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Comparison of clinical, magnetic resonance and evoked potentials data in a case of valproic-acid-related hyperammonemic coma.

Bibliographic reference Hantson, Philippe ; Grandin, Cécile ; Duprez, Thierry ; Nassogne, Marie-Cécile ; Guerit, Jean-Michel. Comparison of clinical, magnetic resonance and evoked potentials data in a case of valproic-acid-related hyperammonemic coma.. In: European radiology, Vol. 15, no. 1, p. 59-64 (2005)
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  1. Altunbasak S, Baytok V, Tasouji M et al (1997) Asymptomatic hyperammonemia in children treated with valproic acid. J Child Neurol 12:461?463
  2. Lee WL, Yang CC, Deng JF, Chen YF, Lin HD, Wang PH (1998) A case of severe hyperammonemia and unconsciousness following sodium valproate intoxication. Vet Hum Toxicol 40:346?348
  3. Barrueto F Jr, Hack JB (2001) Hyperammonemia and coma without hepatic dysfunction induced by valproate therapy. Acad Emerg Med 8:999?1001
  4. Feil D, Chuang K, Sultzer DL (2002) Valproate-induced hyperammonemia as a cause of altered mental status. Am J Geriatr Psychiatry 10:476?478
  5. Spiller HA, Krenzelok EP, Klein-Schwartz W et al (2000) Multicenter case series of valproic acid ingestion: serum concentrations and toxicity. J Toxicol Clin Toxicol 38:755?760
  6. Duarte J, Macias S, Coria F, Fernandez E, Claveria LE (1993) Valproate-induced coma: case report and review of the literature. Ann Pharmacother 27:582?583
  7. Gu�rit JM, de Tourtchaninoff M, Soveges L, Mahieu P (1993) The prognostic value of three-modality evoked potentials (TMEPs) in anoxic and traumatic comas. Neurophysiol Clin 23:209?226
  8. Sztajnkrycer MD (2002) Valproic acid toxicity: overview and management. J Toxicol Clin Toxicol 40:789?801
  9. Ratnaike RN, Schapel GJ, Purdie G, Rischbieth RH, Hoffmann S (1986) Hyperammonaemia and hepatotoxicity during chronic valproate therapy: enhancement by combination with other antiepileptic drugs. Br J Clin Pharmacol 22:100?103
  10. Hamer HM, Knake S, Schomburg U, Rosenow F (2000) Valproate-induced hyperammonemic encephalopathy in the presence of topiramate. Neurology 54:230?232
  11. Dupuis RE, Lichtman SN, Pollack GM (1990) Acute valproic acid overdose: clinical course and pharmacokinetic disposition of valproic acid and metabolites. Drug Saf 5:65?71
  12. Khoo SH, Leyland MJ (1992) Cerebral edema following acute sodium valproate overdose. J Toxicol Clin Toxicol 30:209?214
  13. Triggs WJ, Gilmore RL, Millington DS, Cibula J, Bunch TS, Harman E (1997) Valproate-associated carnitine deficiency and malignant cerebral edema in the absence of hepatic failure. Int J Clin Pharmacol Ther 35:353?356
  14. Baganz MD, Dross PE (1994) Valproic acid-induced hyperammonemic encephalopathy: MR appearance. Am J Neuroradiol 15:1779?1781
  15. Ziyeh S, Thiel T, Spreer J, Klisch J, Schumacher M (2002) Valproate-induced encephalopathy: assessment with MR imaging and 1H MR spectroscopy. Epilepsia 43:1101?1105
  16. Schaefer Pamela W., Grant P. Ellen, Gonzalez R. Gilberto, Diffusion-weighted MR Imaging of the Brain, 10.1148/radiology.217.2.r00nv24331
  17. Wieshmann UC, Symms MR, Shorvon SD (1997) Diffusion changes in status epilepticus. Lancet 350:493?494
  18. Collins RM Jr, Zielke HR, Woody RC (1994) Valproate increases glutaminase and decreases glutamine synthetase activities in primary cultures of rat brain astrocytes. J Neurochem 62:1137?1143
  19. Blindauer K. A., Harrington G., Morris G. L., Ho K.-C., Fulminant progression of demyelinating disease after valproate-induced encephalopathy, 10.1212/wnl.51.1.292
  20. Rovira A, Cordoba J, Raguer N, Alonso J (2002) Magnetic resonance imaging measurement of brain edema in patients with liver disease: resolution after transplantation. Curr Opin Neurol 15:731?737
  21. Dolman CL, Clasen RA, Dorovini-Zis K (1988) Severe cerebral damage in ornithine transcarbamylase deficiency. Clin Neuropathol 7:10?15
  22. Mirowitz SA, Saitor K, Prensky AJ, Gado M, Hodges FJ (1991) Neurodegenerative diseases of childhood: MR and CT evaluation. J Comput Assist Tomogr 15:210
  23. Mamourian AC, du Plessis A (1991) Urea cycle defect: a case with MR and CT findings resembling infarct. Pediatr Radiol 21:594?595
  24. Takanashi J, Barkovich J, Cheng S, Kostiner D, Baker J, Packman S (2003) Brain MR imaging in acute hyperammonemic encephalopathy arising from late-onset ornithine transcarbamylase deficiency. Am J Neuroradiol 24:390?393
  25. Chen YF, Huang YC, Liu HM, Hwu WL (2001) MRI in a case of adult-onset citrullinemia. Neuroradiology 43:845?847