User menu

Transient down-regulation of DNMT1 methyltransferase leads to activation and stable hypomethylation of MAGE-A1 in melanoma cells.

Bibliographic reference Loriot, Axelle ; De Plaen, Etienne ; Boon, Thierry ; De Smet, Charles. Transient down-regulation of DNMT1 methyltransferase leads to activation and stable hypomethylation of MAGE-A1 in melanoma cells.. In: The Journal of biological chemistry, Vol. 281, no. 15, p. 10118-26 (2006)
Permanent URL http://hdl.handle.net/2078.1/10492
  1. Bird A., DNA methylation patterns and epigenetic memory, 10.1101/gad.947102
  2. Pfeifer G. P., Steigerwald S. D., Hansen R. S., Gartler S. M., Riggs A. D., Polymerase chain reaction-aided genomic sequencing of an X chromosome-linked CpG island: methylation patterns suggest clonal inheritance, CpG site autonomy, and an explanation of activity state stability., 10.1073/pnas.87.21.8252
  3. Bestor T. H., The DNA methyltransferases of mammals, 10.1093/hmg/9.16.2395
  4. Okano Masaki, Bell Daphne W, Haber Daniel A, Li En, DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development, 10.1016/s0092-8674(00)81656-6
  5. Li En, Okano Masaki, Xie Shaoping, 10.1038/890
  6. Li En, Bestor Timothy H., Jaenisch Rudolf, Targeted mutation of the DNA methyltransferase gene results in embryonic lethality, 10.1016/0092-8674(92)90611-f
  7. Li En, Beard Caroline, Jaenisch Rudolf, Role for DNA methylation in genomic imprinting, 10.1038/366362a0
  8. Development, 122, 3195 (1996)
  9. EMBO J., 11, 2611 (1992)
  10. Pradhan Sriharsa, Bacolla Albino, Wells Robert D., Roberts Richard J., Recombinant Human DNA (Cytosine-5) Methyltransferase : I. EXPRESSION, PURIFICATION, AND COMPARISON OFDE NOVOAND MAINTENANCE METHYLATION, 10.1074/jbc.274.46.33002
  11. Chen T., Ueda Y., Dodge J. E., Wang Z., Li E., Establishment and Maintenance of Genomic Methylation Patterns in Mouse Embryonic Stem Cells by Dnmt3a and Dnmt3b, 10.1128/mcb.23.16.5594-5605.2003
  12. Riggs Arthur D., Pfeifer Gerd P., X-chromosome inactivation and cell memory, 10.1016/0168-9525(92)90219-t
  13. Hattori N., Preference of DNA Methyltransferases for CpG Islands in Mouse Embryonic Stem Cells, 10.1101/gr.2431504
  14. Adv. Cancer Res., 72, 141 (1998)
  15. Feinberg Andrew P., Vogelstein Bert, Hypomethylation distinguishes genes of some human cancers from their normal counterparts, 10.1038/301089a0
  16. Gama-Sosa Miguel A., Slagel Valerie A., Trewyn Ronald W., Oxenhandler Ronald, Kuo Kenneth C., Gehrke Charles W., Ehrlich Melanie, The 5-methylcytosine content of DNA from human tumors, 10.1093/nar/11.19.6883
  17. Gaudet F., Induction of Tumors in Mice by Genomic Hypomethylation, 10.1126/science.1083558
  18. Feinberg Andrew P., Tycko Benjamin, The history of cancer epigenetics, 10.1038/nrc1279
  19. De Smet C., De Backer O., Faraoni I., Lurquin C., Brasseur F., Boon T., The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation., 10.1073/pnas.93.14.7149
  20. Kaneda Atsushi, Tsukamoto Tetsuya, Takamura-Enya Takeji, Watanabe Naoko, Kaminishi Michio, Sugimura Takashi, Tatematsu Masae, Ushijima Toshikazu, Frequent hypomethylation in multiple promoter CpG islands is associated with global hypomethylation, but not with frequent promoter hypermethylation, 10.1111/j.1349-7006.2004.tb03171.x
  21. van der Bruggen Pierre, Zhang Yi, Chaux Pascal, Stroobant Vincent, Panichelli Christophe, Schultz Erwin S., Chapiro Jacques, Van den Eynde Benoit J., Brasseur Francis, Boon Thierry, Tumor-specific shared antigenic peptides recognized by human T cells, 10.1034/j.1600-065x.2002.18806.x
  22. De Smet C., Loriot A., Boon T., Promoter-Dependent Mechanism Leading to Selective Hypomethylation within the 5' Region of Gene MAGE-A1 in Tumor Cells, 10.1128/mcb.24.11.4781-4790.2004
  23. Ferguson-Smith A. C., Imprinting and the Epigenetic Asymmetry Between Parental Genomes, 10.1126/science.1064020
  24. Beaulieu Normand, Morin Steves, Chute Ian C., Robert Marie-France, Nguyen Hannah, MacLeod A. Robert, An Essential Role for DNA Methyltransferase DNMT3B in Cancer Cell Survival, 10.1074/jbc.m204734200
  25. Robert Marie-France, Morin Steves, Beaulieu Normand, Gauthier France, Chute Ian C., Barsalou Annie, MacLeod A. Robert, DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells, 10.1038/ng1068
  26. Bernard Hans-Ulrich, Krämmer Günter, Röwekamp Walter G., Construction of a fusion gene that confers resistance against hygromycin B to mammalian cells in culture, 10.1016/0014-4827(85)90446-x
