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Affichage: 1 - 25 sur 78 résultats.

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    • Article de périodique
    In situ modulation of oxidative stress: a novel and efficient strategy to kill cancer cells
    Verrax, Julien[UCL] Pedrosa, R Curi[UCL] Beck, Raphaël[UCL] Dejeans, Nicolas[UCL] Taper, Henryk[UCL] Buc Calderon, Pedro[UCL] (2009) Current Medicinal Chemistry — Vol. 16, no. 15, p. 1821-1830 (2009)
    • Article de périodique
    Comparison of methods to measure oxygen consumption in tumor cells in vitro
    Diepart, Caroline[UCL] Verrax, Julien[UCL] Buc Calderon, Pedro[UCL] Feron, Olivier[UCL] Jordan, Bénédicte[UCL] Gallez, Bernard[UCL] (2009) Analytical Biochemistry — Vol. 396, no. 2, p. 250-256 (2010)
    • Article de périodique
    Synthesis and antitumor evaluation of 8-phenylaminopyrimido[4,5-c]isoquinolinequinones
    Vasquez, David Rodriguez, Jaime A. Theoduloz, Cristina Verrax, Julien[UCL] Buc Calderon, Pedro[UCL] Valderrama, Jaime A. (2009) Bioorganic & Medicinal Chemistry Letters : the tetrahedron journal for research at the interface of chemistry and biology — Vol. 19, no. 17, p. 5060-5062 (2009)
    • Article de périodique
    Cancer : lorsque recycler devient une faiblesse.
    Sonveaux, Pierre[UCL] Végran, Frédérique[UCL] Verrax, Julien[UCL] De Saedeleer, Christophe[UCL] Diepart, Caroline[UCL] Jordan, Bénédicte[UCL] Gallez, Bernard[UCL] Feron, Olivier[UCL] (2009) Médecine, sciences - MS — Vol. 25, no. 4, p. 327-329 (2009)
    • Article de périodique
    Menadione reduction by pharmacological doses of ascorbate induces an oxidative stress that kills breast cancer cells.
    Beck, Raphaël[UCL] Verrax, Julien[UCL] Dejeans, Nicolas[UCL] Taper, Henryk[UCL] Buc Calderon, Pedro[UCL] (2009) International Journal of Toxicology — Vol. 28, no. 1, p. 33-42 (2009)
    • Article de périodique
    Ascorbate/menadione-induced oxidative stress kills cancer cells that express normal or mutated forms of the oncogenic protein Bcr-Abl. An in vitro and in vivo mechanistic study
    Beck, Raphaël[UCL] Eeckhoudt, Stéphane[UCL] Knoops, Laurent[UCL] Pedrosa, Rozangela Curi Dejeans, Nicolas[UCL] Glorieux, Christophe[UCL] Levêque, Philippe[UCL] Gallez, Bernard[UCL] Taper, Henryk[UCL] Buc Calderon, Pedro[UCL] Verrax, Julien[UCL] (2011) Investigational New Drugs : the journal of new anti-cancer agents — Vol. 29, no. 5, p. 891-900 (2011)
    • Article de périodique
    The controversial place of vitamin C in cancer treatment
    Verrax, Julien[UCL] Buc Calderon, Pedro[UCL] (2008) Biochemical Pharmacology — Vol. 76, no. 12, p. 1644-1652 (2008)
    • Article de périodique
    Hsp90 cleavage by an oxidative stress leads to its client proteins degradation and cancer cell death.
