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Displaying 15 results.
    • Journal article
    Kinetic properties of fructose bisphosphate aldolase from Trypanosoma brucei compared to aldolase from rabbit muscle and Staphylococcus aureus.
    Callens, M. Kuntz, D A Opperdoes, Frederik[UCL] (1991) Molecular and biochemical parasitology — Vol. 47, no. 1, p. 1-9 (1991)
    • Journal article
    High-level expression of Trypanosoma brucei fructose-1,6-bisphosphate aldolase in Escherichia coli and purification of the enzyme.
    Chevalier, Nathalie[UCL] Callens, M. Michels, Paulus[UCL] (1995) Protein expression and purification — Vol. 6, no. 1, p. 39-44 (1995)
    • Journal article
    Inhibition of the glycolytic enzymes in the trypanosome: an approach in the development of new leads in the therapy of parasitic diseases.
    Perié, J. Riviere-Alric, I Blonski, C. Gefflaut, T. Lauth de Viguerie, N Trinquier, M. Willson, M. Opperdoes, Frederik[UCL] Callens, M. (1993) Pharmacology & therapeutics — Vol. 60, no. 2, p. 347-65 (1993)
    • Journal article
    Chemical modification of fructose bisphosphate aldolase from Trypanosoma brucei compared to aldolase from rabbit muscle and Staphylococcus aureus.
    Callens, M. Opperdoes, Frederik[UCL] (1991) Molecular and biochemical parasitology — Vol. 47, no. 1, p. 11-7 (1991)
    • Journal article
    Selective interaction of glycosomal enzymes from Trypanosoma brucei with hydrophobic cyclic hexapeptides.
    Callens, M. Van Roy, Joris[UCL] Zeelen, J P Borchert, T V Nalis, D Wierenga, R K Opperdoes, Frederik[UCL] (1993) Biochemical and biophysical research communications — Vol. 195, no. 2, p. 667-72 (1993)
    • Journal article
    Synthesis and activity of inhibitors highly specific for the glycolytic enzymes from Trypanosoma brucei.
    Willson, M. Callens, M. Kuntz, D A Perié, J Opperdoes, Frederik[UCL] (1993) Molecular and biochemical parasitology — Vol. 59, no. 2, p. 201-10 (1993)
    • Journal article
    Some kinetic properties of pyruvate kinase from Trypanosoma brucei.
    Callens, M. Opperdoes, Frederik[UCL] (1992) Molecular and biochemical parasitology — Vol. 50, no. 2, p. 235-43 (1992)
    • Journal article
    Purification and characterisation of the phosphoglycerate kinase isoenzymes of Trypanosoma brucei expressed in Escherichia coli.
    Zomer, A W Allert, S. Chevalier, Nathalie[UCL] Callens, M. Opperdoes, Frederik[UCL] Michels, Paulus[UCL] (1998) Biochimica et biophysica acta — Vol. 1386, no. 1, p. 179-88 (1998)
    • Journal article
    The rational design of trypanocidal drugs: selective inhibition of the glyceraldehyde-3-phosphate dehydrogenase in Trypanosomatidae.
    Callens, M. Hannaert, Véronique[UCL] (1995) Annals of tropical medicine and parasitology — Vol. 89 Suppl 1, p. 23-30 (1995)
    • Journal article
    Cloning and characterization of the NAD-linked glycerol-3-phosphate dehydrogenases of Trypanosoma brucei brucei and Leishmania mexicana mexicana and expression of the trypanosome enzyme in Escherichia coli.
    Kohl, L. Drmota, T. Thi, C D[UCL] Callens, M. Van Beeumen, J. Opperdoes, Frederik[UCL] Michels, Paulus[UCL] (1996) Molecular and Biochemical Parasitology — Vol. 76, no. 1-2, p. 159-173 (1996)
    • Journal article
    Specific inhibitors for the glycolytic enzymes of Trypanosoma brucei.
    Trinquier, M. Perié, J. Callens, M. Opperdoes, Frederik[UCL] Willson, M. (1995) Bioorganic & medicinal chemistry — Vol. 3, no. 11, p. 1423-7 (1995)
    • Journal article
    Structure of the complex between trypanosomal triosephosphate isomerase and N-hydroxy-4-phosphono-butanamide: binding at the active site despite an "open" flexible loop conformation.
    Verlinde, C L Witmans, C J Pijning, T Kalk, K H Hol, W G Callens, M. Opperdoes, Frederik[UCL] (1992) Protein science : a publication of the Protein Society — Vol. 1, no. 12, p. 1578-84 (1992)
    • Journal article
    Characterization of pyruvate kinase of Trypanosoma brucei and its role in the regulation of carbohydrate metabolism.
    Callens, M. Kuntz, D A Opperdoes, Frederik[UCL] (1991) Molecular and biochemical parasitology — Vol. 47, no. 1, p. 19-29 (1991)
    • Journal article
    Pyruvate kinase of Trypanosoma brucei: overexpression, purification, and functional characterization of wild-type and mutated enzyme.
    Ernest, I. Callens, M. Uttaro, Antonio D Chevalier, Nathalie[UCL] Opperdoes, Frederik[UCL] Muirhead, H Michels, Paulus[UCL] (1998) Protein expression and purification — Vol. 13, no. 3, p. 373-82 (1998)
    • Journal article
    Overexpression of trypanosomal triosephosphate isomerase in Escherichia coli and characterisation of a dimer-interface mutant.
    Borchert, T V Pratt, K Zeelen, J P Callens, M. Noble, M E Opperdoes, Frederik[UCL] Michels, Paulus[UCL] Wierenga, R K (1993) European journal of biochemistry / FEBS — Vol. 211, no. 3, p. 703-10 (1993)