User menu

Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase.

Bibliographic reference Pilotte, Luc ; Larrieu, Pierre ; Stroobant, Vincent ; Colau, Didier ; Dolusic, Eduard ; et. al. Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase.. In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, no. 7, p. 2497-2502 (2012)
Permanent URL http://hdl.handle.net/2078/121066
  1. Munn David H., Shafizadeh Ebrahim, Attwood John T., Bondarev Igor, Pashine Achal, Mellor Andrew L., Inhibition of  T Cell Proliferation by Macrophage Tryptophan Catabolism, 10.1084/jem.189.9.1363
  2. Munn D. H., Prevention of Allogeneic Fetal Rejection by Tryptophan Catabolism, 10.1126/science.281.5380.1191
  3. Terness Peter, Bauer Thomas M., Röse Lars, Dufter Christoph, Watzlik Andrea, Simon Helmut, Opelz Gerhard, Inhibition of Allogeneic T Cell Proliferation by Indoleamine 2,3-Dioxygenase–expressing Dendritic Cells : Mediation of Suppression by Tryptophan Metabolites, 10.1084/jem.20020052
  4. Uyttenhove Catherine, Pilotte Luc, Théate Ivan, Stroobant Vincent, Colau Didier, Parmentier Nicolas, Boon Thierry, Van den Eynde Benoît J, Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase, 10.1038/nm934
  5. Muller Alexander J, DuHadaway James B, Donover P Scott, Sutanto-Ward Erika, Prendergast George C, Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy, 10.1038/nm1196
  6. Munn David H., Mellor Andrew L., Indoleamine 2,3-dioxygenase and tumor-induced tolerance, 10.1172/jci31178
  7. Löb Stefan, Königsrainer Alfred, Rammensee Hans-Georg, Opelz Gerhard, Terness Peter, Inhibitors of indoleamine-2,3-dioxygenase for cancer therapy: can we see the wood for the trees?, 10.1038/nrc2639
  8. Grohmann Ursula, Bronte Vincenzo, Control of immune response by amino acid metabolism : Metabolic regulation of immune responses, 10.1111/j.1600-065x.2010.00915.x
  9. Schmidt Silvia K., Müller Anika, Heseler Kathrin, Woite Claudia, Spekker Katrin, MacKenzie Colin R., Däubener Walter, Antimicrobial and immunoregulatory properties of human tryptophan 2,3-dioxygenase, 10.1002/eji.200939535
  10. Salter Mark, Hazelwood Robert, Pogson Christopher I., Iyer Ramachandran, Madge David J., The effects of a novel and selective inhibitor of tryptophan 2,3-dioxygenase on tryptophan and serotonin metabolism in the rat, 10.1016/0006-2952(95)00006-l
  11. Van den Eynde B., The gene coding for a major tumor rejection antigen of tumor P815 is identical to the normal gene of syngeneic DBA/2 mice, 10.1084/jem.173.6.1373
  12. Brändle Daniel, Bilsborough Janine, Rülicke Thomas, Uyttenhove Catherine, Boon Thierry, Van den Eynde Benoît J., The shared tumor-specific antigen encoded by mouse geneP1A is a target not only for cytolytic T lymphocytes but also for tumor rejection, 10.1002/(sici)1521-4141(199812)28:12<4010::aid-immu4010>3.0.co;2-5
  13. Civen, Journal of Biological Chemistry, 235, 1716 (1960)
  14. Eguchi Naomi, Watanabe Yasuyoshi, Kawanishi Kazuko, Hashimoto Yohei, Hayaishi Osamu, Inhibition of indoleamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase by β-carboline and indole derivatives, 10.1016/0003-9861(84)90579-4
  15. Frieden Earl, Westmark G.Wayne, Schor Joseph M., Inhibition of tryptophan pyrrolase by serotonin, epinephrine and tryptophan analogs, 10.1016/0003-9861(61)90233-8
  16. Dolušić Eduard, Larrieu Pierre, Moineaux Laurence, Stroobant Vincent, Pilotte Luc, Colau Didier, Pochet Lionel, Van den Eynde Benoît, Masereel Bernard, Wouters Johan, Frédérick Raphaël, Tryptophan 2,3-Dioxygenase (TDO) Inhibitors. 3-(2-(Pyridyl)ethenyl)indoles as Potential Anticancer Immunomodulators, 10.1021/jm2006782
  17. Widner, Clinical Chemistry, 43, 2424 (1997)
  18. REN QUN, ROBERTSON SHELLY J., HOWE DALE, BARROWS LORRAINE F., HEINZEN ROBERT A., Comparative DNA Microarray Analysis of Host Cell Transcriptional Responses to Infection byCoxiella burnetiiorChlamydia trachomatis, 10.1111/j.1749-6632.2003.tb07447.x
  19. Kohro Takahide, Tanaka Toshiya, Murakami Takeshi, Wada Yoichiro, Aburatani Hiroyuki, Hamakubo Takao, Kodama Tatsuhiko, A Comparison of Differences in the Gene Expression Profiles of Phorbol 12-myristate 13-acetate Differentiated THP-1 Cells and Human Monocyte-derived Macrophage, 10.5551/jat.11.88
