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Affichage: 25 résultats.
    • Article de périodique
    Strengths and limitations of industry vs. academic randomized controlled trials.
    Laterre, Pierre-François[UCL] François, Bruno (2015) Clinical Microbiology and Infection — Vol. 21, no. 10, p. 906-909 (2015)
    • Article de périodique
    Association between timing of intubation and outcome in critically ill patients: A secondary analysis of the ICON audit.
    Bauer, Philippe R Gajic, Ognjen Nanchal, Rahul Kashyap, Rahul Martin-Loeches, Ignacio Sakr, Yasser Jakob, Stephan M François, Bruno Wittebole, Xavier[UCL] Wunderink, Richard G Vincent, Jean-Louis ICON Investigators Dive, Alain-Michel[UCL] (2017) Journal of Critical Care — Vol. 42, p. 1-5 (2017)
    • Article de périodique
    Assessment of the worldwide burden of critical illness: the intensive care over nations (ICON) audit.
    Vincent, Jean-Louis Marshall, John C Namendys-Silva, Silvio A François, Bruno Martin-Loeches, Ignacio Lipman, Jeffrey Reinhart, Konrad Antonelli, Massimo Pickkers, Peter Njimi, Hassane Jimenez, Edgar Sakr, Yasser ICON investigators Wittebole, Xavier[UCL] Dive, Alain-Michel[UCL] (2014) The Lancet Respiratory Medicine — Vol. 2, no.5, p. 380-386 (2014)
    • Article de périodique
    Perspective on optimizing clinical trials in critical care: how to puzzle out recurrent failures.
    François, Bruno Clavel, Marc Vignon, Philippe Laterre, Pierre-François[UCL] (2016) Journal of intensive care — Vol. 4, no. 1, p. 67 [1-11] (2016)
    • Article de périodique
    CAL02, a novel antitoxin liposomal agent, in severe pneumococcal pneumonia: a first-in-human, double-blind, placebo-controlled, randomised trial.
    Laterre, Pierre-François[UCL] Colin, Gwenhael Dequin, Pierre-François Dugernier, Thierry Boulain, Thierry Azeredo da Silveira, Samareh Lajaunias, Frédéric Perez, Antonio François, Bruno (2019) The Lancet. Infectious diseases — Vol. 19, no.6, p. 620-630 (2019)
    • Article de périodique
    The SAATELLITE and EVADE Clinical Studies Within the COMBACTE Consortium: A Public-Private Collaborative Effort in Designing and Performing Clinical Trials for Novel Antibacterial Drugs to Prevent Nosocomial Pneumonia.
    François, Bruno Chastre, Jean Eggiman, Philippe Laterre, Pierre-François[UCL] Torres, Antoni Sanchez, Miguel Esser, Mark T Bishop, Brian Bonten, Marc Goosens, Herman Jafri, Hasan S (2016) Clinical Infectious Diseases — Vol. 63, no. suppl 2, p. S46-S51 (2016)
    • Article de périodique
    Effect of Selepressin vs Placebo on Ventilator- and Vasopressor-Free Days in Patients With Septic Shock: The SEPSIS-ACT Randomized Clinical Trial.
    Laterre, Pierre-François[UCL] Berry, Scott M Blemings, Allan Carlsen, Jan E François, Bruno Graves, Todd Jacobsen, Karsten Lewis, Roger J Opal, Steven M Perner, Anders Pickkers, Peter Russell, James A Windeløv, Nis A Yealy, Donald M Asfar, Pierre Bestle, Morten H Muller, Grégoire Bruel, Cédric Brulé, Noëlle Decruyenaere, Johan Dive, Alain-Michel[UCL] Dugernier, Thierry Krell, Kenneth Lefrant, Jean-Yves Megarbane, Bruno Mercier, Emmanuelle Mira, Jean-Paul Quenot, Jean-Pierre Rasmussen, Bodil Steen Thorsen-Meyer, Hans-Christian Vander Laenen, Margot Vang, Marianne Lauridsen Vignon, Philippe Vinatier, Isabelle Wichmann, Sine Wittebole, Xavier[UCL] Kjølbye, Anne Louise Angus, Derek C SEPSIS-ACT Investigators (2019) JAMA — Vol. 322, no. 15, p. 1476-1485 (2019)
    • Article de périodique
    Pseudomonas aeruginosa serotypes in nosocomial pneumonia: prevalence and clinical outcomes
    Lu, Qin Eggimann, Philippe Luyt, Charles-Edouard Wolff, Michel Tamm, Michael François, Bruno Mercier, Emmanuelle Garbino, Jorge Laterre, Pierre-François[UCL] Koch, Holger Gafner, Verena Rudolf, Michael P Mus, Erkan Perez, Antonio Lazar, Hedvika Chastre, Jean Rouby, Jean-Jacques (2014) Critical Care — Vol. 18, no.1, p. R17 [1-9] (2014)
    • Article de périodique
    A worldwide multicentre evaluation of the influence of deterioration or improvement of acute kidney injury on clinical outcome in critically ill patients with and without sepsis at ICU admission: results from The Intensive Care Over Nations audit.
