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Regulation of muscle glycogen synthase phosphorylation and kinetic properties by insulin, exercise, adrenaline and role in insulin resistance.

Bibliographic reference Jensen, Jørgen ; Lai, Yu-Chiang. Regulation of muscle glycogen synthase phosphorylation and kinetic properties by insulin, exercise, adrenaline and role in insulin resistance.. In: Archives of Physiology and Biochemistry : the journal of metabolic diseases, Vol. 115, no.1, p. 13-21 (2009)
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  1. Aas V., Kase E.T., Solberg R., Jensen J., Rustan A.C., Chronic hyperglycaemia promotes lipogenesis and triacylglycerol accumulation in human skeletal muscle cells, 10.1007/s00125-004-1465-9
  2. Acheson KJ, Am J Clin Nutr, 48, 240 (1988)
  3. Aschenbach William G., Suzuki Yoichi, Breeden Kristine, Prats Clara, Hirshman Michael F., Dufresne Scott D., Sakamoto Kei, Vilardo Pier Giuseppe, Steele Marcella, Kim Jong-Hwa, Jing Shao-liang, Goodyear Laurie J., DePaoli-Roach Anna A., The Muscle-specific Protein Phosphatase PP1G/RGL(GM) Is Essential for Activation of Glycogen Synthase by Exercise, 10.1074/jbc.m105518200
  4. Aslesen R, J Appl Physiol, 91, 1237 (2001)
  5. Aslesen R, Am J Physiol, 275, E448 (1998)
  6. Beck-Nielsen Henning, Vaag Allan, Poulsen Pernille, Gaster Michael, Metabolic and genetic influence on glucose metabolism in type 2 diabetic subjects—experiences from relatives and twin studies, 10.1016/s1521-690x(03)00041-1
  7. Bouskila M., Hirshman M. F., Jensen J., Goodyear L. J., Sakamoto K., Insulin promotes glycogen synthesis in the absence of GSK3 phosphorylation in skeletal muscle, 10.1152/ajpendo.00481.2007
  8. Burén J., Lai Y.C., Lundgren M., Eriksson J.W., Jensen J., Insulin action and signalling in fat and muscle from dexamethasone-treated rats, 10.1016/
  9. Carling David, Grahame Hardie D., The substrate and sequence specificity of the AMP-activated protein kinase. Phosphorylation of glycogen synthase and phosphorylase kinase, 10.1016/0167-4889(89)90014-1
  10. Cohen Philip, Dissection of the Protein Phosphorylation Cascades Involved in Insulin and Growth Factor Action, 10.1042/bst0210555
  11. Cohen P., The Croonian Lecture 1998. Identification of a protein kinase cascade of major importance in insulin signal transduction, 10.1098/rstb.1999.0399
  12. Cohen PT, J Cell Sci, 115, 241 (2002)
  13. Copeland R. J., Bullen J. W., Hart G. W., Cross-talk between GlcNAcylation and phosphorylation: roles in insulin resistance and glucose toxicity, 10.1152/ajpendo.90281.2008
  14. Danforth WH, J Biol Chem, 240, 588 (1965)
  15. DeFronzo R A, Gunnarsson R, Björkman O, Olsson M, Wahren J, Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus., 10.1172/jci111938
  16. FRANCH Jesper, ASLESEN Rune, JENSEN Jørgen, Regulation of glycogen synthesis in rat skeletal muscle after glycogen-depleting contractile activity: effects of adrenaline on glycogen synthesis and activation of glycogen synthase and glycogen phosphorylase, 10.1042/0264-6021:3440231
  17. Franch J., Knudsen J., Ellis B. A., Pedersen P. K., Cooney G. J., Jensen J., Acyl-CoA Binding Protein Expression Is Fiber Type- Specific and Elevated in Muscles From the Obese Insulin-Resistant Zucker Rat, 10.2337/diabetes.51.2.449
  18. Friedman Daniel L., Larner Joseph, Studies on UDPG-α-Glucan Transglucosylase. III. Interconversion of Two Forms of Muscle UDPG-α-Glucan Transglucosylase by a Phosphorylation-Dephosphorylation Reaction Sequence*, 10.1021/bi00904a009
