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Prebiotic effects: metabolic and health benefits.

  1. YAZAWA KOUHEI, IMAI KAZUHIRO, TAMURA ZENZO, Oligosaccharides and polysaccharides specifically utilizable by Bifidobacteria., 10.1248/cpb.26.3306
  2. Mitsuoka Tomotari, Hidaka Hidemasa, Eida Toshiaki, Effect of fructo-oligosaccharides on intestinal microflora, 10.1002/food.19870310528
  3. Gibson, J Nutr, 125, 1401 (1995)
  4. Gibson Glenn R., Probert Hollie M., Loo Jan Van, Rastall Robert A., Roberfroid Marcel B., Dietary modulation of the human colonic microbiota: updating the concept of prebiotics, 10.1079/nrr200479
  5. Suau, Appl Environ Microbiol, 65, 4799 (1999)
  6. Hermie J. M. Harmsen, Peter Elfferi, A 16S rRNA-targeted Probe for Detection of Lactobacilli and Enterococci in Faecal Samples by FluorescentIn SituHybridization, 10.1080/089106099435862
  7. Harmsen H. J. M., Wildeboer-Veloo A. C. M., Grijpstra J., Knol J., Degener J. E., Welling G. W., Development of 16S rRNA-Based Probes for the Coriobacterium Group and the Atopobium Cluster and Their Application for Enumeration of Coriobacteriaceae in Human Feces from Volunteers of Different Age Groups, 10.1128/aem.66.10.4523-4527.2000
  8. Harmsen H. J. M., Raangs G. C., He T., Degener J. E., Welling G. W., Extensive Set of 16S rRNA-Based Probes for Detection of Bacteria in Human Feces, 10.1128/aem.68.6.2982-2990.2002
  9. Zoetendal, Appl Environ Microbiol, 64, 3854 (1998)
  10. Erwin G. Zoetendal, Antoon D. L. Ak, The Host Genotype Affects the Bacterial Community in the Human Gastronintestinal Tract, 10.1080/089106001750462669
  11. Zoetendal E. G., von Wright A., Vilpponen-Salmela T., Ben-Amor K., Akkermans A. D. L., de Vos W. M., Mucosa-Associated Bacteria in the Human Gastrointestinal Tract Are Uniformly Distributed along the Colon and Differ from the Community Recovered from Feces, 10.1128/aem.68.7.3401-3407.2002
  12. Wang X., Heazlewood S.P., Krause D.O., Florin T.H.J., Molecular characterization of the microbial species that colonize human ileal and colonic mucosa by using 16S rDNA sequence analysis, 10.1046/j.1365-2672.2003.02005.x
  13. Wang Mei, Ahrné Siv, Jeppsson Bengt, Molin Göran, Comparison of bacterial diversity along the human intestinal tract by direct cloning and sequencing of 16S rRNA genes, 10.1016/j.femsec.2005.03.012
  14. Eckburg P. B., Diversity of the Human Intestinal Microbial Flora, 10.1126/science.1110591
  15. Hayashi H., Molecular analysis of jejunal, ileal, caecal and recto-sigmoidal human colonic microbiota using 16S rRNA gene libraries and terminal restriction fragment length polymorphism, 10.1099/jmm.0.45935-0
  16. Green G.L., Brostoff J., Hudspith B., Michael M., Mylonaki M., Rayment N., Staines N., Sanderson J., Rampton D.S., Bruce K.D., Molecular characterization of the bacteria adherent to human colorectal mucosa, 10.1111/j.1365-2672.2005.02783.x
  17. Roberfroid Marcel B., Functional foods: concepts and application to inulin and oligofructose, 10.1079/bjn/2002529
  18. Roberfroid Marcel B., Introducing inulin-type fructans, 10.1079/bjn20041350
  19. Roberfroid, J Nutr, 137, S2489 (2007)
  20. Handbook of Prebiotics, ISBN:9780849381713, 10.1201/9780849381829
  21. Cummings John H., Antoine Jean-Michel, Azpiroz Fernando, Bourdet-Sicard Raphaelle, Brandtzaeg Per, Calder Philip C., Gibson Glenn R., Guarner Francisco, Isolauri Erika, Pannemans Daphne, Shortt Colette, Tuijtelaars Sandra, Watzl Bernhard, PASSCLAIM1?Gut health and immunity, 10.1007/s00394-004-1205-4
  22. Wilson, Appl Environ Microbiol, 62, 2273 (1996)
  23. Kerckhoffs, Gastrointestinal Microbiology, 25 (2006)
  24. O'Connor, Probiotic Dairy Products, 167 (2005)
  25. O'May G. A., Reynolds N., Macfarlane G. T., Effect of pH on an In Vitro Model of Gastric Microbiota in Enteral Nutrition Patients, 10.1128/aem.71.8.4777-4783.2005
  26. Reuter, Curr Issues Intest Microbiol, 2, 43 (2001)
  27. O'May G. A., Reynolds N., Macfarlane G. T., Effect of pH on an In Vitro Model of Gastric Microbiota in Enteral Nutrition Patients, 10.1128/aem.71.8.4777-4783.2005
  28. Macfarlane G.T., Macfarlane S., Gibson G.R., Validation of a Three-Stage Compound Continuous Culture System for Investigating the Effect of Retention Time on the Ecology and Metabolism of Bacteria in the Human Colon, 10.1007/s002489900072
  29. Duncan S. H., Proposal of Roseburia faecis sp. nov., Roseburia hominis sp. nov. and Roseburia inulinivorans sp. nov., based on isolates from human faeces, 10.1099/ijs.0.64098-0
  30. Derrien M., Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium, 10.1099/ijs.0.02873-0
  31. Walker A. W., Duncan S. H., McWilliam Leitch E. C., Child M. W., Flint H. J., pH and Peptide Supply Can Radically Alter Bacterial Populations and Short-Chain Fatty Acid Ratios within Microbial Communities from the Human Colon, 10.1128/aem.71.7.3692-3700.2005
  32. Blaut M., Collins M.D., Welling G. W., Doré J., van Loo J., de Vos W., Molecular biological methods for studying the gut microbiota: the EU human gut flora project, 10.1079/bjn/2002539
  33. Manichanh C, Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach, 10.1136/gut.2005.073817
  34. Stewart J. A, Investigations into the influence of host genetics on the predominant eubacteria in the faecal microflora of children, 10.1099/jmm.0.46189-0
  35. Cherbut Christine, Motor effects of short-chain fatty acids and lactate in the gastrointestinal tract, 10.1079/pns2002213
  36. Flint Harry J., Bayer Edward A., Rincon Marco T., Lamed Raphael, White Bryan A., Polysaccharide utilization by gut bacteria: potential for new insights from genomic analysis, 10.1038/nrmicro1817
  37. Cummings J.H., Macfarlane G.T., The control and consequences of bacterial fermentation in the human colon, 10.1111/j.1365-2672.1991.tb02739.x
  38. Rowland Ian R., Mallett Anthony K., Wise Alan, The Effect of Diet on the Mammalian Gut Flora and Its Metabolic Activities, 10.3109/10408448509041324
  39. Topping, Physiol Rev, 81, 1031 (2001)
  40. Lupton, J Nutr, 134, 479 (2004)
  41. Macfarlane, J Appl Bacteriol, 72, 57 (1992)
  42. Bingham S. A., Pett S., Day K. C., Non-starch polysaccharide intake of a representative sample of British adults, 10.1111/j.1365-277x.1990.tb00244.x
  43. Gray, Dietary Fibre: Definition, Analysis, Physiology and Health (2006)
  44. Englyst Hans N., Macfarlane George T., Breakdown of resistant and readily digestible starch by human gut bacteria, 10.1002/jsfa.2740370717
  45. Hudson, Human Colonic Bacteria: Role in Nutrition, Physiology and Pathology, 61 (1995)
  46. Quigley, Human Colonic Bacteria: Role in Nutrition, Physiology and Pathology, 175 (1995)
  47. Macfarlane, Human Colonic Bacteria: Role in Nutrition, Physiology and Pathology, 75 (1995)
  48. Cummings J H, Short chain fatty acids in the human colon., 10.1136/gut.22.9.763
  49. Cummings, Human Colonic Bacteria: Role in Nutrition, Physiology and Pathology, 101 (1995)
  50. Flint Harry J., The significance of prokaryote diversity in the human gastrointestinal tract, Prokaryotic diversity ISBN:9780511754913 p.65-90, 10.1017/cbo9780511754913.005
  51. Levitt, Human Colonic Bacteria: Role in Nutrition, Physiology and Health, 113 (1995)
  52. Blaut, Eur J Nutr, 1, I11 (2002)
  53. dass n. b., john a. k., bassil a. k., crumbley c. w., shehee w. r., maurio f. p., moore g. b. t., taylor c. m., sanger g. j., The relationship between the effects of short-chain fatty acids on intestinal motility in vitro and GPR43 receptor activation, 10.1111/j.1365-2982.2006.00853.x
  54. Engelhardt, Short-Chain Fatty Acids: Metabolism and Clinical Importance, 60 (1991)
  55. Vogt, J Nutr, 133, 3145 (2003)
  56. Reshef, J Lipid Res, 8, 682 (1967)
  57. Siong, PNAS, 4, 1045 (2004)
  58. Williams Elizabeth A., Coxhead Jonathan M., Mathers John C., Anti-cancer effects of butyrate: use of micro-array technology to investigate mechanisms, 10.1079/pns2002230
  59. Scheppach Wolfgang, , Treatment of distal ulcerative colitis with short-chain fatty acid enemas a placebo-controlled trial, 10.1007/bf02071409
  60. TAMURA Zenzo, Nutriology of Bifidobacteria, 10.12938/bifidus1982.2.1_3
  61. Hughes S. A., Shewry P. R., Li L., Gibson G. R., Sanz M. L., Rastall R. A., In Vitro Fermentation by Human Fecal Microflora of Wheat Arabinoxylans, 10.1021/jf070293g
  62. Wang X., Gibson G.R., Effects of thein vitrofermentation of oligofructose and inulin by bacteria growing in the human large intestine, 10.1111/j.1365-2672.1993.tb02790.x
  63. Rycroft C.E., Jones M.R., Gibson G.R., Rastall R.A., A comparative in vitro evaluation of the fermentation properties of prebiotic oligosaccharides, 10.1046/j.1365-2672.2001.01446.x
  64. Hayakawa K., Mizutani J., Wada K., Masai T., Yoshihara I., Mitsuoka T., Effects of Soybean Oligosaccharides on Human Faecal Flora, 10.3109/08910609009140252
  65. Sghir A., Chow J. M., Mackie R. I., Continuous culture selection of bifidobacteria and lactobacilli from human faecal samples using fructooligosaccharide as selective substrate, 10.1111/j.1365-2672.1998.00590.x
  66. Gibson Glenn R., Wang Xin, Enrichment of bifidobacteria from human gut contents by oligofructose using continuous culture, 10.1111/j.1574-6968.1994.tb06813.x
  67. Gibson G.R., Wang X., Regulatory effects of bifidobacteria on the growth of other colonic bacteria, 10.1111/j.1365-2672.1994.tb03443.x
