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Affichage: 25 résultats.
    • Article de périodique
    An optimized dRVVT-based assay to estimate the intensity of anticoagulation in patients treated with direct oral anticoagulants.
    Sennesael, Anne-Laure[UCL] Exner, Thomas Chatelain, Bernard[UCL] Lessire, Sarah[UCL] Larock, Anne-Sophie[UCL] Vancraeynest, Christelle[UCL] Pochet, Lionel Dogné, Jean-Michel[UCL] Spinewine, Anne[UCL] Mullier, François[UCL] Douxfils, Jonathan[UCL] (2017) Thrombosis Research : vascular obstruction, hemorrhage and hemostasis — Vol. 157, p. 29-37 (2017)
    • Article de périodique
    Synthesis, evaluation and structure-activity relationship of new 3-carboxamide coumarins as FXIIa inhibitors
    Bouckaert, Charlotte[FUNDP] Serra, Silvia[FUNDP] Rondelet, Grégoire[FUNDP] Dolušić, Eduard[FUNDP] Wouters, Johan[FUNDP] Dogné, Jean-Michel[FUNDP] Frédérick, Raphaël[UCL] Pochet, Lionel[FUNDP] (2016) European Journal of Medicinal Chemistry — Vol. 110, p. 181-194 (2016)
    • Article de périodique
    3D-QSAR, design, synthesis and characterization of trisubstituted harmine derivatives with in vitro antiproliferative properties
    Meinguet, Céline Bruyère, Céline Frédérick, Raphaël[UCL] Mathieu, Véronique Vancraeynest, Christelle Pochet, Lionel Laloy, Julie Mortier, Jérémie Wolber, Gerhard Kiss, Robert Masereel, Bernard Wouters, Johan (2015) European Journal of Medicinal Chemistry — Vol. 94, no. 1, p. 45-55 (2015)
    • Article de périodique
    Novel trisubstituted harmine derivatives with original in vitro anticancer activity
    Frédérick, Raphaël[UCL] Bruyére, Céline Vancraeynest, Christelle[FUNDP] Reniers, Jérémy[FUNDP] Meinguet, Céline[FUNDP] Pochet, Lionel[FUNDP] Backlund, Anders Masereel, Bernard[FUNDP] Kiss, Robert Wouters, Johan[FUNDP] (2012) Journal of Medicinal Chemistry — Vol. 55, no. 14, p. 6489-6501 (2012)
    • Article de périodique
    Thiosemicarbazide, a fragment with promising indolamine-2,3-dioxygenase (IDO) inhibition properties
    Serra, Silvia[FUNDP] Moineaux, Laurence[FUNDP] Vancraeynest, Christelle[FUNDP] Masereel, Bernard[FUNDP] Wouters, Johan[FUNDP] Pochet, Lionel[FUNDP] Frédérick, Raphaël[UCL] (2014) European Journal of Medicinal Chemistry — Vol. 82, p. 96-105 (2014)
    • Article de périodique
    Pyrazolo[4,3-c]isoquinolines as potential inhibitors of NF-κB activation
    Mortier, Jérémie[FUNDP] Frédérick, Raphaël[UCL] Ganeff, Corinne Remouchamps, Caroline Talaga, Patrice Pochet, Lionel[FUNDP] Wouters, Johan[FUNDP] Piette, Jacques Dejardin, Emmanuel Masereel, Bernard[FUNDP] (2010) Biochemical Pharmacology — Vol. 79, no. 10, p. 1462-1472 (2010)
    • Article de périodique
    Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators
    Dolusic, Eduard[FUNDP] Larrieu, Pierre[UCL] Moineaux, Laurence[FUNDP] Stroobant, Vincent[UCL] Pilotte, Luc[UCL] Colau, Didier[UCL] Pochet, Lionel[FUNDP] Van den Eynde, Benoît[UCL] Masereel, Bernard[FUNDP] Wouters, Johan[FUNDP] Frédérick, Raphaël[FUNDP] (2011) Journal of Medicinal Chemistry — Vol. 54, no. 15, p. 5320-5334 (11/08/2011)
    • Article de périodique
    Modulators of the coagulation cascade: focus and recent advances in inhibitors of tissue factor, factor VIIa and their complex
    Frédérick, Raphaël[UCL] Pochet, Lionel[FUNDP] Charlier, Caroline[FUNDP] Masereel, Bernard[FUNDP] (2005) Current medicinal chemistry — Vol. 12, no. 4, p. 397-417 (2005)