    Beck, Raphaël[UCL] Verrax, Julien[UCL] Gonze, Thomas[UCL] Zappone, Marianne[UCL] Pedrosa, Rozangela Curi Taper, Henryk[UCL] Feron, Olivier[UCL] Buc Calderon, Pedro[UCL] (2009) Biochemical Pharmacology — Vol. 77, no. 3, p. 375-383 (2009)
    • Article de périodique
    Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
    Sonveaux, Pierre[UCL] Végran, Frédérique[UCL] Schroeder, Thies Wergin, Melanie C. Verrax, Julien[UCL] Rabbani, Zahid N. De Saedeleer, Christophe[UCL] Kennedy, Kelly M. Diepart, Caroline[UCL] Jordan, Bénédicte[UCL] Kelley, Michael J. Gallez, Bernard[UCL] Wahl, Miriam L. Feron, Olivier[UCL] Dewhirst, Mark W. (2008) Journal of Clinical Investigation — Vol. 118, no. 12, p. 3930-3942 (2008)
    • Article de périodique
    AICAR induces Nrf2 activation by an AMPK-independent mechanism in hepatocarcinoma cells
    Sid, Brice[UCL] Glorieux, Christophe[UCL] Valenzuela Valderrama, Manuel Alejandro[UCL] Rommelaere, Guillaume Najimi, Mustapha[UCL] Dejeans, Nicolas[UCL] Renard, Patricia Verrax, Julien[UCL] Buc Calderon, Pedro[UCL] (2014) Biochemical Pharmacology — Vol. 91, no. 2, p. 168-180 (2014)
    • Article de périodique
    Le stress oxydatif, une arme à double tranchant pour les cellules cancéreuses?
    Verrax, Julien[UCL] (2011) Onco — Vol. 5, no. 6, p. 231-234 (Octobre/Novembre 2011)
    • Communication
    Disruption of Hsp90 function by reactive oxygen species: a new mechanism explaining the antitumoral effects of quinone compounds
    Verrax, Julien[UCL] (2011) BIT's 9th Annual Congress of International Drug Discovery Science and Technology — Shenzhen, China
    • Communication
    Oxidant-mediated cancer cell death: targeting glycolysis to kill
    Verrax, Julien[UCL] Taper, Henryk[UCL] Buc Calderon, Pedro[UCL] (2006) 6ème Réunion du Groupe de Contact FNRS « Phénomènes oxydatifs en antioxydants » — Brussels, Belgium
    • Article de périodique
    Gut microbiota-derived propionate reduces cancer cell proliferation in the liver
    Bindels, Laure B.[UCL] Porporato, Paolo[UCL] Dewulf, Evelyne[UCL] Verrax, Julien[UCL] Neyrinck, Audrey M.[UCL] Martin, J C Scott, K P Buc Calderon, Pedro[UCL] Feron, Olivier[UCL] Muccioli, Giulio[UCL] Sonveaux, Pierre[UCL] Cani, Patrice D.[UCL] Delzenne, Nathalie M.[UCL] (2012) The British journal of cancer — Vol. 107, no. 8, p. 1337-1344 (2012)
    • Article de périodique
    Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells
    De Saedeleer, Christophe[UCL] Copetti, Tamara[UCL] Porporato, Paolo[UCL] Verrax, Julien[UCL] Feron, Olivier[UCL] Sonveaux, Pierre[UCL] (2012) PLoS One — Vol. 7, no. 10, p. e46571 (2012)
    • Article de périodique
    Oxidative stress by ascorbate/menadione association kills K562 human chronic myelogenous leukaemia cells and inhibits its tumour growth in nude mice.
    Verrax, Julien[UCL] Stockis, Julie[UCL] Tison, Aurélie Taper, Henryk[UCL] Buc Calderon, Pedro[UCL] (2006) Biochemical pharmacology — Vol. 72, no. 6, p. 671-80 (2006)
    • Article de périodique
    Botulinum toxin potentiates cancer radiotherapy and chemotherapy.
    Ansiaux, Réginald[UCL] Baudelet, Christine[UCL] Cron, Greg O.[UCL] Segers, Jérôme[UCL] Dessy, Chantal[UCL] Martinive, Philippe[UCL] De Wever, Julie[UCL] Verrax, Julien[UCL] Wauthier, Valérie[UCL] Beghein, Nelson[UCL] Grégoire, Vincent[UCL] Buc Calderon, Pedro[UCL] Feron, Olivier[UCL] Gallez, Bernard[UCL] (2006) Clinical cancer research : an official journal of the American Association for Cancer Research — Vol. 12, no. 4, p. 1276-83 (2006)
    • Article de périodique
    Role of glycolysis inhibition and poly(ADP-ribose) polymerase activation in necrotic-like cell death caused by ascorbate/menadione-induced oxidative stress in K562 human chronic myelogenous leukemic cells.
