User menu

Influence of repeated administration of cimetidine on the pharmacokinetics and pharmacodynamics of adinazolam in healthy subjects.

Bibliographic reference Hulhoven, R. ; Desager, Jean-Pierre ; Cox, S ; Harvengt, C.. Influence of repeated administration of cimetidine on the pharmacokinetics and pharmacodynamics of adinazolam in healthy subjects.. In: European journal of clinical pharmacology, Vol. 35, no. 1, p. 59-64 (1988)
Permanent URL
  1. Lahti RA, Sethy VH, Barsuhn C, Hester JB (1983) Pharmacological profile of the antidepressant adinazolam, a triazolobenzodiazepine. Neuropharmacology 22: 1277?1282
  2. Turmel A, De Montigny C (1984) Sensitization of rat forebrain neurons to serotonin by adinazolam, an antidepressant triazolobenzodiazepine. Eur J Pharmacol 99: 241?244
  3. Sethy VA, Collins RJ, Daniels DG (1984) Determination of biological activity of adinazolam and its metabolites. J Pharm Pharmacol 36: 546?548
  4. Pyke RE, Cohn JB, Feighner JP, Smith WT (1983) Open-label studies of adinazolam in severe depression. Psychopharmacology Bull 19: 96?98
  5. Smith WT, Glaudin V (1986) Double-blind efficacy and safety study comparing adinazolam mesylate and placebo in depressed inpatients. Acta Psychiatr Scand 74: 238?245
  6. Amsterdam JD, Kaplan M, Potter L, Bloom L, Rickels K (1986) Adinazolam, a new triazolobenzodiazepine, and imipramine in the treatment of major depressive disorder. Psychopharmacology 88: 484?488
  7. Somogyi A, Muirhead M (1987) Pharmacokinetic interactions of cimetidine 1987. Clin Pharmacokinet 12: 321?366
  8. Descotes J, Simonet R, Loupi E, Evreux JC (1986) Interactions medicamenteuses par inhibition enzymatique. Therapie 41: 349?351
  9. Pourbaix S, Desager JP, Hulhoven R, Smith RB, Harvengt C (1985) Pharmacokinetic consequences of long-term coadministration of cimetidine and triazolobenzodiazepines, alprazolam and triazolam, in healthy subjects. Int J Clin Pharmacol Ther Toxicol 23: 447?451
  10. Levine J (1985) Safety rating system, US Health Department (as modified by Upjohn, Kalamazoo, USA)
  11. Clyde DJ (1963) Manual for the Clyde Mood scale. Clyde Computing Service, Miami
  12. Wechsler (1955) A manual for the Wechsler adult intelligence scale. Psychological Corporation, New York
  13. Jensen AR, Thower WD (1966) The Stroop color-word test: A review. Acta Psychologica 25: 36?93
  14. Peng GW (1984) Assay of adinazolam in plasma by liquid chromatography. J Pharm Sci 73: 1173?1175
  15. Desager JP (1986) Applicability of disposable extraction columns to CNS-drug analysis. In: Reid E, Scales B, Wilson ID (eds) Bioactive analytes, including CNS drugs, peptides and enantiomers. Plenum, New York
  16. Mihaly GW, Cockbain S, Jones DB, Hanson RG, Smallwood RA (1982) High-pressure liquid chromatographic determination of cimetidine in plasma and urine. J Pharm Sci 71: 590?592
  17. SAS User Guide, Basics and statistics, version 5, SAS Institute Inc., Box 8000, Cary, NC
  18. Sethy VH, Francis JW, Day JS (1986) The effect of proadifen on the metabolism of adinazolam. J Pharm Pharmacol 38: 631?632