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Characterization of the CtsR stress response regulon in Lactobacillus plantarum.

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Fiocco, Daniela Capozzi, Vittorio Collins, Michael Gallone, Anna Hols, Pascal [UCL] Spano, Giuseppe

Lactobacillus plantarum ctsR was characterized. ctsR was found to be cotranscribed with clpC and induced in response to various abiotic stresses. ctsR deletion conferred a heat-sensitive phenotype with peculiar cell morphological features. The transcriptional pattern of putative CtsR regulon genes was examined in the DeltactsR mutant. Direct CtsR-dependent regulation was demonstrated by DNA-binding assays using recombinant CtsR and the promoters of ctsR-clpC operon and hsp1.

Type de document Article de périodique (Journal article) – Article de recherche – Journal Article, Research Support, Non-U.S. Gov't
Type d'accès Accès libre
Année de publication 2010
Langue Anglais
Information sur le périodique "Journal of bacteriology" - Vol. 192, no. 3, p. 896-900 (2010)
Peer reviewed oui
issn 0021-9193
e-issn 1098-5530
Statut de la publication Publié
Affiliations UCL - SC/BIOL - Département de biologie
MESH Subject Temperature ; Reverse Transcriptase Polymerase Chain Reaction ; Repressor Proteins - genetics - metabolism - physiology ; Regulon - genetics - physiology ; Protein Binding ; Promoter Regions, Genetic - genetics ; Microscopy, Atomic Force ; Lactobacillus plantarum - genetics - metabolism - ultrastructure ; Heat-Shock Proteins ; Gene Expression Regulation, Bacterial - genetics - physiology ; Bacterial Proteins - genetics - metabolism - physiology
Liens
Référence bibliographique Fiocco, Daniela ; Capozzi, Vittorio ; Collins, Michael ; Gallone, Anna ; Hols, Pascal ; et. al. Characterization of the CtsR stress response regulon in Lactobacillus plantarum.. In: Journal of bacteriology, Vol. 192, no. 3, p. 896-900 (2010)
Permalien http://hdl.handle.net/2078.1/28710