  68. McBain A. J., Macfarlane G. T., Investigations of Bifidobacterial Ecology and Oligosaccharide Metabolism in a Three-Stage Compound Continuous Culture System, 10.1080/00365521.1997.11720715
  69. McBAIN A.J., MACFARLANE G.T., Modulation of genotoxic enzyme activities by non-digestible oligosaccharide metabolism in in-vitro human gut bacterial ecosystems, 10.1099/0022-1317-50-9-833
  70. Wada, J Agric Chem Soc Japan, 66, 127 (1992)
  71. Palframan Richard J., Gibson Glenn R., Rastall Robert A., Effect of pH and Dose on the Growth of Gut Bacteria on Prebiotic Carbohydrates in vitro, 10.1006/anae.2002.0434
  72. Tzortzis, In Vivo J Nutr, 135, 1726 (2005)
  73. Wiele Tom, Boon Nico, Possemiers Sam, Jacobs Heidi, Verstraete Willy, Prebiotic effects of chicory inulin in the simulator of the human intestinal microbial ecosystem, 10.1016/j.femsec.2004.07.014
  74. van de Wiele T., Boon N., Possemiers S., Jacobs H., Verstraete W., Inulin-type fructans of longer degree of polymerization exert more pronounced in vitro prebiotic effects, 10.1111/j.1365-2672.2006.03084.x
  75. Minekus M., Smeets-Peeters M., Bernalier A., Marol-Bonnin S., Havenaar R., Marteau P., Alric M., Fonty G., Huis in't Veld J. H. J., A computer-controlled system to simulate conditions of the large intestine with peristaltic mixing, water absorption and absorption of fermentation products, 10.1007/s002530051622
  76. Venema Koen, van Nuenen Marleen H.M.C., van den Heuvel Ellen G., Pool Wietske, van der Vossen Jos M.B.M., The Effect of Lactulose on the Composition of the Intestinal Microbiota and Short-chain Fatty Acid Production in Human Volunteers and a Computer-controlled Model of the Proximal Large Intestine, 10.1080/08910600310019895
  77. Roberfroid, Inulin-Type Fructans. Functional Food Ingredients (2005)
  78. Murphy, Janeway's Immunobiology (2007)
  79. Albers Ruud, Antoine Jean-Michel, Bourdet-Sicard Raphaëlle, Calder Philip C., Gleeson Michael, Lesourd Bruno, Samartín Sonia, Sanderson Ian R., Van Loo Jan, Vas Dias F. Willem, Watzl Bernhard, Markers to measure immunomodulation in human nutrition intervention studies, 10.1079/bjn20051469
  80. Wagner Robert Doug, Effects of Microbiota on GI Health: Gnotobiotic Research, Advances in Experimental Medicine and Biology ISBN:9780387799896 p.41-56, 10.1007/978-0-387-09550-9_4
  81. Kelly Denise, King Timothy, Aminov Rustam, Importance of microbial colonization of the gut in early life to the development of immunity, 10.1016/j.mrfmmm.2007.03.011
  82. Round June L., Mazmanian Sarkis K., The gut microbiota shapes intestinal immune responses during health and disease, 10.1038/nri2515
  83. Gaboriau-Routhiau Valérie, Rakotobe Sabine, Lécuyer Emelyne, Mulder Imke, Lan Annaïg, Bridonneau Chantal, Rochet Violaine, Pisi Annamaria, De Paepe Marianne, Brandi Giovanni, Eberl Gérard, Snel Johannes, Kelly Denise, Cerf-Bensussan Nadine, The Key Role of Segmented Filamentous Bacteria in the Coordinated Maturation of Gut Helper T Cell Responses, 10.1016/j.immuni.2009.08.020
  84. Rescigno Maria, Urbano Matteo, Valzasina Barbara, Francolini Maura, Rotta Gianluca, Bonasio Roberto, Granucci Francesca, Kraehenbuhl Jean-Pierre, Ricciardi-Castagnoli Paola, 10.1038/86373
  85. Sanderson, J Nutr, 137, 2557S (2007)
  86. Artis David, Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut, 10.1038/nri2316
  87. Medzhitov Ruslan, Recognition of microorganisms and activation of the immune response, 10.1038/nature06246
  88. Vance Russell E., Isberg Ralph R., Portnoy Daniel A., Patterns of Pathogenesis: Discrimination of Pathogenic and Nonpathogenic Microbes by the Innate Immune System, 10.1016/j.chom.2009.06.007
  89. Rakoff-Nahoum Seth, Paglino Justin, Eslami-Varzaneh Fatima, Edberg Stephen, Medzhitov Ruslan, Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis, 10.1016/j.cell.2004.07.002
  90. Nilsson Niclas E, Kotarsky Knut, Owman Christer, Olde Björn, Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids, 10.1016/s0006-291x(03)00488-1
  91. Le Poul Emmanuel, Loison Cécile, Struyf Sofie, Springael Jean-Yves, Lannoy Vincent, Decobecq Marie-Eve, Brezillon Stéphane, Dupriez Vincent, Vassart Gilbert, Van Damme Jo, Parmentier Marc, Detheux Michel, Functional Characterization of Human Receptors for Short Chain Fatty Acids and Their Role in Polymorphonuclear Cell Activation, 10.1074/jbc.m301403200
  92. Karaki Shin-ichiro, Tazoe Hideaki, Hayashi Hisayoshi, Kashiwabara Hidefumi, Tooyama Kazunari, Suzuki Yuichi, Kuwahara Atsukazu, Expression of the short-chain fatty acid receptor, GPR43, in the human colon, 10.1007/s10735-007-9145-y
  93. Tazoe Hideaki, Otomo Yasuko, Karaki Shin-ichiro, Kato Ikuo, Fukami Yasuyuki, Terasaki Masaki, Kuwahara Atsukazu, Expression of short-chain fatty acid receptor GPR41 in the human colon, 10.2220/biomedres.30.149
  94. Cavaglieri Claudia R, Nishiyama Anita, Fernandes Luis Claudio, Curi Rui, Miles Elizabeth A, Calder Philip C, Differential effects of short-chain fatty acids on proliferation and production of pro- and anti-inflammatory cytokines by cultured lymphocytes, 10.1016/s0024-3205(03)00490-9
  95. Maslowski Kendle M., Vieira Angelica T., Ng Aylwin, Kranich Jan, Sierro Frederic, Di Yu, Schilter Heidi C., Rolph Michael S., Mackay Fabienne, Artis David, Xavier Ramnik J., Teixeira Mauro M., Mackay Charles R., Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43, 10.1038/nature08530
  96. Schley P. D., Field C. J., The immune-enhancing effects of dietary fibres and prebiotics, 10.1079/bjn/2002541
  97. Watzl Bernhard, Girrbach Stephanie, Roller Monika, Inulin, oligofructose and immunomodulation, 10.1079/bjn20041357
  98. Seifert, J Nutr, 137, 2563S (2007)
  99. Lomax Amy R., Calder Philip C., Prebiotics, immune function, infection and inflammation: a review of the evidence, 10.1017/s0007114508055608
  100. Seifert Stephanie, Watzl Bernhard, Prebiotics and the Immune System : Review of Experimental and Human Data, Handbook of Prebiotics (2008) ISBN:9780849381713 p.143-162, 10.1201/9780849381829.ch8
  101. Bunout D, Hirsch S, de la Maza MP, Munoz C, Haschke F, Steenhout P, Klassen P, Barrera G, Gattas V, Petermann M, Effects of prebiotics on the immune response to vaccination in the elderly, 10.1177/0148607102026006372
  102. Bunout D, Barrera G, Hirsch S, Gattas V, de la Maza MP, Haschke F, Steenhout P, Klassen P, Hager C, Avendano M, Petermann M, Munoz C, Effects of a nutritional supplement on the immune response and cytokine production in free-living Chilean elderly, 10.1177/0148607104028005348
  103. Duggan, Am J Clin Nutr, 77, 937 (2003)
  104. van Hoffen E., Ruiter B., Faber J., M'Rabet L., Knol E.F., Stahl B., Arslanoglu S., Moro G., Boehm G., Garssen J., A specific mixture of short-chain galacto-oligosaccharides and long-chain fructo-oligosaccharides induces a beneficial immunoglobulin profile in infants at high risk for allergy, 10.1111/j.1398-9995.2008.01765.x
  105. Bakker-Zierikzee A. M., Tol E. A. F., Kroes H., Alles M. S., Kok F. J., Bindels J. G., Faecal SIgA secretion in infants fed on pre- or probiotic infant formula, 10.1111/j.1399-3038.2005.00370.x
  106. Scholtens, J Nutr, 138, 1141 (2008)
  107. Guigoz Y, Rochat F, Perruisseau-Carrier G, Rochat I, Schiffrin E.J, Effects of oligosaccharide on the faecal flora and non-specific immune system in elderly people, 10.1016/s0271-5317(01)00354-2
  108. Shadid, Am J Clin Nutr, 86, 1426 (2007)
  109. Vulevic, Am J Clin Nutr, 88, 1438 (2008)
  110. Lindsay J O, Clinical, microbiological, and immunological effects of fructo-oligosaccharide in patients with Crohn's disease, 10.1136/gut.2005.074971
  111. Hoentjen Frank, Welling Gjalt W., Harmsen Hermie J. M., Zhang Xiaoyin, Snart Jennifer, Tannock Gerald W, Lien Kelvin, Churchill Thomas A, Lupicki Maryla, Dieleman Levinus A, Reduction of Colitis by Prebiotics in HLA-B27 Transgenic Rats Is Associated with Microflora Changes and Immunomodulation : , 10.1097/01.mib.0000183421.02316.d5
  112. Moro G, A mixture of prebiotic oligosaccharides reduces the incidence of atopic dermatitis during the first six months of age, 10.1136/adc.2006.098251
  113. Fukasawa Tomoyuki, Murashima Koichiro, Matsumoto Ichiro, Hosono Akira, Ohara Hiroki, Nojiri Chuhei, Koga Jinnichiro, Kubota Hidetoshi, Kanegae Minoru, Kaminogawa Shuichi, Abe Keiko, Kono Toshiaki, Identification of Marker Genes for Intestinal Immunomodulating Effect of a Fructooligosaccharide by DNA Microarray Analysis, 10.1021/jf062814q
  114. Roller Monika, Femia Angelo Pietro, Caderni Giovanna, Rechkemmer Gerhard, Watzl Bernhard, Intestinal immunity of rats with colon cancer is modulated by oligofructose-enriched inulin combined with Lactobacillus rhamnosus and Bifidobacterium lactis, 10.1079/bjn20041289
  115. Roller, J Nutr, 134, 153 (2004)
  116. Girrbach, FASEB J, 19, A444 (2005)
  117. Agostoni Carlo, Axelsson Irene, Goulet Olivier, Koletzko Berthold, Michaelsen Kim F., Puntis John W. L., Rigo Jacques, Shamir Raanan, Szajewska Hania, Turck Dominique, Prebiotic Oligosaccharides in Dietetic Products for Infants: A Commentary by the ESPGHAN Committee on Nutrition : , 10.1097/00005176-200411000-00003
  118. Boehm, J Nutr, 138, 1818S (2008)
  119. K.W. Yap Wendy, Mohamed Suhaila, Husni Jamal Mohammad, Diederick Meyer, A. Manap Yazid, Changes in Infants Faecal Characteristics and Microbiota by Inulin Supplementation, 10.3164/jcbn.2008055
