User menu

Calcium-mediated transient phosphorylation of tau and amyloid precursor protein followed by intraneuronal amyloid-beta accumulation.

Bibliographic reference Pierrot, Nathalie ; Santos, Susana Ferrao ; Feyt, Christine ; Morel, Marina ; Brion, Jean-Pierre ; et. al. Calcium-mediated transient phosphorylation of tau and amyloid precursor protein followed by intraneuronal amyloid-beta accumulation.. In: The Journal of biological chemistry, Vol. 281, no. 52, p. 39907-14 (2006)
Permanent URL
  1. Braak H., Braak E., Neuropathological stageing of Alzheimer-related changes, 10.1007/bf00308809
  2. Price Joseph L., Morris John C., Tangles and plaques in nondemented aging and ?preclinical? Alzheimer's disease, 10.1002/1531-8249(199903)45:3<358::aid-ana12>;2-x
  3. Takashima A., Noguchi K., Sato K., Hoshino T., Imahori K., Tau protein kinase I is essential for amyloid beta-protein-induced neurotoxicity., 10.1073/pnas.90.16.7789
  4. Kienlen-Campard Pascal, Miolet Sarah, Tasiaux Bernadette, Octave Jean-Noël, Intracellular Amyloid-β1–42, but Not Extracellular Soluble Amyloid-β Peptides, Induces Neuronal Apoptosis, 10.1074/jbc.m200887200
  5. Pierrot Nathalie, Ghisdal Philippe, Caumont Anne-Sophie, Octave Jean-Noël, Intraneuronal amyloid-β1-42 production triggered by sustained increase of cytosolic calcium concentration induces neuronal death : Calcium increase and intraneuronal Aβ1-42 production, 10.1046/j.1471-4159.2003.02227.x
  6. Macq Anne-Françoise, Czech Christian, Essalmani Rachid, Brion Jean-Pierre, Maron Anne, Mercken Luc, Pradier Laurent, Octave Jean-Noël, The Long Term Adenoviral Expression of the Human Amyloid Precursor Protein Shows Different Secretase Activities in Rat Cortical Neurons and Astrocytes, 10.1074/jbc.273.44.28931
  7. Brewer G. J., Serum-free B27/neurobasal medium supports differentiated growth of neurons from the striatum, substantia nigra, septum, cerebral cortex, cerebellum, and dentate gyrus, 10.1002/jnr.490420510
  8. Lemarchand P., Jaffe H. A., Danel C., Cid M. C., Kleinman H. K., Stratford-Perricaudet L. D., Perricaudet M., Pavirani A., Lecocq J. P., Crystal R. G., Adenovirus-mediated transfer of a recombinant human alpha 1-antitrypsin cDNA to human endothelial cells., 10.1073/pnas.89.14.6482
  9. Biochem. J., 273, 127 (1991)
  10. Otvos L., Feiner L., Lang E., Szendrei G. I., Goedert M., Lee V. M-Y., Monoclonal antibody PHF-1 recognizes tau protein phosphorylated at serine residues 396 and 404, 10.1002/jnr.490390607
  11. Sergeant Nicolas, David Jean-Philippe, Champain Danie, Ghestem Antoine, Wattez Annick, Delacourte André, Progressive decrease of amyloid precursor protein carboxy terminal fragments (APP-CTFs), associated with tau pathology stages, in Alzheimer's disease : Loss of APP-CTFs linked to tau pathology in AD, 10.1046/j.1471-4159.2002.00901.x
  12. J. Submicrosc. Cytol., 17, 89 (1985)
  13. Skovronsky Daniel M., Doms Robert W., Lee Virginia M.-Y., Detection of a Novel Intraneuronal Pool of Insoluble Amyloid β Protein that Accumulates with Time in Culture, 10.1083/jcb.141.4.1031