    • Article de périodique
    Coumarin and isocoumarin as serine protease inhibitors
    Pochet, Lionel[FUNDP] Frédérick, Raphaël[UCL] Masereel, Bernard[FUNDP] (2004) Current pharmaceutical design — Vol. 10, no. 30, p. 3781-3796 (2004)
    • Article de périodique
    Investigation of the inhibition mechanism of coumarins on chymotrypsin by mass spectrometry
    Pochet, Lionel[FUNDP] Dieu, Marc[FUNDP] Frédérick, Raphaël[UCL] Murray, Anne-Marie[FUNDP] Kempen, Isabelle Pirotte, Bernad Masereel, Bernard[FUNDP] (2003) Tetrahedron — Vol. 59, no. 25, p. 4557-4561 (2003)
    • Article de périodique
    Effect of ABCB1 genetic polymorphisms on the transport of rivaroxaban in HEK293 recombinant cell lines
    Sennesael, Anne-Laure[UCL] Panin, Nadtha[UCL] Vancraeynest, Christelle Pochet, Lionel Spinewine, Anne[UCL] Haufroid, Vincent[UCL] Elens, Laure[UCL] (2018) Scientific Reports — Vol. 8, no. 1, p. 10514 [1-6] (2018)
    • Article de périodique
    29ièmes Journées Franco-Belges de Pharmacochimie: Meeting Report
    The Members of the Organizing Committee Frédérick, Raphaël[UCL] Pochet, Lionel[FUNDP] De Tullio, Pascal Dufrasne, François E.[UCL] (2015) Pharmaceuticals — Vol. 8, no.4, p. 758-777 (2015)
    • Article de périodique
    31ièmes Journées Franco-Belges de Pharmacochimie: Meeting Report.
    Frédérick, Raphaël[UCL] Pochet, Lionel De Tullio, Pascal Dufrasne, François (2017) Pharmaceuticals — Vol. 10, p. 94 [1-12] (2017)
    • Article de périodique
    Betrixaban: Impact on Routine and Specific Coagulation Assays-A Practical Laboratory Guide.
    Siriez, Romain Evrard, Jonathan Dogné, Jean-Michel Pochet, Lionel Gheldof, Damien Chatelain, Bernard[UCL] Mullier, François[UCL] Douxfils, Jonathan (2018) Thrombosis and haemostasis — Vol. 118, no. 7, p. 1203-1214 (2018)
    • Article de périodique
    Development and validation of a liquid chromatography/tandem mass spectrometry method for the simultaneous quantification of serotonin and thromboxane B2 from activated platelets.
    Mine, Valentine Evrard, Jonathan Vancraeynest, Christelle Dogné, Jean-Michel Mullier, François[UCL] Pochet, Lionel (2018) International journal of laboratory hematology — Vol. 40, no. 6, p. 663-371 (2018)
    • Article de périodique
    Pharmacomodulations of the benzoyl-thiosemicarbazide scaffold reveal antimicrobial agents targeting D-alanyl-D-alanine ligase in bacterio
    Ameryckx, Alice[UCL] Pochet, Lionel Wang, Gang[UCL] Yildiz, Esra[UCL] Es Saadi, Bouazza[UCL] Wouters, Johan Van Bambeke, Françoise[UCL] Frédérick, Raphaël[UCL] (2020) European Journal of Medicinal Chemistry — Vol. 200, no.1, p. 112444 (2020)
    • Article de périodique
    Investigation of mechanism-based thrombin inhibitors: Implications of a highly conserved water molecule for the binding of coumarins within the S pocket.
    Frédérick, Raphaël[UCL] Charlier, Caroline[FUNDP] Robert, S.[FUNDP] Wouters, Johan[FUNDP] Masereel, Bernard[FUNDP] Pochet, Lionel[FUNDP] (2006) Bioorganic & Medicinal Chemistry Letters : the tetrahedron journal for research at the interface of chemistry and biology — Vol. 16, no. 7, p. 2017-2021 (2006)
    • Article de périodique
    Mechanism-based thrombin inhibitors: design, synthesis, and molecular docking of a new selective 2-oxo-2H-1-benzopyran derivative.