  120. Ben, Chin Med J (Engl), 117, 927 (2004)
  121. Ben Xiao-Ming, Low level of galacto-oligosaccharide in infant formula stimulates growth of intestinal Bifidobacteria and Lactobacilli, 10.3748/wjg.14.6564
  122. Fanaro Silvia, Marten Berit, Bagna Rossana, Vigi Vittorio, Fabris Claudio, Peña-Quintana Luis, Argüelles Federico, Scholz-Ahrens Katharina E, Sawatzki Günther, Zelenka Richard, Schrezenmeir Jürgen, de Vrese Michael, Bertino Enrico, Galacto-oligosaccharides Are Bifidogenic and Safe at Weaning: A Double-blind Randomized Multicenter Study : , 10.1097/mpg.0b013e31817b6dd2
  123. Magne Fabien, Hachelaf Wahiba, Suau Antonia, Boudraa Ghazalia, Bouziane-Nedjadi Karim, Rigottier-Gois Lionel, Touhami Mahmoud, Desjeux Jehan-François, Pochart Philippe, Effects on Faecal Microbiota of Dietary and Acidic Oligosaccharides in Children During Partial Formula Feeding : , 10.1097/mpg.0b013e318164d920
  124. Official J Eur Union, L401, 1 (2006)
  125. Moore Nancy, Chao Cewin, Yang Li-Ping, Storm Heidi, Oliva-Hemker Maria, Saavedra Jose M., Effects of fructo-oligosaccharide-supplemented infant cereal: a double-blind, randomized trial, 10.1079/bjn2003950
  126. Scholtens Petra A.M.J., Alles Martine S., Bindels Jacques G., van der Linde Esmeralda G.M., Tolboom Jules J.M., Knol Jan, Bifidogenic Effects of Solid Weaning Foods With Added Prebiotic Oligosaccharides : A Randomised Controlled Clinical Trial, 10.1097/01.mpg.0000221887.28877.c7
  127. Lien do, Asia Pac J Clin Nutr, 18, 326 (2009)
  128. Bruzzese Eugenia, Volpicelli Monica, Squeglia Veronica, Bruzzese Dario, Salvini Filippo, Bisceglia Massimo, Lionetti Paolo, Cinquetti Mario, Iacono Giuseppe, Amarri Sergio, Guarino Alfredo, A formula containing galacto- and fructo-oligosaccharides prevents intestinal and extra-intestinal infections: An observational study, 10.1016/j.clnu.2009.01.008
  129. Arslanoglu, J Nutr, 137, 2420 (2007)
  130. Hoekstra J. H., Szajewska H., Zikri M. Abu, Micetic-Turk D., Weizman Z., Papadopoulou A., Guarino A., Dias J. A., Oostvogels B., Oral Rehydration Solution Containing a Mixture of Non-Digestible Carbohydrates in the Treatment of Acute Diarrhea: A Multicenter Randomized Placebo Controlled Study on Behalf of the ESPGHAN Working Group on Intestinal Infections : , 10.1097/00005176-200409000-00003
  131. Surawicz Christina M, Probiotics, antibiotic-associated diarrhoea and Clostridium difficile diarrhoea in humans, 10.1016/s1521-6918(03)00054-4
  132. D'Souza A. L, Probiotics in prevention of antibiotic associated diarrhoea: meta-analysis, 10.1136/bmj.324.7350.1361
  133. Cremonini F., Di Caro S., Nista E. C., Bartolozzi F., Capelli G., Gasbarrini G., Gasbarrini A., Meta-analysis: the effect of probiotic administration on antibiotic-associated diarrhoea, 10.1046/j.1365-2036.2002.01318.x
  134. SZAJEWSKA H., MRUKOWICZ J., Meta-analysis: non-pathogenic yeast Saccharomyces boulardii in the prevention of antibiotic-associated diarrhoea, 10.1111/j.1365-2036.2005.02624.x
  135. Hawrelak Jason A., Whitten Dawn L., Myers Stephen P., Is Lactobacillus rhamnosus GG Effective in Preventing the Onset of Antibiotic-Associated Diarrhoea: A Systematic Review, 10.1159/000087637
  136. Szajewska Hania, Ruszczyński Marek, Radzikowski Andrzej, Probiotics in the prevention of antibiotic-associated diarrhea in children: A meta-analysis of randomized controlled trials, 10.1016/j.jpeds.2006.04.053
  137. Brunser Oscar, Gotteland Martin, Cruchet Sylvia, Figueroa Guillermo, Garrido Daniel, Steenhout Philippe, Effect of a Milk Formula With Prebiotics on the Intestinal Microbiota of Infants After an Antibiotic Treatment, 10.1203/01.pdr.0000198773.40937.61
  138. Kalliomäki Marko, Kirjavainen Pirkka, Eerola Erkki, Kero Pentti, Salminen Seppo, Isolauri Erika, Distinct patterns of neonatal gut microflora in infants in whom atopy was and was not developing, 10.1067/mai.2001.111237
  139. Arslanoglu, J Nutr, 138, 1091 (2008)
  140. Cummings J. H., Christie S., Cole T. J., A study of fructo oligosaccharides in the prevention of travellers' diarrhoea, 10.1046/j.1365-2036.2001.01043.x
  141. Lewis S., Burmeister S., Cohen S., Brazier J., Awasthi A., Failure of dietary oligofructose to prevent antibiotic-associated diarrhoea, 10.1111/j.1365-2036.2005.02304.x
  142. Lewis Stephen, Burmeister Stephen, Brazier Jon, Effect of the Prebiotic Oligofructose on Relapse of Clostridium difficile-Associated Diarrhea: A Randomized, Controlled Study, 10.1016/s1542-3565(04)00677-9
  143. Spiller R, Aziz Q, Creed F, Emmanuel A, Houghton L, Hungin P, Jones R, Kumar D, Rubin G, Trudgill N, Whorwell P, Guidelines on the irritable bowel syndrome: mechanisms and practical management, 10.1136/gut.2007.119446
  144. Longstreth George F., Thompson W. Grant, Chey William D., Houghton Lesley A., Mearin Fermin, Spiller Robin C., Functional Bowel Disorders, 10.1053/j.gastro.2005.11.061
  145. Serra Jordi, Salvioli Beatrice, Azpiroz Fernando, Malagelada Juan–R., Lipid-induced intestinal gas retention in irritable bowel syndrome, 10.1053/gast.2002.35394
  146. SPILLER R., Review article: probiotics and prebiotics in irritable bowel syndrome, 10.1111/j.1365-2036.2008.03750.x
  147. Balsari, Microbiologica, 5, 185 (1982)
  148. Si Jian-Min, Intestinal microecology and quality of life in irritable bowel syndrome patients, 10.3748/wjg.v10.i12.1802
  149. Malinen Erja, Rinttila Teemu, Kajander Kajsa, Matto Jaana, Kassinen Anna, Krogius Lotta, Saarela Maria, Korpela Riitta, Palva Airi, Analysis of the Fecal Microbiota of Irritable Bowel Syndrome Patients and Healthy Controls with Real-Time PCR, 10.1111/j.1572-0241.2005.40312.x
  150. Chassard, Reprod Nutr Develop, S4 (2006)
  151. Kassinen Anna, Krogius-Kurikka Lotta, Mäkivuokko Harri, Rinttilä Teemu, Paulin Lars, Corander Jukka, Malinen Erja, Apajalahti Juha, Palva Airi, The Fecal Microbiota of Irritable Bowel Syndrome Patients Differs Significantly From That of Healthy Subjects, 10.1053/j.gastro.2007.04.005
  152. Kerckhoffs Angèle PM, LowerBifidobacteriacounts in both duodenal mucosa-associated and fecal microbiota in irritable bowel syndrome patients, 10.3748/wjg.15.2887
  153. Maukonen J., Prevalence and temporal stability of selected clostridial groups in irritable bowel syndrome in relation to predominant faecal bacteria, 10.1099/jmm.0.46134-0
  154. Nyman M., Fermentation and bulking capacity of indigestible carbohydrates: the case of inulin and oligofructose, 10.1079/bjn/2002533
  155. DE PRETER V., VANHOUTTE T., HUYS G., SWINGS J., RUTGEERTS P., VERBEKE K., Baseline microbiota activity and initial bifidobacteria counts influence responses to prebiotic dosing in healthy subjects : RESPONSES TO PREBIOTIC DOSING OF COLONIC FLORA, 10.1111/j.1365-2036.2007.03588.x
  156. Furrie E, Synbiotic therapy (Bifidobacterium longum/Synergy 1) initiates resolution of inflammation in patients with active ulcerative colitis: a randomised controlled pilot trial, 10.1136/gut.2004.044834
  157. CASELLAS F., BORRUEL N., TORREJÓN A., VARELA E., ANTOLIN M., GUARNER F., MALAGELADA J.-R., Oral oligofructose-enriched inulin supplementation in acute ulcerative colitis is well tolerated and associated with lowered faecal calprotectin : INULIN SUPPLEMENTATION IN ACUTE ULCERATIVE COLITIS, 10.1111/j.1365-2036.2007.03288.x
  158. Cook Karon F., Rabeneck Linda, Campbell Catherine J.M., Wray Nelda P., Evaluation of a Multidimensional Measure of Dyspepsia-Related Health for Use in a Randomized Clinical Trial, 10.1016/s0895-4356(99)00018-9
  159. Olesen, Am J Clin Nutr, 72, 1570 (2000)
  160. Hunter, J Nutr, 129, 1451S (1999)
  161. Irvine, Gastroenterology, 133, 24 (2006)
  162. Dughera, Acta Biomed, 78, 111 (2007)
  163. Paineau Damien, Payen Flore, Panserieu Suzanne, Coulombier Geneviève, Sobaszek Annie, Lartigau Isabelle, Brabet Marylène, Galmiche Jean-Paul, Tripodi Dominique, Sacher-Huvelin Sylvie, Chapalain Véronique, Zourabichvili Othar, Respondek Frédérique, Wagner Anne, Bornet Francis R. J., The effects of regular consumption of short-chain fructo-oligosaccharides on digestive comfort of subjects with minor functional bowel disorders, 10.1017/s000711450779894x
  164. SILK D. B. A., DAVIS A., VULEVIC J., TZORTZIS G., GIBSON G. R., Clinical trial: the effects of a trans-galactooligosaccharide prebiotic on faecal microbiota and symptoms in irritable bowel syndrome, 10.1111/j.1365-2036.2008.03911.x
  165. Loftus Edward V, Clinical epidemiology of inflammatory bowel disease: incidence, prevalence, and environmental influences, 10.1053/j.gastro.2004.01.063
  166. Travis S P L, European evidence based consensus on the diagnosis and management of Crohn's disease: current management, 10.1136/gut.2005.081950b
  167. Lucendo Alfredo José, Importance of nutrition in inflammatory bowel disease, 10.3748/wjg.15.2081
  168. Irvine, Am J Gastroenterol, 92, 18S (1997)
  169. Schwartz Marc, Cohen Russell, Optimizing conventional therapy for inflammatory bowel disease, 10.1007/s11894-008-0106-8
  170. Carter M J, Guidelines for the management of inflammatory bowel disease in adults, 10.1136/gut.2004.043372
  171. Teahon Kathy, Pearson Morag, Levi A. Jonathan, Bjarnason Ingvar, Practical Aspects of Enteral Nutrition in the Management of Crohn's Disease, 10.1177/0148607195019005365
  172. Neuman Manuela G., Immune dysfunction in inflammatory bowel disease, 10.1016/j.trsl.2006.11.009