    Verrax, Julien[UCL] Vanbever, Stéphanie Stockis, Julie[UCL] Taper, Henryk[UCL] Buc Calderon, Pedro[UCL] (2007) International Journal of Cancer — Vol. 120, no. 6, p. 1192-7 (2007)
    • Communication
    Enhancement of quinone redox cycling by ascorbate leads to cancer cell death through a caspase-3 independent pathway. An in vitro comparative study.
    Verrax, Julien[UCL] Delvaux, Marianne[UCL] Beghein, Nelson[UCL] Taper, Henryk[UCL] Gallez, Bernard[UCL] Buc Calderon, Pedro[UCL] (2004) Joint meeting of the Belgian Society of Biochemistry and Molecular Biology and the FNRS Contact Group on Oxidative Stress and Antioxidants — Liège, Belgium
    • Article de périodique
    New insights about the potential application of the association of vitamins C (sodium ascorbate) and K3 (menadione) as auxiliary therapy in cancer treatment
    Verrax, Julien[UCL] Bollen, S[UCL] Delvaux, M.[UCL] Taper, H.[UCL] Buc Calderon, Pedro[UCL] (2005) Medicinal Chemistry Reviews - Online — Vol. 2, no. 4, p. 277-282 (2005)
    • Article de périodique
    Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis
    Sonveaux, Pierre[UCL] Copetti, Tamara[UCL] De Saedeleer, Christophe[UCL] Végran, Frédérique[UCL] Verrax, Julien[UCL] Kennedy, Kelly M Moon, Eui Jung Dhup, Suveera[UCL] Danhier, Pierre[UCL] Frérart, Françoise[UCL] Gallez, Bernard[UCL] Ribeiro, Anthony Michiels, Carine Dewhirst, Mark W Feron, Olivier[UCL] (2012) PLoS One — Vol. 7, no.3, p. e33418 [1-13] (2012)
    • Article de périodique
    Antiproliferative effects of phenylaminonaphthoquinones are increased by ascorbate and associated with the appearance of a senescent phenotype in human bladder cancer cells
    Bettega Felipe, Karina Benites, Julio Glorieux, Christophe[UCL] Sid, Brice[UCL] Valenzuela Valderrama, Manuel Alejandro[UCL] Kviecinski, Maicon Roberto Pedrosa, Rozangela Curi Valderrama, Jaime Adolfo Levêque, Philippe[UCL] Gallez, Bernard[UCL] Verrax, Julien[UCL] Buc Calderon, Pedro[UCL] (2013) Biochemical and Biophysical Research Communications — Vol. 433, no. 4, p. 573-578 (2013)
    • Communication
    Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced angiogenesis
    Copetti, Tamara[UCL] De Saedeleer, Christophe[UCL] Vegran, Frédérique[UCL] Verrax, Julien[UCL] Kennedy, Kelly M Moon, Eui J Dhup, Suveera[UCL] Danhier, Pierre[UCL] Frérart, Françoise[UCL] Gallez, Bernard[UCL] Ribeiro, Anthony Michiels, Carine[FUNDP] Dewhirst, Mark W Feron, Olivier[UCL] Sonveaux, Pierre[UCL] (2014) 4th annual meeting of the ISPDC — Munich, Germany
    • Article de périodique
    Use of a cocktail of spin traps for fingerprinting large range of free radicals in biological systems.
    Marchand, Valérie[UCL] Charlier, Nicolas[UCL] Verrax, Julien[UCL] Buc Calderon, Pedro[UCL] Levêque, Philippe[UCL] Gallez, Bernard[UCL] (2017) PLoS One — Vol. 12, p. e0172998 [1-15] (2017)
    • Thèse
    Study of the molecular mechanisms involved in cancer cell death following the exposure to the combination of ascorbate (vitamin C) and menadione (vitamin K3)
    Verrax, Julien[UCL] (2006)

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