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Displaying 8 results.
    • Journal article
    Recessive primary congenital lymphoedema caused by a VEGFR3 mutation
    Ghalamkarpour, Arrask[UCL] Holnthoner, Wolfgang Saharinen, Pipsa Boon, Laurence M.[UCL] Mulliken, John B. Alitalo, Kari Vikkula, Miikka[UCL] (2009) Journal of Medical Genetics — Vol. 46, no. 6, p. 399-404 (2009)
    • Journal article
    Lymphatic malformations: genetics, mechanisms and therapeutic strategies.
    Mäkinen, Taija Boon, Laurence M.[UCL] Vikkula, Miikka[UCL] Alitalo, Kari (2021) Circulation research — Vol. 129, no. 1, p. 136-154 (2021)
    • Journal article
    Characterization of ANGPT2 mutations associated with primary lymphedema
    Leppänen, Veli-Matti Brouillard, Pascal[UCL] Korhonen, Emilia A Sipilä, Tuomas Jha, Sawan Kumar Revencu, Nicole[UCL] Labarque, Veerle Fastré, Elodie[UCL] Schlögel, Matthieu[UCL] Ravoet, Marie[UCL] Singer, Amihood Luzzatto, Claudia Angelone, Donatella Crichiutti, Giovanni D'Elia, Angela Kuurne, Jaakko Elamaa, Harri Koh, Gou Young Saharinen, Pipsa Vikkula, Miikka[UCL] Alitalo, Kari (2020) Science translational medicine — Vol. 12, no. 560, p. eaax8013 [1-11] (2020)
    • Journal article
    Blockade of VEGF-C signaling inhibits lymphatic malformations driven by oncogenic PIK3CA mutation.
    Martinez-Corral, Ines Zhang, Yan Petkova, Milena Ortsäter, Henrik Sjöberg, Sofie Castillo, Sandra D Brouillard, Pascal[UCL] Libbrecht, Louis[UCL] Saur, Dieter Graupera, Mariona Alitalo, Kari Boon, Laurence M.[UCL] Vikkula, Miikka[UCL] Mäkinen, Taija (2020) Nature communications — Vol. 11, no. 1, p. 2869 [1-14] (2020)
    • Journal article
    Ligand oligomerization state controls Tie2 receptor trafficking and angiopoietin-2-specific responses.
    Pietilä, Riikka Nätynki, Marjut Tammela, Tuomas Kangas, Jaakko Pulkki, Kristina H Limaye, Nisha Vikkula, Miikka Koh, Gou Young Saharinen, Pipsa Alitalo, Kari Eklund, Lauri (2012) Journal of Cell Science — Vol. 125, no.Pt 9, p. 2212-23 (2012)
    • BookChapter
    Angiopoietins, TIEs, Ephrins, VEGFs and VEGFRs
    Vikkula, Miikka[UCL] Karkkainen, Marika J. Alitalo, Kari (2004) Inborn errors of development: the molecular basis of clinical disorders on morphogenesis — [ISBN : 0-19-514502-X]
    • Journal article
    Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1
    Jha, Kumar Sawan Rauniyar, Khushbu Karpanen, Terhi Leppanen, Veli-Matti Brouillard, Pascal[UCL] Vikkula, Miikka[UCL] Alitalo, Kari Jeltsch, Michael (2017) Scientific reports — Vol. 7, no. 1, p. 4916 [1-13] (2017)
    • Journal article
    Congenital hereditary lymphedema caused by a mutation that inactivates VEGFR3 tyrosine kinase.
    Irrthum, A Alitalo, Kari Karkkainen, M J Devriendt, Koenraad[UCL] Vikkula, Miikka[UCL] (2000) American journal of human genetics — Vol. 67, no. 2, p. 295-301 (2000)