    Peters, Esther Antonelli, Massimo Wittebole, Xavier[UCL] Nanchal, Rahul François, Bruno Sakr, Yasser Vincent, Jean-Louis Pickkers, Peter (2018) Critical Care — Vol. 22, no.1, p. 188 (2018)
    • Article de périodique
    Proenkephalin A 119-159 (Penkid) Is an Early Biomarker of Septic Acute Kidney Injury: The Kidney in Sepsis and Septic Shock (Kid-SSS) Study.
    Hollinger, Alexa Wittebole, Xavier[UCL] François, Bruno Pickkers, Peter Antonelli, Massimo Gayat, Etienne Chousterman, Benjamin Glen Lascarrou, Jean-Baptiste Dugernier, Thierry Di Somma, Salvatore Struck, Joachim Bergmann, Andreas Beishuizen, Albertus Constatin, Jean-Michel Damoisel, Charles Deye, Nicolas Gaudry, Stéphane Huberlant, Vincent Marx, Gernot Mercier, Emanuelle Oueslati, Haikel Hartmann, Oliver Sonneville, Romain Laterre, Pierre-François[UCL] Mebazaa, Alexandre Legrand, Matthieu (2018) Kidney International Reports — Vol. 3, no.6, p. 1424-1433 (2018)
    • Article de périodique
    Circulating adrenomedullin estimates survival and reversibility of organ failure in sepsis: the prospective observational multinational Adrenomedullin and Outcome in Sepsis and Septic Shock-1 (AdrenOSS-1) study.
    Mebazaa, Alexandre Geven, Christopher Hollinger, Alexa Wittebole, Xavier[UCL] Chousterman, Benjamin Glen Blet, Alice Gayat, Etienne Hartmann, Oliver Scigalla, Paul Struck, Joachim Bergmann, Andreas Antonelli, Massimo Beishuizen, Albertus Constantin, Jean-Michel Damoisel, Charles Deye, Nicolas Di Somma, Salvatore Dugernier, Thierry François, Bruno Gaudry, Stephane Huberlant, Vincent Lascarrou, Jean-Baptiste Marx, Gernot Mercier, Emmanuelle Oueslati, Haikel Pickkers, Peter Sonneville, Romain Legrand, Matthieu Laterre, Pierre-François[UCL] AdrenOSS-1 study investigators (2018) Critical Care — Vol. 22, no.1, p. 354 (2018)
    • Article de périodique
    Nangibotide in patients with septic shock: a Phase 2a randomized controlled clinical trial.
    François, Bruno Wittebole, Xavier[UCL] Ferrer, Ricard Mira, Jean-Paul Dugernier, Thierry Gibot, Sébastien Derive, Marc Olivier, Aurélie Cuvier, Valérie Witte, Stephan Pickkers, Peter Vandenhende, François Garaud, Jean-Jacques Sánchez, Miguel Salcedo-Magguilli, Margarita Laterre, Pierre-François[UCL] (2020) Intensive care medicine — Vol. 46, no.7, p. 1425-1437 (2020)
    • Article de périodique
    The challenge of ventilator-associated pneumonia diagnosis in COVID-19 patients.
    François, Bruno Laterre, Pierre-François[UCL] Luyt, Charles-Edouard Chastre, Jean (2020) Critical care — Vol. 24, no.1, p. 289 (2020)
    • Article de périodique
    Association of Interleukin 7 Immunotherapy With Lymphocyte Counts Among Patients With Severe Coronavirus Disease 2019 (COVID-19).