    Frédérick, Raphaël[UCL] Robert, S.[FUNDP] Charlier, Caroline[FUNDP] Wouters, Johan[FUNDP] Masereel, Bernard[FUNDP] Pochet, Lionel[FUNDP] (2007) Journal of medicinal chemistry — Vol. 50, no. 15, p. 3645-3650 (2007)
    • Article de périodique
    3,6-disubstituted coumarins as mechanism-based inhibitors of thrombin and factor Xa
    Frédérick, Raphaël[UCL] Robert, S.[FUNDP] Charlier, Caroline[FUNDP] de Ruyck, Jérôme Wouters, Johan[FUNDP] Pirotte, Bernard Masereel, Bernard[FUNDP] Pochet, Lionel[FUNDP] (2005) Journal of Medicinal Chemistry — Vol. 48, no. 24, p. 7592-7603 (2005)
    • Article de périodique
    Development of new methodologies for the chromogenic estimation of betrixaban concentrations in plasma.
    Siriez, Romain Evrard, Jonathan Dogné, Jean-Michel Pochet, Lionel Bouvy, Céline Lessire, Sarah[UCL] Mullier, François[UCL] Douxfils, Jonathan (2019) International journal of laboratory hematology — Vol. 41, no. 2, p. 250-261 (2019)
    • Article de périodique
    Assessment of low plasma concentrations of apixaban in the periprocedural setting.
    Lessire, Sarah[UCL] Dincq, Anne-Sophie[UCL] Siriez, Romain Pochet, Lionel Sennesael, Anne-Laure[UCL] Vornicu, Ovidiu Ionut[UCL] Hardy, Michaël[UCL] Deceuninck, Olivier[UCL] Douxfils, Jonathan Mullier, François[UCL] (2020) International journal of laboratory hematology — Vol. 42, no. 4, p. 394-402 (2020)
    • Article de périodique
    1-(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting d-alanine-d-alanine ligase in bacterio
    Ameryckx, Alice[UCL] Thabault, Léopold[UCL] Pochet, Lionel Leimanis, Serge Poupaert, Jacques[UCL] Wouters, Johan Joris, Bernard Van Bambeke, Françoise[UCL] Frédérick, Raphaël[UCL] (2018) European Journal of Medicinal Chemistry — Vol. 159, p. 324-338 (2018)
    • Article de périodique
    Mass spectrometry in the therapeutic drug monitoring of direct oral anticoagulants. Useful or useless?
    Douxfils, Jonathan[FUNDP] Pochet, Lionel[FUNDP] Lessire, Sarah[UCL] Vancraeynest, Christelle[FUNDP] Dogné, Jean-Michel[FUNDP] Mullier, François[UCL] (2016) Trends in Analytical Chemistry — Vol. 84, no. nov, p. 41-50 (2016)
    • Article de périodique
    Convenient one-pot formation of highly functionalized 5-bromo-2-aminothiazoles, potential endocannabinoid hydrolase MAGL inhibitors
    Prevost, Julien R.C.[UCL] Kozlova, Arina[UCL] Es Saadi, Bouazza[UCL] Yildiz, Esra[UCL] Modaffari, Sara Lambert, Didier M.[UCL] Pochet, Lionel Wouters, Johan Dolušić, Eduard Frédérick, Raphaël[UCL] (2018) Tetrahedron Letters — Vol. 59, no.49, p. 4315-4319 (2018)
    • Article de périodique
    Estimation of Rivaroxaban Plasma Concentrations in the Perioperative Setting in Patients With or Without Heparin Bridging.
    Lessire, Sarah[UCL] Douxfils, Jonathan Pochet, Lionel Dincq, Anne-Sophie[UCL] Larock, Anne-Sophie[UCL] Gourdin, Maximilien[UCL] Dogné, Jean-Michel Chatelain, Bernard[UCL] Mullier, François[UCL] (2018) Clinical and Applied Thrombosis / Hemostasis — Vol. 24, no. 1, p. 129-138 (2018)