A new fast non rigid registration algorithm is presented. The algorithm estimates a dense deformation field by optimizing a criterion that measures image similarity by mutual information and regularizes with a linear elastic energy term. The optimal deformation field is found using a Simultaneous Perturbation Stochastic Approximation to the gradient. The implementation is parallelized for symmetric multi-processor architectures. This algorithm was applied to capture non-rigid brain deformations that occur during neurosurgery. Segmentation of the intra-operative data is not required but preoperative segmentation of the brain allows the algorithm to be robust to artifacts due to the craniotomy.
De Craene, M.S. ; Du Bois d'Aische, Aloys ; Talos, I.-F. ; Ferrant, M. ; Black, P.M. ; et. al. Dense deformation field estimation for brain intraoperative images registration.Medical Imaging 2004. Image Processing (San Diego, CA, USA, 16-19 February 2004). In: SPIE - the International Society for Optical Engineering. Proceedings, Spie-int. soc. opt. eng2004, p.Vol. 5370, p. 1216-1224