    Laterre, Pierre-François[UCL] François, Bruno Collienne, Christine[UCL] Hantson, Philippe[UCL] Jeannet, Robin Remy, Kenneth E Hotchkiss, Richard S (2020) JAMA network open — Vol. 3, no.7, p. e2016485 [1-5] (2020)
    • Article de périodique
    New Agents in Development for Sepsis: Any Reason for Hope?
    Vignon, Philippe Laterre, Pierre-François[UCL] Daix, Thomas François, Bruno (2020) Drugs — Vol. 80, no.17, p. 1751-1761 (2020)
    • Article de périodique
    A phase Ib/IIa, randomised, double-blind, multicentre trial to assess the safety and efficacy of expanded Cx611 allogeneic adipose-derived stem cells (eASCs) for the treatment of patients with community-acquired bacterial pneumonia admitted to the intensive care unit.
    Laterre, Pierre-François[UCL] Sánchez-García, Miguel van der Poll, Tom de la Rosa, Olga Cadogan, Kathy-Ann Lombardo, Eleuterio François, Bruno (2020) BMC pulmonary medicine — Vol. 20, no.1, p. 309 [1-11] (2020)
    • Article de périodique
    Rationale and Design of an Adaptive Phase 2b/3 Clinical Trial of Selepressin for Adults in Septic Shock. Selepressin Evaluation Programme for Sepsis-induced Shock-Adaptive Clinical Trial.
    Lewis, Roger J Angus, Derek C Laterre, Pierre-François[UCL] Kjølbye, Anne Louise van der Meulen, Egbert Blemings, Allan Graves, Todd Russell, James A Carlsen, Jan E Jacobsen, Karsten Yealy, Donald M Opal, Steven M Windeløv, Nis A François, Bruno Perner, Anders Pickkers, Peter Berry, Scott M (2018) Annals of the American Thoracic Society — Vol. 15, no. 2, p. 250-257 (2018)
    • Article de périodique
    Safety and tolerability of non-neutralizing adrenomedullin antibody adrecizumab (HAM8101) in septic shock patients: the AdrenOSS-2 phase 2a biomarker-guided trial.
    Laterre, Pierre-François[UCL] Pickkers, Peter Marx, Gernot Wittebole, Xavier[UCL] Meziani, Ferhat Dugernier, Thierry Huberlant, Vincent Schuerholz, Tobias François, Bruno Lascarrou, Jean-Baptiste Beishuizen, Albertus Oueslati, Haikel Contou, Damien Hoiting, Oscar Lacherade, Jean-Claude Chousterman, Benjamin Pottecher, Julien Bauer, Michael Godet, Thomas Karakas, Mahir Helms, Julie Bergmann, Andreas Zimmermann, Jens Richter, Kathleen Hartmann, Oliver Pars, Melanie Mebazaa, Alexandre AdrenOSS-2 study participants Castanares Zapatero, Diego[UCL] Collienne, Christine[UCL] Gérard, Ludovic[UCL] Hantson, Philippe[UCL] Montiel, Virginie[UCL] Berghe, Caroline[UCL] Dujardin, Marie-France[UCL] Gielens, Leslie[UCL] Renard, Suzanne[UCL] (2021) Intensive care medicine — Vol. 47, no.11, p. 1284-1294 (2021)
    • Article de périodique
    Monitoring circulating dipeptidyl peptidase 3 (DPP3) predicts improvement of organ failure and survival in sepsis: a prospective observational multinational study.
    Blet, Alice Deniau, Benjamin Santos, Karine van Lier, Dirk P T Azibani, Feriel Wittebole, Xavier[UCL] Chousterman, Benjamin G Gayat, Etienne Hartmann, Oliver Struck, Joachim Bergmann, Andreas Antonelli, Massimo Beishuizen, Albertus Constantin, Jean-Michel Damoisel, Charles Deye, Nicolas Di Somma, Salvatore Dugernier, Thierry François, Bruno Gaudry, Stephane Huberlant, Vincent Lascarrou, Jean-Baptiste Marx, Gernot Mercier, Emmanuelle Oueslati, Haikel Pickkers, Peter Sonneville, Romain Legrand, Matthieu Laterre, Pierre-François[UCL] Mebazaa, Alexandre AdrenOSS-1 Study Investigators (2021) Critical care — Vol. 25, no.1, p. 61 [1-10] (2021)
    • Article de périodique
    Efficacy and safety of suvratoxumab for prevention of Staphylococcus aureus ventilator-associated pneumonia (SAATELLITE): a multicentre, randomised, double-blind, placebo-controlled, parallel-group, phase 2 pilot trial.