  14. Gong Cheng-Xin, Singh Toolsee J., Grundke-Iqbal Inge, Iqbal Khalid, Phosphoprotein Phosphatase Activities in Alzheimer Disease Brain, 10.1111/j.1471-4159.1993.tb03603.x
  15. J. Biochem. (Tokyo), 121, 179 (1997)
  16. Hartigan Judith A., Johnson Gail V. W., Transient Increases in Intracellular Calcium Result in Prolonged Site-selective Increases in Tau Phosphorylation through a Glycogen Synthase Kinase 3β-dependent Pathway, 10.1074/jbc.274.30.21395
  17. Phiel Christopher J., Wilson Christina A., Lee Virginia M.-Y., Klein Peter S., GSK-3α regulates production of Alzheimer's disease amyloid-β peptides, 10.1038/nature01640
  18. Ryder John, Su Yuan, Liu Feng, Li Baolin, Zhou Yan, Ni Binhui, Divergent roles of GSK3 and CDK5 in APP processing, 10.1016/j.bbrc.2003.11.014
  19. J. Neurochem., 67, 699 (1996)
  20. Liu Feng, Su Yuan, Li Baolin, Zhou Yan, Ryder John, Gonzalez-DeWhitt Patricia, May Patrick C, Ni Binhui, Regulation of amyloid precursor protein (APP) phosphorylation and processing by p35/Cdk5 and p25/Cdk5, 10.1016/s0014-5793(03)00714-2
  21. Kerokoski Petri, Suuronen Tiina, Salminen Antero, Soininen Hilkka, Pirttilä Tuula, Both N-methyl-d-aspartate (NMDA) and non-NMDA receptors mediate glutamate-induced cleavage of the cyclin-dependent kinase 5 (cdk5) activator p35 in cultured rat hippocampal neurons, 10.1016/j.neulet.2004.07.007
  22. Meijer Laurent, Borgne Annie, Mulner Odile, Chong James P. J., Blow J. Julian, Inagaki Naoyuki, Inagaki Masaki, Delcros Jean-Guy, Moulinoux Jacques-Philippe, Biochemical and Cellular Effects of Roscovitine, a Potent and Selective Inhibitor of the Cyclin-Dependent Kinases cdc2, cdk2 and cdk5, 10.1111/j.1432-1033.1997.t01-2-00527.x
  23. Glenner George G., Wong Caine W., Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein, 10.1016/s0006-291x(84)80190-4
  24. Coghlan Matthew P, Culbert Ainsley A, Cross Darren AE, Corcoran Stacey L, Yates John W, Pearce Nigel J, Rausch Oliver L, Murphy Gregory J, Carter Paul S, Roxbee Cox Lynne, Mills David, Brown Murray J, Haigh David, Ward Robert W, Smith David G, Murray Kenneth J, Reith Alastair D, Holder Julie C, Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription, 10.1016/s1074-5521(00)00025-9
  25. Collins Frank, Lile Jack D., The role of dihydropyridine-sensitive voltage-gated calcium channels in potassium-mediated neuronal survival, 10.1016/0006-8993(89)90465-4
  26. Zhang Yan, McLaughlin Richard, Goodyer Cynthia, LeBlanc Andréa, Selective cytotoxicity of intracellular amyloid β peptide1–42through p53 and Bax in cultured primary human neurons, 10.1083/jcb.200110119
  27. Bennett David A., Schneider Julie A., Wilson Robert S., Bienias Julia L., Arnold Steven E., Neurofibrillary Tangles Mediate the Association of Amyloid Load With Clinical Alzheimer Disease and Level of Cognitive Function, 10.1001/archneur.61.3.378
  28. Boutajangout Allal, Authelet Michèle, Blanchard Véronique, Touchet N, Tremp Gunter, Pradier Laurent, Brion Jean-Pierre, Characterisation of cytoskeletal abnormalities in mice transgenic for wild-type human tau and familial Alzheimer's disease mutants of APP and presenilin-1, 10.1016/j.nbd.2003.09.007