  20. Hodi F. Stephen, O'Day Steven J., McDermott David F., Weber Robert W., Sosman Jeffrey A., Haanen John B., Gonzalez Rene, Robert Caroline, Schadendorf Dirk, Hassel Jessica C., Akerley Wallace, van den Eertwegh Alfons J.M., Lutzky Jose, Lorigan Paul, Vaubel Julia M., Linette Gerald P., Hogg David, Ottensmeier Christian H., Lebbé Celeste, Peschel Christian, Quirt Ian, Clark Joseph I., Wolchok Jedd D., Weber Jeffrey S., Tian Jason, Yellin Michael J., Nichol Geoffrey M., Hoos Axel, Urba Walter J., Improved Survival with Ipilimumab in Patients with Metastatic Melanoma, 10.1056/nejmoa1003466
  21. Hwu Patrick, Treating Cancer by Targeting the Immune System, 10.1056/nejme1006416
  22. Longo Dan L., New Therapies for Castration-Resistant Prostate Cancer, 10.1056/nejme1006300
  23. Kantoff Philip W., Higano Celestia S., Shore Neal D., Berger E. Roy, Small Eric J., Penson David F., Redfern Charles H., Ferrari Anna C., Dreicer Robert, Sims Robert B., Xu Yi, Frohlich Mark W., Schellhammer Paul F., Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer, 10.1056/nejmoa1001294
  24. Higano Celestia S., Small Eric J., Schellhammer Paul, Yasothan Uma, Gubernick Steven, Kirkpatrick Peter, Kantoff Philip W., Sipuleucel-T, 10.1038/nrd3220
  25. Robert Caroline, Thomas Luc, Bondarenko Igor, O'Day Steven, Weber Jeffrey, Garbe Claus, Lebbe Celeste, Baurain Jean-François, Testori Alessandro, Grob Jean-Jacques, Davidson Neville, Richards Jon, Maio Michele, Hauschild Axel, Miller Wilson H., Gascon Pere, Lotem Michal, Harmankaya Kaan, Ibrahim Ramy, Francis Stephen, Chen Tai-Tsang, Humphrey Rachel, Hoos Axel, Wolchok Jedd D., Ipilimumab plus Dacarbazine for Previously Untreated Metastatic Melanoma, 10.1056/nejmoa1104621
  26. Ledford Heidi, Melanoma drug wins US approval, 10.1038/471561a
  27. Boon Thierry, Coulie Pierre G., Eynde Benoît J. Van den, Bruggen Pierre van der, HUMAN T CELL RESPONSES AGAINST MELANOMA, 10.1146/annurev.immunol.24.021605.090733
  28. Röhrig Ute F., Awad Loay, Grosdidier Aurélien, Larrieu Pierre, Stroobant Vincent, Colau Didier, Cerundolo Vincenzo, Simpson Andrew J. G., Vogel Pierre, Van den Eynde Benoît J., Zoete Vincent, Michielin Olivier, Rational Design of Indoleamine 2,3-Dioxygenase Inhibitors, 10.1021/jm9014718
  29. Yue Eddy W., Douty Brent, Wayland Brian, Bower Michael, Liu Xiangdong, Leffet Lynn, Wang Qian, Bowman Kevin J., Hansbury Michael J., Liu Changnian, Wei Min, Li Yanlong, Wynn Richard, Burn Timothy C., Koblish Holly K., Fridman Jordan S., Metcalf Brian, Scherle Peggy A., Combs Andrew P., Discovery of Potent Competitive Inhibitors of Indoleamine 2,3-Dioxygenase with in Vivo Pharmacodynamic Activity and Efficacy in a Mouse Melanoma Model, 10.1021/jm900518f
  30. Katz Jessica B., Muller Alexander J., Prendergast George C., Indoleamine 2,3-dioxygenase in T-cell tolerance and tumoral immune escape, 10.1111/j.1600-065x.2008.00610.x
  31. Minatogawa Yohsuke, Suzuki Sachiko, Ando Yoko, Tone Shigenobu, Takikawa Osamu, Tryptophan Pyrrole Ring Cleavage Enzymes in Placenta, Advances in Experimental Medicine and Biology (2003) ISBN:9781461349396 p.425-434, 10.1007/978-1-4615-0135-0_50
  32. SUZUKI Sachiko, TONÉ Shigenobu, TAKIKAWA Osamu, KUBO Toshikazu, KOHNO Ichiro, MINATOGAWA Yohsuke, Expression of indoleamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase in early concepti, 10.1042/0264-6021:3550425
  33. Tatsumi Keiji, Higuchi Toshihiro, Fujiwara Hiroshi, Nakayama Takahiro, Egawa Haruto, Itoh Katsuhiko, Fujii Shingo, Fujita Jun, Induction of Tryptophan 2,3-Dioxygenase in the Mouse Endometrium during Implantation, 10.1006/bbrc.2000.3115
  34. Miller Christine L, Llenos Ida C, Dulay Jeanette R, Barillo Meliza M, Yolken Robert H, Weis Serge, Expression of the kynurenine pathway enzyme tryptophan 2,3-dioxygenase is increased in the frontal cortex of individuals with schizophrenia, 10.1016/j.nbd.2003.12.015
  35. Kanai Masaaki, Funakoshi Hiroshi, Takahashi Hisaaki, Hayakawa Tomoko, Mizuno Shinya, Matsumoto Kunio, Nakamura Toshikazu, Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice, 10.1186/1756-6606-2-8
  36. Opitz Christiane A., Litzenburger Ulrike M., Sahm Felix, Ott Martina, Tritschler Isabel, Trump Saskia, Schumacher Theresa, Jestaedt Leonie, Schrenk Dieter, Weller Michael, Jugold Manfred, Guillemin Gilles J., Miller Christine L., Lutz Christian, Radlwimmer Bernhard, Lehmann Irina, von Deimling Andreas, Wick Wolfgang, Platten Michael, An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor, 10.1038/nature10491