    François, Bruno Jafri, Hasan S Chastre, Jean Sánchez-García, Miguel Eggimann, Philippe Dequin, Pierre-François Huberlant, Vincent Viña Soria, Lucia Boulain, Thierry Bretonnière, Cédric Pugin, Jérôme Trenado, Josep Hernandez Padilla, Ana Catalina Ali, Omar Shoemaker, Kathryn Ren, Pin Coenjaerts, Frank E Ruzin, Alexey Barraud, Olivier Timbermont, Leen Lammens, Christine Pierre, Vadryn Wu, Yuling Vignaud, Julie Colbert, Susan Bellamy, Terramika Esser, Mark T Dubovsky, Filip Bonten, Marc J Goossens, Herman Laterre, Pierre-François[UCL] COMBACTE Consortium and the SAATELLITE Study Group (2021) The Lancet. Infectious diseases — Vol. 21, no.9, p. 1313-1323 (2021)
    • Article de périodique
    Efficacy and safety of human soluble thrombomodulin (ART-123) for treatment of patients in France with sepsis-associated coagulopathy: post hoc analysis of SCARLET.
    François, Bruno Fiancette, Maud Helms, Julie Mercier, Emmanuelle Lascarrou, Jean-Baptiste Kayanoki, Toshihiko Tanaka, Kosuke Fineberg, David Vincent, Jean-Louis Wittebole, Xavier[UCL] (2021) Annals of intensive care — Vol. 11, no.1, p. 53 [1-8] (2021)
    • Article de périodique
    The Prognostic Value of Brain Dysfunction in Critically Ill Patients with and without Sepsis: A Analysis of the ICON Audit.
    Crippa, Ilaria A Taccone, Fabio S Wittebole, Xavier[UCL] Martin-Loeches, Ignacio Schroeder, Mary E François, Bruno Kotfis, Katarzyna Ñamendys-Silva, Silvio A Forceville, Xavier Solé-Violán, Jordi Fontes, Luis E Vincent, Jean-Louis On Behalf Of The Icon Investigators, (2021) Brain sciences — Vol. 11, no.5, p. 530 [1-10] (2021)
    • Article de périodique
    Temporal changes in the epidemiology, management, and outcome from acute respiratory distress syndrome in European intensive care units: a comparison of two large cohorts.
    Sakr, Yasser François, Bruno Solé-Violan, Jordi Kotfis, Katarzyna Jaschinski, Ulrich Estella, Angel Leone, Marc Jakob, Stephan M Wittebole, Xavier[UCL] Fontes, Luis E de Melo Gurgel, Miguel Midega, Thais Vincent, Jean-Louis Ranieri, V Marco SOAP and ICON Investigators Installé, Etienne[UCL] Dive, Alain-Michel[UCL] (2021) Critical care — Vol. 25, no.1, p. 87 [1-12] (2021)
    • Article de périodique
    Prognostic performance of endothelial biomarkers to early predict clinical deterioration of patients with suspected bacterial infection and sepsis admitted to the emergency department.
    Lafon, Thomas Cazalis, Marie-Angélique Vallejo, Christine Tazarourte, Karim Blein, Sophie Pachot, Alexandre Laterre, Pierre-François[UCL] Laribi, Said François, Bruno TRIAGE study group Verschuren, Franck[UCL] Fabry, Manon[UCL] (2020) Annals of intensive care — Vol. 10, no.1, p. 113 [1-12] (2020)
    • Article de périodique
    Early Corticosteroid Therapy May Increase Ventilator-Associated Lower Respiratory Tract Infection in Critically Ill Patients with COVID-19: A Multicenter Retrospective Cohort Study.
    Mesland, Jean-Baptiste[UCL] Carlier, Eric François, Bruno Serck, Nicolas Gérard, Ludovic[UCL] Briat, Charlotte Piagnerelli, Michael Laterre, Pierre-François[UCL] On Behalf Of The Covcorvap Collaboration Group (2022) Microorganisms — Vol. 10, no.5, p. 984 [1-13] (2022)