  29. Oddo S, Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease, 10.1016/j.neurobiolaging.2003.08.012
  30. Walsh Dominic M., Hartley Dean M., Kusumoto Yoko, Fezoui Youcef, Condron Margaret M., Lomakin Aleksey, Benedek George B., Selkoe Dennis J., Teplow David B., Amyloid β-Protein Fibrillogenesis : STRUCTURE AND BIOLOGICAL ACTIVITY OF PROTOFIBRILLAR INTERMEDIATES, 10.1074/jbc.274.36.25945
  31. Walsh D. M., Klyubin I., Fadeeva J. V., Rowan M. J., Selkoe D. J., Amyloid-β oligomers: their production, toxicity and therapeutic inhibition, 10.1042/bst0300552
  32. Sato Takeshi, Kienlen-Campard Pascal, Ahmed Mahiuddin, Liu Wei, Li Huilin, Elliott James I., Aimoto Saburo, Constantinescu Stefan N., Octave Jean-Noel, Smith Steven O., Inhibitors of Amyloid Toxicity Based on β-sheet Packing of Aβ40 and Aβ42†, 10.1021/bi052485f
  33. Masters C. L., Simms G., Weinman N. A., Multhaup G., McDonald B. L., Beyreuther K., Amyloid plaque core protein in Alzheimer disease and Down syndrome., 10.1073/pnas.82.12.4245
  34. Walsh Dominic M., Tseng Bertrand P., Rydel Russell E., Podlisny Marcia B., Selkoe Dennis J., The Oligomerization of Amyloid β-Protein Begins Intracellularly in Cells Derived from Human Brain†, 10.1021/bi001048s
  35. Klein W, Targeting small Aβ oligomers: the solution to an Alzheimer's disease conundrum?, 10.1016/s0166-2236(00)01749-5
  36. Iijima Ko-ichi, Ando Kanae, Takeda Shizu, Satoh Yasushi, Seki Tatsunori, Itohara Shigeyoshi, Greengard Paul, Kirino Yutaka, Nairn Angus C., Suzuki Toshiharu, Neuron-Specific Phosphorylation of Alzheimer's β-Amyloid Precursor Protein by Cyclin-Dependent Kinase 5, 10.1046/j.1471-4159.2000.0751085.x
  37. Ahlijanian M. K., Barrezueta N. X., Williams R. D., Jakowski A., Kowsz K. P., McCarthy S., Coskran T., Carlo A., Seymour P. A., Burkhardt J. E., Nelson R. B., McNeish J. D., Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5, 10.1073/pnas.040577797
  38. Hanger Diane P., Hughes Kenneth, Woodgett James R., Brion Jean-Pierre, Anderton Brian H., Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: Generation of paired helical filament epitopes and neuronal localisation of the kinase, 10.1016/0304-3940(92)90774-2
  39. Shea Thomas B., Ekinci Fatma J., Biphasic Effect of Calcium Influx on Tau Phosphorylation: Involvement of Calcium-Dependent Phosphatase and Kinase Activities, 10.3233/jad-1999-1601
  40. Paglini Gabriela, Cáceres Alfredo, The role of the Cdk5-p35 kinase in neuronal development : Cdk5-p35 function in developing neurons, 10.1046/j.1432-1327.2001.02023.x
  41. Lee Ming-sum, Kwon Young T., Li Mingwei, Peng Junmin, Friedlander Robert M., Tsai Li-Huei, 10.1038/35012636
  42. Lew John, Huang Qi-Quan, Qi Zhong, Winkfein Robert J., Aebersold Ruedi, Hunt Tim, Wang Jerry H., A brain-specific activator of cyclin-dependent kinase 5, 10.1038/371423a0
