NetPath: a public resource of curated signal transduction pathways

Kandasamy, Kumaran Mohan, Sujatha [International Tech Park, Bangalore 560066, India] Raju, Rajesh [International Tech Park, Bangalore 560066, India] Keeerthikumar, Shivakumar [International Tech Park, Bangalore 560066, India] Zhong, Jun [Johns Hopkins University, Baltimore, Maryland 21205, USA.] Ramachandra, YL [Kuvempu University, Jnanasahyadri, Shimoga 577451, India] Desiderio, Stephen [Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA] Houtman, Jon CD [University of Iowa, Iowa City, Iowa 52242, USA] Bader, Gary D [Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA] Draghici, Sorin [Wayne State University, Detroit, Michigan 48202, USA] Khatri, Purvesh [Wayne State University, Detroit, Michigan 48202, USA] Pecquet, Christian [UCL] Sameer Kumar, Ghantasala S [International Tech Park, Bangalore 560066, India] Venugopal, Abhilash K [International Tech Park, Bangalore 560066, India] Teilikicherla, Deepthi [International Tech Park, Bangalore 560066, India] Navarro, J Daniel [International Tech Park, Bangalore 560066, India] Mathivanan, Suresh [International Tech Park, Bangalore 560066, India] Gollapudi, Sashi Kanth [International Tech Park, Bangalore 560066, India] Tattikota, Sudhir Gopal [International Tech Park, Bangalore 560066, India] Mohan, Shyam [International Tech Park, Bangalore 560066, India] Padhukasahasram, Hariprasad [International Tech Park, Bangalore 560066, India] Subbannayya, Yashwanth [International Tech Park, Bangalore 560066, India] Goel, Renu [International Tech Park, Bangalore 560066, India] Jacob, Harrys KC [International Tech Park, Bangalore 560066, India] Sekhar, Raja [International Tech Park, Bangalore 560066, India] Vishalakshi, Nanjappa [International Tech Park, Bangalore 560066, India] Balakrishnan, Lavanaya [International Tech Park, Bangalore 560066, India] Subbaiah, Roopashree [International Tech Park, Bangalore 560066, India] Prasad, TS Keshava [International Tech Park, Bangalore 560066, India] Rahiman, B Abdul [Kuvempu University, Jnanasahyadri, Shimoga 577451, India] Lin, Jian-Xin [National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USA.] Renauld, Jean-Christophe [UCL] Constantinescu, Stefan N. [UCL] Ohara, Osamu [RIKEN Yokohama Institute, Kanagawa 230-0045, Japan] Hirano, Oshio [Osaka University, Osaka 565-0871, Japan] Kubo, Masato [Tokyo University of Science, Yamazaki, Noda City, Chiba 278-0022, Japan] Singh, Sujay [IMGENEX India Pvt. Ltd., Bhubaneswar, Orissa 92121, India] Sander, Chris [Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA] Leonard, Warren J [National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USA] Pandey, Akhilesh [Johns Hopkins University, Baltimore, Maryland 21205, USA] et al.[show all]

We have developed NetPath as a resource of curated human signaling pathways. As an initial step, NetPath provides detailed maps of a number of immune signaling pathways, which include approximately 1,600 reactions annotated from the literature and more than 2,800 instances of transcriptionally regulated genes - all linked to over 5,500 published articles. We anticipate NetPath to become a consolidated resource for human signaling pathways that should enable systems biology approaches.