  19. Hojlund K., Staehr P., Hansen B. F., Green K. A., Hardie D. G., Richter E. A., Beck-Nielsen H., Wojtaszewski J. F.P., Increased Phosphorylation of Skeletal Muscle Glycogen Synthase at NH2-Terminal Sites During Physiological Hyperinsulinemia in Type 2 Diabetes, 10.2337/diabetes.52.6.1393
  20. Jensen J, Biochem Mol Biol Int, 35, 145 (1995)
  21. Jensen Jørgen, Grønning-Wang Line M., Jebens Einar, Whitehead Jonathan P., Zorec Robert, Shepherd Peter R., Adrenaline potentiates insulin-stimulated PKB activation in the rat fast-twitch epitrochlearis muscle without affecting IRS-1-associated PI 3-kinase activity, 10.1007/s00424-008-0471-z
  22. Jensen J., Muscle glycogen inharmoniously regulates glycogen synthase activity, glucose uptake, and proximal insulin signaling, 10.1152/ajpendo.00330.2005
  23. Jensen J., Ruzzin J., Jebens E., Brennesvik E. O., Knardahl S., Improved insulin-stimulated glucose uptake and glycogen synthase activation in rat skeletal muscles after adrenaline infusion: role of glycogen content and PKB phosphorylation, 10.1111/j.1365-201x.2005.01437.x
  24. Jorgensen S. B., Nielsen J. N., Birk J. B., Olsen G. S., Viollet B., Andreelli F., Schjerling P., Vaulont S., Hardie D. G., Hansen B. F., Richter E. A., Wojtaszewski J. F.P., The  2-5'AMP-Activated Protein Kinase Is a Site 2 Glycogen Synthase Kinase in Skeletal Muscle and Is Responsive to Glucose Loading, 10.2337/diabetes.53.12.3074
  25. Kochan RG, Am J Physiol, 240, E197 (1981)
  26. Komuniecki P. R., Kochan R. G., Schlender K. K., Reimann E. M., Glycogen synthase in diabetic rat skeletal muscle: activation by insulin, 10.1007/bf00421224
  27. KUMA Yvonne, CAMPBELL David G., CUENDA Ana, Identification of glycogen synthase as a new substrate for stress-activated protein kinase 2b/p38beta, 10.1042/bj20031559
  28. Lai Y.-C., Stuenaes J. T., Kuo C.-H., Jensen J., Glycogen content and contraction regulate glycogen synthase phosphorylation and affinity for UDP-glucose in rat skeletal muscles, 10.1152/ajpendo.00113.2007
  29. Leloir L. F., Cardini C. E., BIOSYNTHESIS OF GLYCOGEN FROM URIDINE DIPHOSPHATE GLUCOSE1, 10.1021/ja01580a061
  30. Leloir L.F., Olavarría J.M., Goldemberg Sara H., Carminatti H., Biosynthesis of glycogen from uridine diphosphate glucose, 10.1016/0003-9861(59)90232-2
  31. Mæhlum S., Høstmark A. T., Hermansen L., Synthesis of muscle glycogen during recovery after prolonged severe exercise in diabetic subjects. Effect of insulin deprivation, 10.3109/00365517809108400
  32. McManus Edward J, Sakamoto Kei, Armit Laura J, Ronaldson Leah, Shpiro Natalia, Marquez Rodolfo, Alessi Dario R, Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis, 10.1038/sj.emboj.7600633
  33. Nielsen Jakob Nis, Derave Wim, Kristiansen Søren, Ralston Evelyn, Ploug Thorkil, Richter Erik A., Glycogen synthase localization and activity in rat skeletal muscle is strongly dependent on glycogen content, 10.1111/j.1469-7793.2001.0757h.x
  34. PARKER Peter J., CAUDWELL F. Barry, COHEN Philip, Glycogen Synthase from Rabbit Skeletal Muscle; Effect of Insulin on the State of phosphorylation of the Seven Phosphoserine Residues in vivo, 10.1111/j.1432-1033.1983.tb07140.x
  35. Piras Romano, Staneloni Roberto, In vivo regulation of rat muscle glycogen synthetase activity, 10.1021/bi00833a056