  43. Cruz Jonathan C., Tseng Huang-Chun, Goldman Joseph A., Shih Heather, Tsai Li-Huei, Aberrant Cdk5 Activation by p25 Triggers Pathological Events Leading to Neurodegeneration and Neurofibrillary Tangles, 10.1016/s0896-6273(03)00627-5
  44. Kang Jie, Lemaire Hans-Georg, Unterbeck Axel, Salbaum J. Michael, Masters Colin L., Grzeschik Karl-Heinz, Multhaup Gerd, Beyreuther Konrad, Müller-Hill Benno, The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor, 10.1038/325733a0
  45. Calhoun Michael E., Wiederhold Karl-Heinz, Abramowski Dorothee, Phinney Amie L., Probst Alphonse, Sturchler-Pierrat Christine, Staufenbiel Matthias, Sommer Bernd, Jucker Mathias, 10.1038/27351
  46. Games Dora, Adams David, Alessandrini Ree, Barbour Robin, Borthelette Patricia, Blackwell Catherine, Carr Tony, Clemens James, Donaldson Thomas, Gillespie Frances, Guido Terry, Hagopian Stephanie, Johnson-Wood Kelly, Khan Karen, Lee Mike, Leibowitz Paul, Lieberburg Ivan, Little Sheila, Masliah Eliezer, McConlogue Lisa, Montoya-Zavala Martin, Mucke Lennart, Paganini Lisa, Penniman Elizabeth, Power Mike, Schenk Dale, Seubert Peter, Snyder Ben, Soriano Ferdie, Tan Hua, Vitale James, Wadsworth Sam, Wolozin Ben, Zhao Jun, Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein, 10.1038/373523a0
  47. Tu Huiping, Nelson Omar, Bezprozvanny Arseny, Wang Zhengnan, Lee Sheu-Fen, Hao Yi-Heng, Serneels Lutgarde, De Strooper Bart, Yu Gang, Bezprozvanny Ilya, Presenilins Form ER Ca2+ Leak Channels, a Function Disrupted by Familial Alzheimer's Disease-Linked Mutations, 10.1016/j.cell.2006.06.059
  48. Mattson Mark P., Chan Sic L., Dysregulation of Cellular Calcium Homeostasis in Alzheimer's Disease: Bad Genes and Bad Habits, 10.1385/jmn:17:2:205
  49. Mattson Mark P, LaFerla Frank M, Chan Sic L, Leissring Malcolm A, Shepel P.Nickolas, Geiger Jonathan D, Calcium signaling in the ER: its role in neuronal plasticity and neurodegenerative disorders, 10.1016/s0166-2236(00)01548-4
  50. Zoia Chiara P., Tagliabue Elena, Isella Valeria, Begni Barbara, Fumagalli Lorenzo, Brighina Laura, Appollonio Ildebrando, Racchi Marco, Ferrarese Carlo, Fibroblast glutamate transport in aging and in AD: correlations with disease severity, 10.1016/j.neurobiolaging.2004.07.007
  51. Koch Horst, Uyanik Gokhan, Fischer-Barnicol David, Memantine: A Therapeutic Approach in Treating Alzheimers and Vascular Dementia, 10.2174/156800705774322021
  52. Miguel-Hidalgo J.J, Alvarez X.A, Cacabelos R, Quack G, Neuroprotection by memantine against neurodegeneration induced by β-amyloid(1–40), 10.1016/s0006-8993(02)03731-9
  53. Physiol. Rev., 81, 741 (2001)
  54. Snyder S.W., Ladror U.S., Wade W.S., Wang G.T., Barrett L.W., Matayoshi E.D., Huffaker H.J., Krafft G.A., Holzman T.F., Amyloid-beta aggregation: selective inhibition of aggregation in mixtures of amyloid with different chain lengths, 10.1016/s0006-3495(94)80591-0
  55. Hardy J., Higgins G., Alzheimer's disease: the amyloid cascade hypothesis, 10.1126/science.1566067
  56. Schönheit Bärbel, Zarski Rosemarie, Ohm Thomas G, Spatial and temporal relationships between plaques and tangles in Alzheimer-pathology, 10.1016/j.neurobiolaging.2003.09.009