  27. De Smet Charles, Courtois Stéphanie J., Faraoni Isabella, Lurquin Christophe, Szikora Jean-Pierre, De Backer Olivier, Boon Thierry, Involvement of two Ets binding sites in the transcriptional activation of the MAGE1 gene, 10.1007/bf00176446
  28. Traversari Catia, van der Bruggen Pierre, Van den Eynde Benoît, Hainaut Philippe, Lemoine Carine, Ohta Nobuyoshi, Old Lloyd, Boon Thierry, Transfection and expression of a gene coding for a human melanoma antigen recognized by autologous cytolytic T lymphocytes, 10.1007/bf00185107
  29. Weynants P., Lethé B., Brasseur F., Marchand M., Boon T., Expression of mage genes by non-small-cell lung carcinomas, 10.1002/ijc.2910560612
  30. Cancer Res., 63, 6110 (2003)
  31. Rhee Ina, Bachman Kurtis E., Park Ben Ho, Jair Kam-Wing, Yen Ray-Whay Chiu, Schuebel Kornel E., Cui Hengmi, Feinberg Andrew P., Lengauer Christoph, Kinzler Kenneth W., Baylin Stephen B., Vogelstein Bert, DNMT1 and DNMT3b cooperate to silence genes in human cancer cells, 10.1038/416552a
  32. Milutinovic Snezana, Zhuang Qianli, Niveleau Alain, Szyf Moshe, Epigenomic Stress Response : KNOCKDOWN OF DNA METHYLTRANSFERASE 1 TRIGGERS AN INTRA-S-PHASE ARREST OF DNA REPLICATION AND INDUCTION OF STRESS RESPONSE GENES, 10.1074/jbc.m213219200
  33. Matsukura S., Establishment of conditional vectors for hairpin siRNA knockdowns, 10.1093/nar/gng077
  34. Yoder Jeffrey A., Walsh Colum P., Bestor Timothy H., Cytosine methylation and the ecology of intragenomic parasites, 10.1016/s0168-9525(97)01181-5
  35. van der Bruggen P, Traversari C, Chomez P, Lurquin C, De Plaen E, Van den Eynde B, Knuth A, Boon T, A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma, 10.1126/science.1840703
  36. Wilson V., Jones P., DNA methylation decreases in aging but not in immortal cells, 10.1126/science.6844925
  37. Flatau E, Gonzales F A, Michalowsky L A, Jones P A, DNA methylation in 5-aza-2'-deoxycytidine-resistant variants of C3H 10T1/2 C18 cells., 10.1128/mcb.4.10.2098
  38. Lorincz M. C., Schubeler D., Goeke S. C., Walters M., Groudine M., Martin D. I. K., Dynamic Analysis of Proviral Induction and De Novo Methylation: Implications for a Histone Deacetylase-Independent, Methylation Density-Dependent Mechanism of Transcriptional Repression, 10.1128/mcb.20.3.842-850.2000
  39. Antequera Francisco, Boyes Joan, Bird Adrian, High levels of De Novo methylation and altered chromatin structure at CpG islands in cell lines, 10.1016/0092-8674(90)90015-7
  40. Jones P. A., Wolkowicz M. J., Rideout W. M., Gonzales F. A., Marziasz C. M., Coetzee G. A., Tapscott S. J., De novo methylation of the MyoD1 CpG island during the establishment of immortal cell lines., 10.1073/pnas.87.16.6117
  41. Cancer Res., 61, 4238 (2001)
  42. Clin. Cancer Res., 9, 4415 (2003)
  43. Fournel Marielle, Sapieha Przemyslaw, Beaulieu Normand, Besterman Jeffrey M., MacLeod A. Robert, Down-regulation of Human DNA-(Cytosine-5) Methyltransferase Induces Cell Cycle Regulators p16ink4Aand p21WAF/Cip1by Distinct Mechanisms, 10.1074/jbc.274.34.24250
  44. Schuebel Kornel E., Rhee Ina, Jair Kam-Wing, Yen Ray-Whay Chiu, Lengauer Christoph, Herman James G., Kinzler Kenneth W., Vogelstein Bert, Baylin Stephen B., 10.1038/35010000
  45. Jaenisch Rudolf, Jackson-Grusby Laurie, Beard Caroline, Possemato Richard, Tudor Matthew, Fambrough Douglas, Csankovszki Györgyi, Dausman Jessica, Lee Peggy, Wilson Christopher, Lander Eric, 10.1038/83730
  46. Ting Angela H, Jair Kam-wing, Suzuki Hiromu, Yen Ray-Whay Chiu, Baylin Stephen B, Schuebel Kornel E, CpG island hypermethylation is maintained in human colorectal cancer cells after RNAi-mediated depletion of DNMT1, 10.1038/ng1365
  47. Cancer Res., 60, 6236 (2000)
  48. Grewal S. I. S., Heterochromatin and Epigenetic Control of Gene Expression, 10.1126/science.1086887
  49. Futscher Bernard W., Oshiro Marc M., Wozniak Ryan J., Holtan Nicholas, Hanigan Christin L., Duan Hong, Domann Frederick E., Role for DNA methylation in the control of cell type–specific maspin expression, 10.1038/ng886
  50. De Smet Charles, Lurquin Christophe, Lethé Bernard, Martelange Valérie, Boon Thierry, DNA Methylation Is the Primary Silencing Mechanism for a Set of Germ Line- and Tumor-Specific Genes with a CpG-Rich Promoter, 10.1128/mcb.19.11.7327
  51. Kafri T, Ariel M, Brandeis M, Shemer R, Urven L, McCarrey J, Cedar H, Razin A, Developmental pattern of gene-specific DNA methylation in the mouse embryo and germ line., 10.1101/gad.6.5.705
  52. Development, 99, 371 (1987)