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Affichage: 3 résultats.
    • Article de périodique
    Investigation of mechanism-based thrombin inhibitors: Implications of a highly conserved water molecule for the binding of coumarins within the S pocket.
    Frédérick, Raphaël[UCL] Charlier, Caroline[FUNDP] Robert, S.[FUNDP] Wouters, Johan[FUNDP] Masereel, Bernard[FUNDP] Pochet, Lionel[FUNDP] (2006) Bioorganic & Medicinal Chemistry Letters : the tetrahedron journal for research at the interface of chemistry and biology — Vol. 16, no. 7, p. 2017-2021 (2006)
    • Article de périodique
    3,6-disubstituted coumarins as mechanism-based inhibitors of thrombin and factor Xa
    Frédérick, Raphaël[UCL] Robert, S.[FUNDP] Charlier, Caroline[FUNDP] de Ruyck, Jérôme Wouters, Johan[FUNDP] Pirotte, Bernard Masereel, Bernard[FUNDP] Pochet, Lionel[FUNDP] (2005) Journal of Medicinal Chemistry — Vol. 48, no. 24, p. 7592-7603 (2005)
    • Article de périodique
    Mechanism-based thrombin inhibitors: design, synthesis, and molecular docking of a new selective 2-oxo-2H-1-benzopyran derivative.
    Frédérick, Raphaël[UCL] Robert, S.[FUNDP] Charlier, Caroline[FUNDP] Wouters, Johan[FUNDP] Masereel, Bernard[FUNDP] Pochet, Lionel[FUNDP] (2007) Journal of medicinal chemistry — Vol. 50, no. 15, p. 3645-3650 (2007)