  173. Lindsay J. O., Hodgson H. J. F., The immunoregulatory cytokine interleukin-10-a therapy for Crohn's disease?, 10.1046/j.1365-2036.2001.01093.x
  174. Brown Steven J., Mayer Lloyd, The Immune Response in Inflammatory Bowel Disease, 10.1111/j.1572-0241.2007.01343.x
  175. Sellon, Infect Immun, 66, 5224 (1998)
  176. Fasoli R., Kettlewell M. G. W., Mortensen N., Jewell D. P., Response to faecal challenge in defunctioned colonic Crohn's disease: prediction of long-term course, 10.1002/bjs.1800770606
  177. Chichlowski M., Hale L. P., Bacterial-mucosal interactions in inflammatory bowel disease--an alliance gone bad, 10.1152/ajpgi.90516.2008
  178. Hugot Jean-Pierre, Chamaillard Mathias, Zouali Habib, Lesage Suzanne, Cézard Jean-Pierre, Belaiche Jacques, Almer Sven, Tysk Curt, O'Morain Colm A., Gassull Miquel, Binder Vibeke, Finkel Yigael, Cortot Antoine, Modigliani Robert, Laurent-Puig Pierre, Gower-Rousseau Corine, Macry Jeanne, Colombel Jean-Frédéric, Sahbatou Mourad, Thomas Gilles, 10.1038/35079107
  179. Zhang H., Massey D., Tremelling M., Parkes M., Genetics of inflammatory bowel disease: clues to pathogenesis, 10.1093/bmb/ldn031
  180. Miyauchi E., Morita H., Tanabe S., Lactobacillus rhamnosus alleviates intestinal barrier dysfunction in part by increasing expression of zonula occludens-1 and myosin light-chain kinase in vivo, 10.3168/jds.2008-1698
  181. Garcia Vilela Eduardo, De Lourdes De Abreu Ferrari Maria, Oswaldo Da Gama Torres Henrique, Guerra Pinto Ademar, Carolina Carneiro Aguirre Ana, Paiva Martins Fabiana, Marcos Andrade Goulart Eugênio, Sales Da Cunha Aloísio, Influence ofSaccharomyces boulardiion the intestinal permeability of patients with Crohn's disease in remission, 10.1080/00365520801943354
  182. Hart A L, Modulation of human dendritic cell phenotype and function by probiotic bacteria, 10.1136/gut.2003.037325
  183. Ng, Gut, 57, A37 (2008)
  184. Sartor R. Balfour, Microbial Influences in Inflammatory Bowel Diseases, 10.1053/j.gastro.2007.11.059
  185. Hedin Charlotte, Whelan Kevin, Lindsay James O., Evidence for the use of probiotics and prebiotics in inflammatory bowel disease: a review of clinical trials, 10.1017/s0029665107005563
  186. Seksik P, Alterations of the dominant faecal bacterial groups in patients with Crohn's disease of the colon, 10.1136/gut.52.2.237
  187. Sokol H., Seksik P., Furet J. P., Firmesse O., Nion-Larmurier I., Beaugerie L., Cosnes J., Corthier G., Marteau P., Doré J., Low counts of Faecalibacterium prausnitzii in colitis microbiota : , 10.1002/ibd.20903
  188. Macfarlane S., Furrie E., Cummings J. H., Macfarlane G. T., Chemotaxonomic Analysis of Bacterial Populations Colonizing the Rectal Mucosa in Patients with Ulcerative Colitis, 10.1086/420823
  189. Mylonaki Maria, Rayment Neil B, Rampton David S, Hudspith Barry N, Brostoff Jonathan, Molecular Characterization of Rectal Mucosa-Associated Bacterial Flora in Inflammatory Bowel Disease : , 10.1097/01.mib.0000159663.62651.4f
  190. Swidsinski Alexander, Ladhoff Axel, Pernthaler Annelie, Swidsinski Sonja, Loening–Baucke Vera, Ortner Marianne, Weber Jutta, Hoffmann Uwe, Schreiber Stefan, Dietel Manfred, Lochs Herbert, Mucosal flora in inflammatory bowel disease, 10.1053/gast.2002.30294
  191. Frank D. N., St. Amand A. L., Feldman R. A., Boedeker E. C., Harpaz N., Pace N. R., Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases, 10.1073/pnas.0706625104
  192. Sokol H., Lepage P., Seksik P., Dore J., Marteau P., Temperature Gradient Gel Electrophoresis of Fecal 16S rRNA Reveals Active Escherichia coli in the Microbiota of Patients with Ulcerative Colitis, 10.1128/jcm.02600-05
  193. Martinez-Medina Margarita, Aldeguer Xavier, Gonzalez-Huix Ferran, Acero Doroteo, Garcia-Gil Jesús L., Abnormal microbiota composition in the ileocolonic mucosa of Crohnʼs disease patients as revealed by polymerase chain reaction-denaturing gradient gel electrophoresis : , 10.1097/01.mib.0000235828.09305.0c
  194. Sokol H., Pigneur B., Watterlot L., Lakhdari O., Bermudez-Humaran L. G., Gratadoux J.-J., Blugeon S., Bridonneau C., Furet J.-P., Corthier G., Grangette C., Vasquez N., Pochart P., Trugnan G., Thomas G., Blottiere H. M., Dore J., Marteau P., Seksik P., Langella P., Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients, 10.1073/pnas.0804812105
  195. Kolida, J Nutr, 137, 2503S (2007)
  196. Langlands S J, Prebiotic carbohydrates modify the mucosa associated microflora of the human large bowel, 10.1136/gut.2003.037580
  197. Ramirez-Farias Carlett, Slezak Kathleen, Fuller Zoë, Duncan Alan, Holtrop Grietje, Louis Petra, Effect of inulin on the human gut microbiota: stimulation of Bifidobacterium adolescentis and Faecalibacterium prausnitzii, 10.1017/s0007114508019880
  198. Burger-van Paassen Nanda, Vincent Audrey, Puiman Patrycja J., van der Sluis Maria, Bouma Janneke, Boehm Günther, van Goudoever Johannes B., van Seuningen Isabelle, Renes Ingrid B., The regulation of intestinal mucin MUC2 expression by short-chain fatty acids: implications for epithelial protection, 10.1042/bj20082222
  199. Pullan R D, Thomas G A, Rhodes M, Newcombe R G, Williams G T, Allen A, Rhodes J, Thickness of adherent mucus gel on colonic mucosa in humans and its relevance to colitis., 10.1136/gut.35.3.353
  200. Leenen, J Nutr, 137, 2572S (2007)
  201. Hedin C. R. H., Graczer M., Sanderson J. D., Lindsay J. O., Whelan K., Probiotic and prebiotic use by patients with inflammatory bowel disease, 10.1017/s0029665109001773
  202. Friedman Gerald, George James, Treatment of refractory “Pouchitis” with prebiotic and probiotic therapy, 10.1016/s0016-5085(00)85255-5
  203. Welters Carlo F. M., Heineman Erik, Thunnissen Frederik B. J. M., van den Bogaard Anthony E. J. M., Soeters Peter B., Baeten Cor G. M. I., Effect of Dietary Inulin Supplementation on Inflammation of Pouch Mucosa in Patients With an Ileal Pouch-Anal Anastomosis : , 10.1007/s10350-004-6257-2
  204. Kanauchi, Int J Mol Med, 12, 701 (2003)
  205. Hanai, Int J Mol Med, 13, 643 (2004)
  206. Fujimori Shunji, Gudis Katya, Mitsui Keigo, Seo Tsuguhiko, Yonezawa Masaoki, Tanaka Shu, Tatsuguchi Atsushi, Sakamoto Choitsu, A randomized controlled trial on the efficacy of synbiotic versus probiotic or prebiotic treatment to improve the quality of life in patients with ulcerative colitis, 10.1016/j.nut.2008.11.017
  207. Hussey, J Pediatr Gastroenterol Nutr, 37 (2003)
  208. Benjamin, Gut, 59 (2010)
  209. Chermesh Irit, Tamir Ada, Reshef Ron, Chowers Yehuda, Suissa Alain, Katz Dalia, Gelber Moshe, Halpern Zamir, Bengmark Stig, Eliakim Rami, Failure of Synbiotic 2000 to Prevent Postoperative Recurrence of Crohn’s Disease, 10.1007/s10620-006-9549-7
  210. Su Chinyu, Lewis James D., Goldberg Brittany, Brensinger Colleen, Lichtenstein Gary R., A Meta-Analysis of the Placebo Rates of Remission and Response in Clinical Trials of Active Ulcerative Colitis, 10.1053/j.gastro.2006.12.037
  211. Su Chinyu, Lichtenstein Gary R., Krok Karen, Brensinger Colleen M., Lewis James D., A meta-analysis of the placebo rates of remission and response in clinical trials of active crohn’s disease, 10.1053/j.gastro.2004.01.024
  212. Food, Nutrition, Physical Activity, and the Prevention of Cancer: A Global Perspective (2007)
  213. Rowland Ian, The Role of the Gastrointestinal Microbiota in Colorectal Cancer, 10.2174/138161209788168191
  214. Hughes, Gut Flora, Nutrition, Immunity and Health, 208 (2003)
  215. Rowland, Human Colonic Bacteria, Role in Nutrition, Physiology and Pathology, 155 (1995)
  216. Saito Yoshio, Takano Toshiaki, Rowland Ian, Effects of Soybean Oligosaccharides on the Human Gut Microflora inIn vitroCulture, 10.3109/08910609209141296
  217. Reddy, Cancer Res, 53, 3914 (1993)
  218. Rowland I., Effect of Bifidobacterium longum and inulin on gut bacterial metabolism and carcinogen-induced aberrant crypt foci in rats, 10.1093/carcin/19.2.281
  219. HIDAKA Hidemasa, EIDA Toshiaki, TAKIZAWA Toshio, TOKUNAGA Takahisa, TASHIRO Yasuhito, Effects of Fructooligosaccharides on Intestinal Flora and Human Health, 10.12938/bifidus1982.5.1_37
  220. Rowland I.R., Tanaka R., The effects of transgalactosylated oligosaccharides on gut flora metabolism in rats associated with a human faecal microflora, 10.1111/j.1365-2672.1993.tb05201.x
  221. TANAKA Ryuichiro, TAKAYAMA Hiroo, MOROTOMI Masami, KUROSHIMA Toshikata, UEYAMA Sadao, MATSUMOTO Keisuke, KURODA Akio, MUTAI Masahiko, Effects of Administration of TOS and Bifidobacterium breve 4006 on the Human Fecal Flora, 10.12938/bifidus1982.2.1_17
  222. Gostner A., Blaut M., Schäffer V., Kozianowski G., Theis S., Klingeberg M., Dombrowski Y., Martin D., Ehrhardt S., Taras D., Schwiertz A., Kleessen B., Lührs H., Schauber J., Dorbath D., Menzel T., Scheppach W., Effect of isomalt consumption on faecal microflora and colonic metabolism in healthy volunteers, 10.1079/bjn20051589
  223. Pretlow Theresa P., O'Riordan Mary Ann, Somich Gregory A., Amini Saeid B., Pretlow Thomas G., Aberrant crypts correlate with tumor incidence in F344 rats treated with azoxymethane and phytate, 10.1093/carcin/13.9.1509
  224. Rao C., Prevention of colonic aberrant crypt foci and modulation of large bowel microbial activity by dietary coffee fiber, inulin and pectin, 10.1093/carcin/19.10.1815
  225. Gallaher, J Nutr, 126, 1362 (1996)
  226. Verghese, J Nutr, 132, 2804 (2002)
