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Liver transplantation with preservation of the inferior vena cava in case of symptomatic adult polycystic disease.

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Lerut, Jan [UCL] Ciccarelli, Olga [UCL] Rutgers, Matthieu [UCL] Orlando, Giuseppe [UCL] Mathijs, Jules [UCL] Danse, Etienne [UCL] Goffin, Eric [UCL] Gigot, Jean-François [UCL] Goffette, Pierre [UCL]

Adult polycystic liver disease (APLD) is a rare disorder of the liver parenchyma, the treatment of which is still controversial. Conservative surgery may have a significant morbidity and is often ineffective in the long run. Liver replacement may be indicated in case of incapacitating hepatomegaly. Patients (one male, five females) undergoing liver transplantation for symptomatic APLD is presented in this study. The particular nature of this series is the fact that successful transplantation was performed in all cases with preservation of the recipient's inferior vena cava and without use of veno-venous bypass despite massive hepatomegaly and previous extensive liver surgery (in three cases). There was minimal morbidity and no mortality. All patients have excellent quality of life with a median follow-up of 41 months (range: 12-58) as testified by a median Karnofsky score of 90% (range: 80-100%).

Document type Article de périodique (Journal article) – Article de recherche – Case Reports, Journal Article, Research Support, Non-U.S. Gov't
Access type Accès libre
Publication date 2005
Language Anglais
Journal information "Transplant international : official journal of the European Society for Organ Transplantation" - Vol. 18, no. 5, p. 513-8 (2005)
Peer reviewed yes
issn 0934-0874
Publication status Publié
Affiliations UCL - MD/RAIM - Département de radiologie et d'imagerie médicale
UCL - MD/MINT - Département de médecine interne
UCL - (SLuc) Service de radiologie
MESH Subject Adult ; Creatinine - blood ; Female ; Humans ; Liver Transplantation - methods ; Male ; Middle Aged ; Polycystic Kidney, Autosomal Dominant - pathology - physiopathology - surgery ; Quality of Life ; Vena Cava, Inferior - surgery
Links
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Bibliographic reference Lerut, Jan ; Ciccarelli, Olga ; Rutgers, Matthieu ; Orlando, Giuseppe ; Mathijs, Jules ; et. al. Liver transplantation with preservation of the inferior vena cava in case of symptomatic adult polycystic disease.. In: Transplant international : official journal of the European Society for Organ Transplantation, Vol. 18, no. 5, p. 513-8 (2005)
Permanent URL http://hdl.handle.net/2078.1/10155