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Affichage: 10 résultats.
    • Article de périodique
    Unravelling the Allosteric Targeting of PHGDH at the ACT-Binding Domain with a Photoactivatable Diazirine Probe and Mass Spectrometry Experiments
    Spillier, Quentin[UCL] Ravez, Séverine Dochain Simon[UCL] Vertommen, Didier[UCL] Thabault, Léopold[UCL] Feron, Olivier[UCL] Frédérick, Raphaël[UCL] (2021) Molecules — Vol. 26, no. 2, p. 477 (2021)
    • Article de périodique
    α-Ketothioamide derivatives: a promising tool to interrogate the phosphoglycerate dehydrogenase (PHGDH).
    Ravez, Séverine Corbet, Cyril[UCL] Spillier, Quentin Dutu, Alice Robin, Anita D Mullarky, Edouard Cantley, Lewis Clayton Feron, Olivier[UCL] Frédérick, Raphaël (2017) Journal of Medicinal Chemistry — (2017)
    • Brevet
    Serine biosynthetic pathway inhibitors
    Frédérick, Raphaël[UCL] Ravez, Séverine[UCL] Spillier, Quentin[UCL] Corbet, Cyril[UCL] Feron, Olivier[UCL]
    • Article de périodique
    Challenges and Opportunities in the Development of Serine Synthetic Pathway Inhibitors for Cancer Therapy.
    Ravez, Séverine[UCL] Spillier, Quentin[UCL] Marteau, Romain[UCL] Feron, Olivier[UCL] Frédérick, Raphaël[UCL] (2017) Journal of Medicinal Chemistry — Vol. 60, no. 4, p. 1227-1237 (2017)
    • Communication
    Target the serine synthetic pathway, a promising new anticancer strategy
    Spillier, Quentin[UCL] Ravez, Séverine[UCL] Corbet, Cyril[UCL] Feron, Olivier[UCL] Frédérick, Raphaël[UCL] (2016) ULB Cancer Research Centre (U CRC) opening symposium, Bruxelles, — Brussels, Belgium
    • Communication
    Towards the development of new anti cancer agents targeting the serine synthetic pathway (
    Spillier, Quentin[UCL] Ravez, Séverine[UCL] Corbet, Cyril[UCL] Feron, Olivier[UCL] Frédérick, Raphaël[UCL] (2018) BACR Meeting — Liège, Belgium
    • Communication
    Towards the development of new anti cancer agents targeting the serine synthetic pathway
    Spillier, Quentin[UCL] Ravez, Séverine[UCL] Batista, O MARTEAU, Clément[UCL] Corbet, Cyril[UCL] Feron, Olivier[UCL] Frédérick, Raphaël[UCL] (2016) Télévie Researchers Seminar — Brussels, Belgium
    • Communication
    Design of phosphoglycerate dehydrogenase (PHGDH) inhibitors: A promising target for the development of anticancer agents
    Spillier, Quentin[UCL] Ravez, Séverine[UCL] Corbet, Cyril[UCL] Feron, Olivier[UCL] Frédérick, Raphaël[UCL] (2015) 29ème Journées Franco Belges de Pharmacochimie — Spa, Belgium
    • Article de périodique
    Synthesis and biological evaluation of di-aryl urea derivatives as c-Kit inhibitors
    Ravez, Séverine Arsenlis, Stéphane Barczyk, Amélie Dupont, Anthony Frédérick, Raphaël[UCL] Hesse, Stéphanie Kirsch, Gilbert Depreux, Patrick Goossens, Laurence (2015) Bioorganic & Medicinal Chemistry : the tetrahedron journal for research at the interface of chemistry and biology — Vol. 23, no.22, p. 7340-7347 (2015)
    • Article de périodique
    Repositioning of FDA-Approved antifungal agents to interrogate Acyl-CoA synthetase long chain family member 4 (ACSL4) in ferroptosis
    Marteau, Romain[UCL] Ravez, Séverine Mazhari Dorooee, Darius[UCL] Bouchaoui, Hind Porte, Karine[UCL] Devedjian, Jean-Christophe Melnyk, Patricia Devos, David Frédérick, Raphaël[UCL] El Bakali, Jamal (2022) Biochemical pharmacology — Vol. 204, p. 115239 [1-12] (2022)