  227. Reddy B., Effect of dietary oligofructose and inulin on colonic preneoplastic aberrant crypt foci inhibition, 10.1093/carcin/18.7.1371
  228. Buddington, J Nutr, 132, 472 (2002)
  229. Poulsen Morten, Mølck Anne-Marie, Jacobsen Bodil Lund, Different Effects of Short- and Long-Chained Fructans on Large Intestinal Physiology and Carcinogen-Induced Aberrant Crypt Foci in Rats, 10.1207/s15327914nc422_8
  230. Jacobsen Helene, Poulsen Morten, Ove Dragsted Lars, Ravn-Haren Gitte, Meyer Otto, Hvid Lindecrona Rikke, Carbohydrate Digestibility Predicts Colon Carcinogenesis in Azoxymethane-Treated Rats, 10.1207/s15327914nc5502_7
  231. Caderni, Cancer Res, 63, 2388 (2003)
  232. Challa A, Bifidobacterium longum and lactulose suppress azoxymethane-induced colonic aberrant crypt foci in rats, 10.1093/carcin/18.3.517
  233. Hsu, J Nutr, 134, 1523 (2004)
  234. Wijnands M.V.W., Effect of dietary galacto-oligosaccharides on azoxymethane-induced aberrant crypt foci and colorectal cancer in Fischer 344 rats, 10.1093/carcin/22.1.127
  235. Nakanishi Shuusuke, Kataoka Keiko, Kuwahara Tomomi, Ohnishi Yoshinari, Effects of High Amylose Maize Starch andClostridium butyricumon Metabolism in Colonic Microbiota and Formation of Azoxymethane-Induced Aberrant Crypt Foci in the Rat Colon, 10.1111/j.1348-0421.2003.tb03469.x
  236. Wijnands M.V.W., Appel M.J., Hollanders V.M.H., Woutersen R.A., A comparison of the effects of dietary cellulose and fermentable galacto-oligosaccharide, in a rat model of colorectal carcinogenesis: fermentable fibre confers greater protection than non-fermentable fibre in both high and low fat backgrounds , 10.1093/carcin/20.4.651
  237. Femia A. P., Antitumorigenic activity of the prebiotic inulin enriched with oligofructose in combination with the probiotics Lactobacillus rhamnosus and Bifidobacterium lactis on azoxymethane-induced colon carcinogenesis in rats, 10.1093/carcin/23.11.1953
  238. Pierre, Cancer Res, 57, 225 (1997)
  239. Mutanen Marja, Pajari Anne-Maria, Oikarinen Seija I., Beef induces and rye bran prevents the formation of intestinal polyps in ApcMin mice: relation to β-catenin and PKC isozymes , 10.1093/carcin/21.6.1167
  240. Pajari Anne-Maria, Rajakangas Johanna, Päivärinta Essi, Kosma Veli-Matti, Rafter Joseph, Mutanen Marja, Promotion of intestinal tumor formation by inulin is associated with an accumulation of cytosolic β-catenin in Min mice : Inulin Promotes Intestinal Tumorigenesis in Min Mice, 10.1002/ijc.11270
  241. Pool-Zobel Beatrice L., Inulin-type fructans and reduction in colon cancer risk: review of experimental and human data, 10.1079/bjn20041349
  242. Taper, J Nutr, 129, 1488S (1999)
  243. Taper, In vivo, 19, 201 (2005)
  244. Gill C. I. R., Rowland I. R., Diet and cancer: assessing the risk, 10.1079/bjn2002632
  245. Rafter, Am J Clin Nutr, 85, 488 (2007)
  246. Rowland Ian R., Bearne Carol A., Fischer Roland, Pool‐Zobel Beatrice L., The effect of lactulose on DNA damage induced by DMH in the colon of human flora‐associated rats, 10.1080/01635589609514461
  247. Klinder Annett, Forster Antje, Caderni Giovanna, Femia Angelo Pietro, Pool-Zobel Beatrice L., Fecal Water Genotoxicity Is Predictive of Tumor-Preventive Activities by Inulin-Like Oligofructoses, Probiotics (Lactobacillus rhamnosus and Bifidobacterium lactis), and Their Synbiotic Combination, 10.1207/s15327914nc4902_5
  248. Perrin P, Only fibres promoting a stable butyrate producing colonic ecosystem decrease the rate of aberrant crypt foci in rats, 10.1136/gut.48.1.53
  249. Hughes R., Stimulation of apoptosis by two prebiotic chicory fructans in the rat colon, 10.1093/carcin/22.1.43
  250. Commane Daniel M., Shortt Colette T., Silvi Stefania, Cresci Albert, Hughes Roisin M., Rowland Ian R., Effects of Fermentation Products of Pro- and Prebiotics on Trans-Epithelial Electrical Resistance in an In Vitro Model of the Colon, 10.1207/s15327914nc5101_14
  251. Roberfroid M., Dietary fiber, inulin, and oligofructose: A review comparing their physiological effects, 10.1080/10408399309527616
  252. Roberfroid, Br J Nutr, 80, S197 (1998)
  253. Remesy, Am J Physiol, 264, G855 (1993)
  254. Ohta, J Nutr, 125, 2417 (1995)
  255. Lopez H, Fructooligosaccharides enhance mineral apparent absorption and counteract the deleterious effects of phytic acid on mineral homeostasis in rats, 10.1016/s0955-2863(00)00109-1
  256. Lutz T, Scharrer E, Effect of short-chain fatty acids on calcium absorption by the rat colon, 10.1113/expphysiol.1991.sp003530
  257. A. Ohta, Y. Motohashi, K. Sakai, M., Dietary Fructooligosaccharides Increase Calcium Absorption and Levels of Mucosal Calbindin-D9k in the Large Intestine of Gastrectomized Rats, 10.1080/003655298750026769
  258. Takasaki Misao, Inaba Hiromi, Ohta Atsutane, Motohashi Yasuko, Sakai Kensuke, Morris Howard, Sakuma Keiko, Dietary Short-Chain Fructooligosaccharides Increase Calbindin-D9k Levels Only in the Large Intestine in Rats Independent of Dietary Calcium Deficiency or Serum 1,25 Dihydroxy Vitamin D Levels, 10.1024/0300-9831.70.5.206
  259. Raschka Ladislav, Daniel Hannelore, Mechanisms underlying the effects of inulin-type fructans on calcium absorption in the large intestine of rats, 10.1016/j.bone.2005.05.015
  260. Scholz-Ahrens Katharina E., Schrezenmeir J., Inulin, oligofructose and mineral metabolism — experimental data and mechanism, 10.1079/bjn/2002535
  261. Heijnen Astrid M. P., Brink Elizabeth J., Lemmens Arnoldina G., Beynen Anton C., Ileal pH and apparent absorption of magnesium in rats fed on diets containing either lactose or lactulose, 10.1079/bjn19930170
  262. Beynen A. C., Baas J. C., Hoekemeijer P. E., Kappert H. J., Bakker M. H., Koopman J. P., Lemmens A. G., Faecal bacterial profile, nitrogen excretion and mineral absorption in healthy dogs fed supplemental oligofructose, 10.1046/j.1439-0396.2002.00386.x
  263. Rayssiguier, Ann Rech Vet, 8, 105 (1977)
  264. Leonhard-Marek S, Gabel G, Martens H, Effects of short chain fatty acids and carbon dioxide on magnesium transport across sheep rumen epithelium, 10.1113/expphysiol.1998.sp004098
  265. Delzenne N., Aertssens J., Verplaetse H., Roccaro M., Roberfroid M., Effect of fermentable fructo-oligosaccharides on mineral, nitrogen and energy digestive balance in the rat, 10.1016/0024-3205(95)02133-4
  266. Yap K.W., Mohamed S., Yazid A.M., Maznah I., Meyer D.M., Dose‐response effects of inulin on the faecal short‐chain fatty acids content and mineral absorption of formula‐fed infants, 10.1108/00346650510605603
  267. van den Heuvel, Am J Clin Nutr, 69, 544 (1999)
  268. Griffin I. J., Davila P. M., Abrams S. A., Non-digestible oligosaccharides and calcium absorption in girls with adequate calcium intakes, 10.1079/bjn/2002536
  269. Griffin Ian J, Hicks Penni M.D, Heaney Robert P, Abrams Steven A, Enriched chicory inulin increases calcium absorption mainly in girls with lower calcium absorption, 10.1016/s0271-5317(03)00085-x
  270. van den Heuvel Ellen G.H.M., Muijs Theo, Brouns Fred, Hendriks Henk F.J., Short-chain fructo-oligosaccharides improve magnesium absorption in adolescent girls with a low calcium intake, 10.1016/j.nutres.2009.03.005
  271. Abrams, Am J Clin Nutr, 82, 471 (2005)
  272. Cashman Kevin D., A Prebiotic Substance Persistently Enhances Intestinal Calcium Absorption and Increases Bone Mineralization in Young Adolescents, 10.1111/j.1753-4887.2006.tb00201.x
  273. Abrams, J Nutr, 137, 2524S (2007)
  274. Coudray C, Bellanger J, Castiglia-Delavaud C, Rémésy C, Vermorel M, Rayssignuier Y, Effect of soluble or partly soluble dietary fibres supplementation on absorption and balance of calcium, magnesium, iron and zinc in healthy young men, 10.1038/sj.ejcn.1600417
  275. van den Heuvel, Am J Clin Nutr, 67, 445 (1998)
  276. Teuri Ulla, Kärkkäinen Merja, Lamberg-Allardt Christel, Korpela Riitta, Addition of Inulin to Breakfast Does Not Acutely Affect Serum Ionized Calcium and Parathyroid Hormone Concentrations, 10.1159/000012804
  277. Lopez-Huertas, Am J Clin Nutr, 83, 310 (2006)
  278. Abrams, J Nutr, 137, 2208 (2007)
  279. Ducros Véronique, Arnaud Josiane, Tahiri Maha, Coudray Charles, Bornet Francis, Bouteloup-Demange Corinne, Brouns Fred, Rayssiguier Yves, Roussel Anne Marie, Influence of Short-Chain Fructo-Oligosaccharides (sc-FOS) on Absorption of Cu, Zn, and Se in Healthy Postmenopausal Women, 10.1080/07315724.2005.10719440
  280. Tahiri Maha, Tressol Jean C., Arnaud Josiane, Bornet Francis, Bouteloup-Demange Corinne, Feillet-Coudray Christine, Ducros Véronique, Pépin Denise, Brouns Fred, Roussel Anne M., Rayssiguier Yves, Coudray Charles, Five-Week Intake of Short-Chain Fructo-Oligosaccharides Increases Intestinal Absorption and Status of Magnesium in Postmenopausal Women, 10.1359/jbmr.2001.16.11.2152
  281. Tahiri, Am J Clin Nutr, 77, 449 (2003)
  282. van den heuvel Ellen G. H. M., Muijs Theo, van dokkum Wim, Schaafsma Gertjan, Lactulose Stimulates Calcium Absorption in Postmenopausal Women, 10.1359/jbmr.1999.14.7.1211
  283. van den Heuvel, J Nutr, 130, 2938 (2000)
  284. Adolphi Berit, Scholz-Ahrens Katharina E., de Vrese Michael, Açil Yahya, Laue Christiane, Schrezenmeir Jürgen, Short-term effect of bedtime consumption of fermented milk supplemented with calcium, inulin-type fructans and caseinphosphopeptides on bone metabolism in healthy, postmenopausal women, 10.1007/s00394-008-0759-y