  36. Prats Clara, Cadefau Joan A., Cussó Roser, Qvortrup Klaus, Nielsen Jakob N., Wojtaszewki Jørgen F. P., Hardie D. Grahame, Stewart Greg, Hansen Bo F., Ploug Thorkil, Phosphorylation-dependent Translocation of Glycogen Synthase to a Novel Structure during Glycogen Resynthesis, 10.1074/jbc.m502713200
  37. Reynolds Thomas H., Pak Yunbae, Harris Thurl E., Manchester Jill, Barrett Eugene J., Lawrence John C., Effects of Insulin and Transgenic Overexpression of UDP-glucose Pyrophosphorylase on UDP-glucose and Glycogen Accumulation in Skeletal Muscle Fibers, 10.1074/jbc.m413614200
  38. Richter Erik A., Derave Wim, Wojtaszewski Jørgen F. P., Glucose, exercise and insulin: emerging concepts, 10.1111/j.1469-7793.2001.t01-2-00313.x
  39. Richter Erik A., Garetto Lawrence P., Goodman Michael N., Ruderman Neil B., Muscle Glucose Metabolism following Exercise in the Rat, 10.1172/jci110517
  40. Roach PJ, FASEB J, 4, 2961 (1990)
  41. Roach PJ, J Biol Chem, 251, 1913 (1976)
  42. Rossetti L, Hu M, Skeletal muscle glycogenolysis is more sensitive to insulin than is glucose transport/phosphorylation. Relation to the insulin-mediated inhibition of hepatic glucose production., 10.1172/jci116919
  43. Rothman D L, Shulman R G, Shulman G I, 31P nuclear magnetic resonance measurements of muscle glucose-6-phosphate. Evidence for reduced insulin-dependent muscle glucose transport or phosphorylation activity in non-insulin-dependent diabetes mellitus., 10.1172/jci115686
  44. Ruzzin J., Wagman A. S., Jensen J., Glucocorticoid-induced insulin resistance in skeletal muscles: defects in insulin signalling and the effects of a selective glycogen synthase kinase-3 inhibitor, 10.1007/s00125-005-1886-0
  45. Sacchetto Roberta, Bovo Elisa, Salviati Leonardo, Damiani Ernesto, Margreth Alfredo, Glycogen synthase binds to sarcoplasmic reticulum and is phosphorylated by CaMKII in fast-twitch skeletal muscle, 10.1016/
  46. Shulman Gerald I., Rothman Douglas L., Jue Thomas, Stein Peter, DeFronzo Ralph A., Shulman Robert G., Quantitation of Muscle Glycogen Synthesis in Normal Subjects and Subjects with Non-Insulin-Dependent Diabetes by13C Nuclear Magnetic Resonance Spectroscopy, 10.1056/nejm199001253220403
  47. Skurat Alexander V., Dietrich Amy D., Phosphorylation of Ser640in Muscle Glycogen Synthase by DYRK Family Protein Kinases, 10.1074/jbc.m301769200
  48. Skurat A. V., Dietrich A. D., Roach P. J., Glycogen synthase sensitivity to insulin and glucose-6-phosphate is mediated by both NH2- and COOH-terminal phosphorylation sites, 10.2337/diabetes.49.7.1096
  49. Skurat Alexander V., Roach Peter J., Phosphorylation of Sites 3a and 3b (Ser640and Ser644) in the Control of Rabbit Muscle Glycogen Synthase, 10.1074/jbc.270.21.12491
  50. Taylor R, Magnusson I, Rothman D L, Cline G W, Caumo A, Cobelli C, Shulman G I, Direct assessment of liver glycogen storage by 13C nuclear magnetic resonance spectroscopy and regulation of glucose homeostasis after a mixed meal in normal subjects., 10.1172/jci118379
  51. Taylor R, Am J Physiol, 265, E224 (1993)
  52. Toole Barry J., Cohen Patricia T.W., The skeletal muscle-specific glycogen-targeted protein phosphatase 1 plays a major role in the regulation of glycogen metabolism by adrenaline in vivo, 10.1016/j.cellsig.2006.11.013
  53. Villar-Palasí Carlos, Larner Joseph, Insulin-mediated effect on the activity of UDPG-glycogen transglucosylase of muscle, 10.1016/0006-3002(60)90142-6
  54. Wilson W. A., Skurat A. V., Probst B., de Paoli-Roach A., Roach P. J., Rutter J., Control of mammalian glycogen synthase by PAS kinase, 10.1073/pnas.0508481102