive sodium channel blockers in focal ischemia and electric convulsions in rodents.Neurosci Lett 172: 19–23.
  26. Benoît E, Escande D (1991) Riluzole specifically blocks inactivated Na channels in myelinated nerve fibre.Pflugers Arch 419: 603–609.
  27. Doble A, Hubert JP, Blanchard JC (1992) Pertussis toxin pretreatment abolishes the inhibitory effect of riluzole and carbachol ond[3H]-aspartate release from cultured cerebellar granule cells.Neurosci Lett 140: 251–254.
  28. Smith S. E., Meldrum B. S., Cerebroprotective Effect of Lamotrigine After Focal Ischemia in Rats, 10.1161/01.str.26.1.117