  285. Kim, Nutr Sci, 7, 151 (2004)
  286. Holloway Leah, Moynihan Sharon, Abrams Steven A., Kent Kyla, Hsu Andrew R., Friedlander Anne L., Effects of oligofructose-enriched inulin on intestinal absorption of calcium and magnesium and bone turnover markers in postmenopausal women, 10.1017/s000711450733674x
  287. Dahl Wendy J., Whiting Susan J., Isaac Teresa M., Weeks Shawna J., Arnold Chris J., Effects of thickened beverages fortified with inulin on beverage acceptance, gastrointestinal function, and bone resorption in institutionalized adults, 10.1016/j.nut.2004.06.025
  288. Levrat, J Nutr, 121, 1730 (1991)
  289. Ohta, Int J Vitam Nutr Res, 64, 316 (1994)
  290. Ellegård L, Andersson H, Bosaeus I, Inulin and oligofructose do not influence the absorption of cholesterol, or the excretion of cholesterol, Ca, Mg, Zn, Fe, or bile acids but increases energy excretion in ileostomy subjects, 10.1038/sj.ejcn.1600320
  291. Scholz-Ahrens, Am J Clin Nutr, 73, 459S (2001)
  292. Brommage, J Nutr, 123, 2186 (1993)
  293. Scholz-Ahrens Katharina E., Açil Yahya, Schrezenmeir Jürgen, Effect of oligofructose or dietary calcium on repeated calcium and phosphorus balances, bone mineralization and trabecular structure in ovariectomized rats, 10.1079/bjn2002661
  294. Kruger, Exp Biol Med (Maywood), 228, 683 (2003)
  295. Coudray Charles, Tressol Jean Claude, Gueux Elyett, Rayssiguier Yves, Effects of inulin-type fructans of different chain length and type of branching on intestinal absorption and balance of calcium and magnesium in rats, 10.1007/s00394-003-0390-x
  296. Coxam Véronique, Inulin-type fructans and bone health: state of the art and perspectives in the management of osteoporosis, 10.1079/bjn20041341
  297. Setchell, J Nutr, 132, 3577 (2002)
  298. Uehara, J Nutr, 131, 787 (2001)
  299. Ohta, J Nutr, 132, 2048 (2002)
  300. Mathey J., Puel C., Kati-Coulibaly S., Bennetau–Pelissero C., Davicco M. J., Lebecque P., Horcajada M. N., Coxam V., Fructooligosaccharides Maximize Bone-Sparing Effects of Soy Isoflavone-Enriched Diet in the Ovariectomized Rat, 10.1007/s00223-004-0128-7
  301. Devareddy Latha, Khalil Dania A., Korlagunta Kiranmayi, Hooshmand Shirin, Bellmer Danielle D., Arjmandi Bahram H., The effects of fructo-oligosaccharides in combination with soy protein on bone in osteopenic ovariectomized rats : , 10.1097/01.gme.0000195372.74944.71
  302. Zafar Tasleem A., Weaver Connie M., Jones Kenneth, Moore D. Ray, Barnes Stephen, Inulin Effects on Bioavailability of Soy Isoflavones and Their Calcium Absorption Enhancing Ability, 10.1021/jf035080f
  303. Piazza, Am J Clin Nutr, 86, 775 (2007)
  304. OHTA Atsutane, BABA Seigo, TAKIZAWA Toshio, ADACHI Takashi, Effects of Fructooligosaccharides on the Absorption of Magnesium in the Magnesium-Deficient Rat Model., 10.3177/jnsv.40.171
  305. OHTA Atsutane, OHTSUKI Masako, BABA Seigo, TAKIZAWA Toshio, ADACHI Takashi, KIMURA Shuichi, Effects of Fructooligosaccharides on the Absorption of Iron, Calcium and Magnesium in Iron-deficient Anemic Rats., 10.3177/jnsv.41.281
  306. Kobayashi, Int J Mol Med, 18, 1159 (2006)
  307. Cani Patrice, Delzenne Nathalie, The Role of the Gut Microbiota in Energy Metabolism and Metabolic Disease, 10.2174/138161209788168164
  308. Daubioul, J Nutr, 132, 967 (2002)
  309. Cani P. D., Possemiers S., Van de Wiele T., Guiot Y., Everard A., Rottier O., Geurts L., Naslain D., Neyrinck A., Lambert D. M., Muccioli G. G., Delzenne N. M., Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability, 10.1136/gut.2008.165886
  310. Chaudhri Owais B., Salem Victoria, Murphy Kevin G., Bloom Stephen R., Gastrointestinal Satiety Signals, 10.1146/annurev.physiol.70.113006.100506
  311. Druce Maralyn R., Small Caroline J., Bloom Stephen R., Minireview: Gut Peptides Regulating Satiety, 10.1210/en.2004-0089
  312. Wynne K., Appetite control, 10.1677/joe.1.05866
  313. Knauf C., Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage, 10.1172/jci25764
  314. Cani Patrice D., Dewever Cédric, Delzenne Nathalie M., Inulin-type fructans modulate gastrointestinal peptides involved in appetite regulation (glucagon-like peptide-1 and ghrelin) in rats, 10.1079/bjn20041225
  315. Delzenne Nathalie M., Cani Patrice D., Daubioul Catherine, Neyrinck Audrey M., Impact of inulin and oligofructose on gastrointestinal peptides, 10.1079/bjn20041342
  316. Urías-Silvas Judith E., Cani Patrice D., Delmée Evelyne, Neyrinck Audrey, López Mercedes G., Delzenne Nathalie M., Physiological effects of dietary fructans extracted from Agave tequilana Gto. and Dasylirion spp., 10.1017/s0007114507795338
  317. Cani P. D., Knauf C., Iglesias M. A., Drucker D. J., Delzenne N. M., Burcelin R., Improvement of Glucose Tolerance and Hepatic Insulin Sensitivity by Oligofructose Requires a Functional Glucagon-Like Peptide 1 Receptor, 10.2337/db05-1360
  318. Reimer Raylene A, Russell James C, Glucose Tolerance, Lipids, and GLP-1 Secretion in JCR:LA-cp Rats Fed a High Protein Fiber Diet, 10.1038/oby.2007.16
  319. Maurer Alannah D., Chen Qixuan, McPherson Christine, Reimer Raylene A., Changes in satiety hormones and expression of genes involved in glucose and lipid metabolism in rats weaned onto diets high in fibre or protein reflect susceptibility to increased fat mass in adulthood : Early high fibre or protein diets, 10.1113/jphysiol.2008.161844
  320. Cani Patrice D., Hoste Sophie, Guiot Yves, Delzenne Nathalie M., Dietary non-digestible carbohydrates promote L-cell differentiation in the proximal colon of rats, 10.1017/s0007114507691648
  321. Cani P D, Joly E, Horsmans Y, Delzenne N M, Oligofructose promotes satiety in healthy human: a pilot study, 10.1038/sj.ejcn.1602350
  322. Archer Bridie J., Johnson Stuart K., Devereux Helen M., Baxter Amynta L., Effect of fat replacement by inulin or lupin-kernel fibre on sausage patty acceptability, post-meal perceptions of satiety and food intake in men, 10.1079/bjn20031088
  323. Piche Thierry, des Varannes Stanislas Bruley, Sacher-Huvelin Sylvie, Holst Jens Juul, Cuber Jean Claude, Galmiche Jean Paul, Colonic fermentation influences lower esophageal sphincter function in gastroesophageal reflux disease, 10.1053/gast.2003.50159
  324. Cani P. D, Lecourt E., Dewulf E. M, Sohet F. M, Pachikian B. D, Naslain D., De Backer F., Neyrinck A. M, Delzenne N. M, Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal, 10.3945/ajcn.2009.28095
  325. Abrams Steven A., Griffin Ian J., Hawthorne Keli M., Ellis Kenneth J., Effect of Prebiotic Supplementation and Calcium Intake on Body Mass Index, 10.1016/j.jpeds.2007.03.043
  326. Genta Susana, Cabrera Wilfredo, Habib Natalia, Pons Juan, Carillo Iván Manrique, Grau Alfredo, Sánchez Sara, Yacon syrup: Beneficial effects on obesity and insulin resistance in humans, 10.1016/j.clnu.2009.01.013
  327. Parnell J. A, Reimer R. A, Weight loss during oligofructose supplementation is associated with decreased ghrelin and increased peptide YY in overweight and obese adults, 10.3945/ajcn.2009.27465
  328. Peters H. P., Boers H. M, Haddeman E., Melnikov S. M, Qvyjt F., No effect of added  -glucan or of fructooligosaccharide on appetite or energy intake, 10.3945/ajcn.2008.26701
  329. Busserolles, J Nutr, 133, 1903 (2003)
  330. Cani Patrice D., Neyrinck Audrey M., Maton Nicole, Delzenne Nathalie M., Oligofructose Promotes Satiety in Rats Fed a High-Fat Diet: Involvement of Glucagon-Like Peptide-1, 10.1038/oby.2005.117
  331. Delmée Evelyne, Cani Patrice D., Gual Gisèle, Knauf Claude, Burcelin Rémy, Maton Nicole, Delzenne Nathalie M., Relation between colonic proglucagon expression and metabolic response to oligofructose in high fat diet-fed mice, 10.1016/j.lfs.2006.05.013
  332. Cani P. D, Involvement of endogenous glucagon-like peptide-1(7-36) amide on glycaemia-lowering effect of oligofructose in streptozotocin-treated rats, 10.1677/joe.1.06100
  333. Perrin, Diab Nutr Metabol, 16, 94 (2003)
  334. Respondek, J Nutr, 138, 1712 (2008)
  335. Luo, Am J Clin Nutr, 63, 939 (1996)
  336. Luo, J Nutr, 130, 1572 (2000)
  337. Giacco R, Clemente G, Luongo D, Lasorella G, Fiume I, Brouns F, Bornet F, Patti L, Cipriano P, Rivellese A.A, Riccardi G, Effects of short-chain fructo-oligosaccharides on glucose and lipid metabolism in mild hypercholesterolaemic individuals, 10.1016/j.clnu.2003.07.010
  338. Delzenne Nathalie M., Cani Patrice D., Implication de la flore intestinale dans le métabolisme énergétique, 10.1051/medsci/2008245505
  339. Delzenne Nathalie M., Williams Christine M., Prebiotics and lipid metabolism : , 10.1097/00041433-200202000-00009
  340. Daubioul, J Nutr, 130, 1314 (2000)
  341. Morand, Am J Physiol, 264, E816 (1993)
  342. Delzenne N. M., Daubioul C., Neyrinck A., Lasa M., Taper H. S., Inulin and oligofructose modulate lipid metabolism in animals: review of biochemical events and future prospects, 10.1079/bjn/2002545
  343. Sakakibara Shoji, Yamauchi Toshimasa, Oshima Yoshifumi, Tsukamoto Yoshinori, Kadowaki Takashi, Acetic acid activates hepatic AMPK and reduces hyperglycemia in diabetic KK-A(y) mice, 10.1016/j.bbrc.2006.03.176
  344. Levrat, J Nutr, 124, 531 (1994)
  345. Fiordaliso Maria, Kok Nadine, Desager Jean-Pierre, Goethals Fabienne, Deboyser Dominique, Roberfroid Marcel, Delzenne Nathalie, Dietary oligofructose lowers triglycerides, phospholipids and cholesterol in serum and very low density lipoproteins of rats, 10.1007/bf02538270
