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Progressive tubulointerstitial nephropathy with hepatic involvement in an infant.

Onglets principaux

Henrot, B. Vermylen, Christiane [UCL] Caus, D Cosyns, Jean-Pierre [UCL] Gosseye, Serge [UCL] Verellen, Gaston [UCL] Cornu, Guy [UCL]

We describe an infant with renal and liver disease who died at the age of 10 months from chronic renal failure. Hepatosplenomegaly was present along with biochemical findings of cholestasis and cytolysis. The diagnosis of tubulointerstitial nephropathy with cortical microcysts associated with hepatic fibrosis was based upon laboratory, radiological, and histological data. This rarely described disorder is characterized by an early clinical onset and unfavourable progression to end-stage renal failure before the age of 2.

Type de document Article de périodique (Journal article) – Case Reports, Journal Article, Review
Type d'accès Accès restreint
Année de publication 1990
Information sur le périodique "European journal of pediatrics" - Vol. 149, no. 5, p. 365-7 (1990)
Peer reviewed oui
issn 0340-6199
Statut de la publication Publié
Affiliations UCL - MD/MNOP - Département de morphologie normale et pathologique
MESH Subject Humans ; Infant ; Kidney - abnormalities - pathology ; Kidney Failure, Chronic - complications ; Liver - pathology ; Liver Cirrhosis - complications ; Male ; Nephritis, Interstitial - complications
Liens
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Référence bibliographique Henrot, B. ; Vermylen, Christiane ; Caus, D ; Cosyns, Jean-Pierre ; Gosseye, Serge ; et. al. Progressive tubulointerstitial nephropathy with hepatic involvement in an infant.. In: European journal of pediatrics, Vol. 149, no. 5, p. 365-7 (1990)
Permalien http://hdl.handle.net/2078.1/26410