  346. Rault-Nania Marie-Hélène, Gueux Elyett, Demougeot Céline, Demigné Christian, Rock Edmond, Mazur Andrzej, Inulin attenuates atherosclerosis in apolipoprotein E-deficient mice, 10.1017/bjn20061913
  347. Bentham Science Publisher Bentham Science Publisher, The Gut Microbiota and Lipid Metabolism: Implications for Human Health and Coronary Heart Disease, 10.2174/092986706778521814
  348. Trautwein Elke A, Forgbert Karin, Rieckhoff Dörte, Erbersdobler Helmut F, Impact of β-cyclodextrin and resistant starch on bile acid metabolism and fecal steroid excretion in regard to their hypolipidemic action in hamsters1Presented in part at Experimental Biology 98, 18–22 April, 1998, San Francisco, CA, USA.1, 10.1016/s0005-2760(98)00174-x
  349. Adam, J Nutr, 131, 1770 (2001)
  350. van Meer H., Boehm G., Stellaard F., Vriesema A., Knol J., Havinga R., Sauer P. J., Verkade H. J., Prebiotic oligosaccharides and the enterohepatic circulation of bile salts in rats, 10.1152/ajpgi.00396.2007
  351. Brighenti, J Nutr, 137, 2552S (2007)
  352. Diraison F, Moulin Ph, Beylot M, Contribution of hepatic de novo lipogenesis and reesterification of plasma non esterified fatty acids to plasma triglyceride synthesis during non-alcoholic fatty liver disease, 10.1016/s1262-3636(07)70061-7
  353. Daubioul C A, Horsmans Y, Lambert P, Danse E, Delzenne N M, Effects of oligofructose on glucose and lipid metabolism in patients with nonalcoholic steatohepatitis: results of a pilot study, 10.1038/sj.ejcn.1602127
  354. Cani Patrice D, Delzenne Nathalie M, Interplay between obesity and associated metabolic disorders: new insights into the gut microbiota, 10.1016/j.coph.2009.06.016
  355. Cani P. D., Amar J., Iglesias M. A., Poggi M., Knauf C., Bastelica D., Neyrinck A. M., Fava F., Tuohy K. M., Chabo C., Waget A., Delmee E., Cousin B., Sulpice T., Chamontin B., Ferrieres J., Tanti J.-F., Gibson G. R., Casteilla L., Delzenne N. M., Alessi M. C., Burcelin R., Metabolic Endotoxemia Initiates Obesity and Insulin Resistance, 10.2337/db06-1491
  356. Turnbaugh Peter J., Bäckhed Fredrik, Fulton Lucinda, Gordon Jeffrey I., Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome, 10.1016/j.chom.2008.02.015
  357. Cani P. D., Neyrinck A. M., Fava F., Knauf C., Burcelin R. G., Tuohy K. M., Gibson G. R., Delzenne N. M., Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia, 10.1007/s00125-007-0791-0
  358. Cani P. D., Bibiloni R., Knauf C., Waget A., Neyrinck A. M., Delzenne N. M., Burcelin R., Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet-Induced Obesity and Diabetes in Mice, 10.2337/db07-1403
  359. Waldram Alison, Holmes Elaine, Wang Yulan, Rantalainen Mattias, Wilson Ian D., Tuohy Kieran M., McCartney Anne L., Gibson Glenn R., Nicholson Jeremy K., Top-Down Systems Biology Modeling of Host Metabotype−Microbiome Associations in Obese Rodents, 10.1021/pr8009885
  360. Wang Zhongtang, Xiao Guangxia, Yao Yongming, Guo Shuzhong, Lu Kaihua, Sheng Zhiyong, The Role of Bifidobacteria in Gut Barrier Function After Thermal Injury in Rats : , 10.1097/01.ta.0000196574.70614.27
  361. Griffiths Elizabeth A., Duffy Linda C., Schanbacher Floyd L., Qiao Haiping, Dryja Diane, Leavens Allen, Rossman Jon, Rich Gary, Dirienzo Douglas, Ogra Pearay L., In Vivo Effects of Bifidobacteria and Lactoferrin on Gut Endotoxin Concentration and Mucosal Immunity in Balb/c Mice, 10.1023/
  362. Wang Zhong-Tang, Risk factors of development of gut-derived bacterial translocation in thermally injured rats, 10.3748/wjg.v10.i11.1619
  363. Ruan Xiangcai, Shi Hanping, Xia Gengfeng, Xiao Ying, Dong Jiaxi, Ming Feiping, Wang Shenming, Encapsulated Bifidobacteria reduced bacterial translocation in rats following hemorrhagic shock and resuscitation, 10.1016/j.nut.2007.07.002
  364. Keenan Michael J., Zhou Jun, McCutcheon Kathleen L., Raggio Anne M., Bateman H. Gale, Todd Emily, Jones Christina K., Tulley Richard T., Melton Sheri, Martin Roy J., Hegsted Maren, Effects of Resistant Starch, A Non-digestible Fermentable Fiber, on Reducing Body Fat*, 10.1038/oby.2006.176
  365. Zhou J., Martin R. J., Tulley R. T., Raggio A. M., McCutcheon K. L., Shen L., Danna S. C., Tripathy S., Hegsted M., Keenan M. J., Dietary resistant starch upregulates total GLP-1 and PYY in a sustained day-long manner through fermentation in rodents, 10.1152/ajpendo.90637.2008
  366. Juntunen, Am J Clin Nutr, 75, 254 (2002)
  367. Adam T. C., Westerterp-Plantenga M. S., Nutrient-stimulated GLP-1 Release in Normal-weight Men and Women, 10.1055/s-2005-861160
  368. Nilsson, J Nutr, 138, 732 (2008)
  369. Gao Z., Yin J., Zhang J., Ward R. E., Martin R. J., Lefevre M., Cefalu W. T., Ye J., Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice, 10.2337/db08-1637
  370. Kalliomaki, Am J Clin Nutr, 87, 534 (2008)
  371. Lundell A-C., Adlerberth I., Lindberg E., Karlsson H., Ekberg S., Åberg N., Saalman R., Hock B., Steinkasserer A., Hesselmar B., Wold A. E., Rudin A., Increased levels of circulating soluble CD14 but not CD83 in infants are associated with early intestinal colonization with Staphylococcus aureus, 10.1111/j.1365-2222.2006.02625.x
  372. Grönlund M.-M., Gueimonde M., Laitinen K., Kociubinski G., Grönroos T., Salminen S., Isolauri E., Maternal breast-milk and intestinal bifidobacteria guide the compositional development of the Bifidobacterium microbiota in infants at risk of allergic disease, 10.1111/j.1365-2222.2007.02849.x
  373. Salminen S., Bouley C., Boutron M.-C., Cummings J. H., Franck A., Gibson G. R., Isolauri E., Moreau M.-C., Roberfroid M., Rowland I., Functional food science and gastrointestinal physiology and function, 10.1079/bjn19980108
  374. Salminen S, Influence of mode of delivery on gut microbiota composition in seven year old children, 10.1136/gut.2004.041640
  375. Salminen Seppo, Isolauri Erika, Opportunities for Improving the Health and Nutrition of the Human Infant by Probiotics, Nestlé Nutrition Workshop Series: Pediatric Program (2008) ISBN:9783805585538 p.223-237, 10.1159/000146350
  376. Salminen Seppo, Collado Maria Carmen, Isolauri Erika, Gueimonde Miguel, Microbial–Host Interactions: Selecting the Right Probiotics and Prebiotics for Infants, Microbial Host-Interaction: Tolerance versus Allergy (2009) ISBN:9783805591676 p.201-217, 10.1159/000235792
  377. Bellisle F., Blundell J. E., Dye L., Fantino M., Fern E., Fletcher R. J., Lambed J., Roberfroid M., Specter S., Westenhöfer J., Westerterp-Plantenga M. S., Functional food science and behaviour and psychological functions, 10.1079/bjn19980109
  378. Walter J., Tannock G. W., Tilsala-Timisjarvi A., Rodtong S., Loach D. M., Munro K., Alatossava T., Detection and Identification of Gastrointestinal Lactobacillus Species by Using Denaturing Gradient Gel Electrophoresis and Species-Specific PCR Primers, 10.1128/aem.66.1.297-303.2000
  379. Satokari R. M., Vaughan E. E., Akkermans A. D. L., Saarela M., de Vos W. M., Bifidobacterial Diversity in Human Feces Detected by Genus-Specific PCR and Denaturing Gradient Gel Electrophoresis, 10.1128/aem.67.2.504-513.2001
  380. Heilig H. G.H.J., Zoetendal E. G., Vaughan E. E., Marteau P., Akkermans A. D.L., de Vos W. M., Molecular Diversity of Lactobacillus spp. and Other Lactic Acid Bacteria in the Human Intestine as Determined by Specific Amplification of 16S Ribosomal DNA, 10.1128/aem.68.1.114-123.2002
  381. Shen J., Zhang B., Wei G., Pang X., Wei H., Li M., Zhang Y., Jia W., Zhao L., Molecular Profiling of the Clostridium leptum Subgroup in Human Fecal Microflora by PCR-Denaturing Gradient Gel Electrophoresis and Clone Library Analysis, 10.1128/aem.00151-06
  382. Vanhoutte T., De Preter V., De Brandt E., Verbeke K., Swings J., Huys G., Molecular Monitoring of the Fecal Microbiota of Healthy Human Subjects during Administration of Lactulose and Saccharomyces boulardii, 10.1128/aem.00233-06
  383. Kruse, Br J Nutr, 82, 375 (1999)
  384. Bouhnik, J Nutr, 129, 113 (1999)
  385. Gibson Glenn R., Beatty Emily R., Wang Xin, Cummings John H., Selective stimulation of bifidobacteria in the human colon by oligofructose and inulin, 10.1016/0016-5085(95)90192-2
  386. Kleessen, Am J Clin Nutr, 65, 1397 (1997)
  387. Tuohy K. M., Kolida S., Lustenberger A. M., Gibson G. R., The prebiotic effects of biscuits containing partially hydrolysed guar gum and fructo-oligosaccharides – a human volunteer study, 10.1079/bjn2001394
  388. Buddington, Am J Clin Nutr, 63, 709 (1996)
  389. Menne, J Nutr, 130, 1197 (2000)
  390. TEURI Ulla, KORPELA Riitta, SAXELIN Maijta, MONTONEN Leone, SALMINEN Seppo, Increased Fecal Frequency and Gastrointestinal Symptoms Following Ingestion of Galacto-Oligosaccharide-Containing Yogurt., 10.3177/jnsv.44.465
  391. Moro G., Minoli I., Mosca M., Fanaro S., Jelinek J., Stahl B., Boehm G., Dosage-Related Bifidogenic Effects of Galacto- and Fructooligosaccharides in Formula-Fed Term Infants : , 10.1097/00005176-200203000-00014
  392. Bouhnik, Am J Clin Nutr, 80, 1658 (2004)
  393. Bouhnik Yoram, Achour Lotfi, Paineau Damien, Riottot Michel, Attar Alain, Bornet Francis, Four-week short chain fructo-oligosaccharides ingestion leads to increasing fecal bifidobacteria and cholesterol excretion in healthy elderly volunteers, 10.1186/1475-2891-6-42
  394. Kleessen Brigitta, Schwarz Sandra, Boehm Anke, Fuhrmann H., Richter A., Henle T., Krueger Monika, Jerusalem artichoke and chicory inulin in bakery products affect faecal microbiota of healthy volunteers, 10.1017/s0007114507730751
  395. Tuohy Kieran M., Finlay Rochelle K., Wynne Anthony G., Gibson Glenn R., A Human Volunteer Study on the Prebiotic Effects of HP-Inulin—Faecal Bacteria Enumerated Using Fluorescent In Situ Hybridisation (FISH), 10.1006/anae.2001.0368
  396. Williams C. H., Witherly S. A., Buddington R. K., Influence of Dietary Neosugar on Selected Bacterial Groups of the Human Faecal Microbiota, 10.3109/08910609409141577
  397. Depeint, Am J Clin Nutr, 87, 785 (2008)
  398. Bakker-Zierikzee Astrid M., Alles Martine S., Knol Jan, Kok Frans J., Tolboom Jules J. M., Bindels Jacques G., Effects of infant formula containing a mixture of galacto- and fructo-oligosaccharides or viable Bifidobacterium animalis on the intestinal microflora during the first 4 months of life, 10.1079/bjn20051451
  399. Mättö Jaana, Maunuksela Liisa, Kajander Kajsa, Palva Airi, Korpela Riitta, Kassinen Anna, Saarela Maria, Composition and temporal stability of gastrointestinal microbiota in irritable bowel syndrome – a longitudinal study in IBS and control subjects, 10.1016/j.femsim.2004.08.009
  400. Walker, Int J Obes, 11, 45 (1987)
  401. Roberfroid, Dietary Fiber in Health and Disease (1997)
  402. Coudray, Am J Clin Nutr, 68, 921 (1998)
  403. Schaafsma, Eur J Clin Nutr, 51, S13 (1997)
  404. Fairweather-Tait Susan J., Johnson Ian T., Bioavailability of Minerals, Colonic Microbiota, Nutrition and Health (1999) ISBN:9789048140220 p.233-244, 10.1007/978-94-017-1079-4_14
  405. Carabin Ioana G., Flamm W.Gary, Evaluation of Safety of Inulin and Oligofructose as Dietary Fiber, 10.1006/rtph.1999.1349
  406. Franck, Functional Foods, 108 (2000)
  407. van Dokkum, Handbook of Dietary Fiber, 259 (2001)
  408. Roberfroid Marcel B., Functional foods: concepts and application to inulin and oligofructose, 10.1079/bjn/2002529
  409. Cashman K. D., Calcium intake, calcium bioavailability and bone health, 10.1079/bjn/2002534
  410. Kaur Narinder, Gupta Anil K., Applications of inulin and oligofructose in health and nutrition, 10.1007/bf02708379
  411. Cashman, Probiotics and Prebiotics: Where Are We going?, 149 (2002)
  412. Bongers Anke, van den Heuvel Ellen G. H. M., Prebiotics and the Bioavailability of Minerals and Trace Elements, 10.1081/fri-120025482
  413. Cashman, Curr Issues Intest Microbiol, 4, 21 (2003)
  414. Caers, Dietary Fibre Congress – Conference Proceedings, 46 (2003)
  415. Coudray, J Nutr, 133, 1 (2003)
  416. Coudray, Agro Food Industry Hi-Tech, 15, 40 (2004)
  417. Weaver Connie M., Inulin, oligofructose and bone health: experimental approaches and mechanisms, 10.1079/bjn20041358
  418. Franck A., Oligofructose-enriched inulin stimulates calcium absorption and bone mineralisation, 10.1111/j.1467-3010.2006.00584.x
  419. Bosscher D., Van Loo J., Franck A., Inulin and oligofructose as functional ingredients to improve bone mineralization, 10.1016/j.idairyj.2005.10.028
  420. Coxam, J Nutr, 137, 2527S (2007)
  421. Scholz-Ahrens, J Nutr, 137, 2513S (2007)
  422. Scholz-Ahrens, J Nutr, 137, 838S (2007)
  423. Alexiou H., Franck A., Prebiotic inulin-type fructans: nutritional benefits beyond dietary fibre source, 10.1111/j.1467-3010.2008.00710.x
  424. Gibson Glenn R., Delzenne Nathalie, Inulin and Oligofructose : New Scientific Developments, 10.1097/01.nt.0000303311.36663.39
  425. de Vrese, Adv Biochem Eng Biotechnol, 111, 1 (2008)
  426. Griffin, Handbook of Prebiotics, 93 (2007)
  427. Hawthorne, Handbook of Prebiotics, 105 (2007)
  428. Kelly, Altern Med Rev, 14, 36 (2009)
  429. de Vrese M., Health benefits of probiotics and prebiotics in women, 10.1258/mi.2009.009008
  430. Chonan Osamu, Matsumoto Keisuke, Watanuki Masaaki, Effect of Galactooligosaccharides on Calcium Absorption and Preventing Bone Loss in Ovariectomized Rats, 10.1271/bbb.59.236
  431. Takahara, J Nutr, 130, 1792 (2000)
  432. Richardson, IFT USA (2002)
  433. Zafar, J Nutr, 134, 399 (2004)
  434. Mitamura Rieko, Hara Hiroshi, Prolonged feeding of difructose anhydride III increases strength and mineral concentrations of the femur in ovariectomized rats, 10.1079/bjn20051483
  435. Mitamura Rieko, Hara Hiroshi, Ingestion of difructose anhydride III partially restores calcium absorption impaired by vitamin D and estrogen deficiency in rats, 10.1007/s00394-006-0592-0
  436. Nzeusseu Adrien, Dienst Dominique, Haufroid Vincent, Depresseux Geneviève, Devogelaer Jean-Pierre, Manicourt Daniel-Henri, Inulin and fructo-oligosaccharides differ in their ability to enhance the density of cancellous and cortical bone in the axial and peripheral skeleton of growing rats, 10.1016/j.bone.2005.09.006
  437. Lobo Alexandre R., Colli Célia, Filisetti Tullia M.C.C., Fructooligosaccharides improve bone mass and biomechanical properties in rats, 10.1016/j.nutres.2006.06.019
  438. Jamieson Jennifer A., Ryz Natasha R., Taylor Carla G., Weiler Hope A., Dietary long-chain inulin reduces abdominal fat but has no effect on bone density in growing female rats, 10.1017/s0007114508894378
  439. Demigné Christian, Jacobs Heidi, Moundras Corinne, Davicco Marie-Jeanne, Horcajada Marie-Noëlle, Bernalier Annick, Coxam Véronique, Comparison of native or reformulated chicory fructans, or non-purified chicory, on rat cecal fermentation and mineral metabolism, 10.1007/s00394-008-0736-5
  440. Lobo Alexandre Rodrigues, Filho Jorge Mancini, Alvares Eliana Parisi, Cocato Maria Lucia, Colli Célia, Effects of dietary lipid composition and inulin-type fructans on mineral bioavailability in growing rats, 10.1016/j.nut.2008.08.002
  441. Rondon, Magnes Res, 21, 224 (2008)
  442. CHONAN Osamu, WATANUKI Masaaki, Effect of Galactooligosaccharides on Calcium Absorption in Rats., 10.3177/jnsv.41.95
  443. YANAHIRA Shuichi, MORITA Minoru, AOE Seiichiro, SUGURI Toshiaki, TAKADA Yukihiro, MIURA Susumu, NAKAJIMA Ichiro, Effects of Lactitol-Oligosaccharides on Calcium and Magnesium Absorption in Rats., 10.3177/jnsv.43.123
  444. Morohashi, J Nutr, 128, 1815 (1998)
  445. Younes Hassan, Coudray Charles, Bellanger Jacques, Demigné Christian, Rayssiguier Yves, Rémésy Christian, Effects of two fermentable carbohydrates (inulin and resistant starch) and their combination on calcium and magnesium balance in rats, 10.1079/bjn2001430
  446. Mitamura, J Nutr, 132, 3387 (2002)
  447. Asvarujanon Patchana, Ishizuka Satoshi, Hara Hiroshi, Promotive effects of non-digestible disaccharides on rat mineral absorption depend on the type of saccharide, 10.1016/j.nut.2005.02.011
  448. Coudray C., Feillet-Coudray C., Tressol J. C., Gueux E., Thien S., Jaffrelo L., Mazur A., Rayssiguier Y., Stimulatory effect of inulin on intestinal absorption of calcium and magnesium in rats is modulated by dietary calcium intakes : Short– and long–term balance studies, 10.1007/s00394-004-0526-7
  449. Coudray Charles, Rambeau Mathieu, Feillet-Coudray Christine, Tressol Jean Claude, Demigne Christian, Gueux Elyett, Mazur Andrzej, Rayssiguier Yves, Dietary inulin intake and age can significantly affect intestinal absorption of calcium and magnesium in rats: a stable isotope approach, 10.1186/1475-2891-4-29
  450. Shiga Kazuki, Nishimukai Megumi, Tomita Fusao, Hara Hiroshi, Ingestion of difructose anhydride III, a non-digestible disaccharide, prevents gastrectomy-induced iron malabsorption and anemia in rats, 10.1016/j.nut.2005.12.013
  451. Coudray, J Nutr, 136, 117 (2006)
  452. Azorín-Ortuño María, Urbán Cristina, Cerón José J., Tecles Fernando, Allende Ana, Tomás-Barberán Francisco A., Espín Juan Carlos, Effect of low inulin doses with different polymerisation degree on lipid metabolism, mineral absorption, and intestinal microbiota in rats with fat-supplemented diet, 10.1016/j.foodchem.2008.08.062
  453. Klobukowsk Jan, Modzelewsk Monika, Kornacki Kazimierz, Calcium Bioavailability from Diets Based on White Cheese Containing Probiotics or Synbiotics in Short-Time Study in Rats, 10.3923/pjn.2009.933.936
  454. Wang Yu, Zeng Tao, Wang Shu-e, Wang Wei, Wang Qian, Yu Hong-Xia, Fructo-oligosaccharides enhance the mineral absorption and counteract the adverse effects of phytic acid in mice, 10.1016/j.nut.2009.04.014
  455. Mathey, Clinl Med Women's Health, 1, 15 (2008)
  456. Sakaguchi, Br J Nutr, 80, 469 (1998)
  457. Juskiewicz J., Jankowski J., Zdunczyk Z., Mikulski D., Performance and Gastrointestinal Tract Metabolism of Turkeys Fed Diets with Different Contents of Fructooligosaccharides, 10.1093/ps/85.5.886
  458. Zduńczyk Zenon, Juśkiewicz Jerzy, Estrella Isabel, Cecal parameters of rats fed diets containing grapefruit polyphenols and inulin as single supplements or in a combination, 10.1016/j.nut.2006.05.010
  459. Sugatani J., Dietary Inulin Alleviates Hepatic Steatosis and Xenobiotics-Induced Liver Injury in Rats Fed a High-Fat and High-Sucrose Diet: Association with the Suppression of Hepatic Cytochrome P450 and Hepatocyte Nuclear Factor 4  Expression, 10.1124/dmd.106.010645
Référence bibliographique Roberfroid, Marcel ; Gibson, Glenn R. ; Hoyles, Lesley ; McCartney, Anne L. ; Rastall, Robert ; et. al. Prebiotic effects: metabolic and health benefits.. In: The British Journal of Nutrition : an international journal of nutritional science, Vol. 104, no. Suppl 2, p. S1-S63 (2010)