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Displaying 17 results.
    • Journal article
    Effect of acidic phospholipids on the activity of lysosomal phospholipases and on their inhibition by aminoglycoside antibiotics -- I. Biochemical analysis
    Mingeot-Leclercq, Marie-Paule[UCL] Piret, Jocelyne[UCL] Brasseur, Robert Tulkens, Paul M.[UCL] (1990) Biochemical Pharmacology — Vol. 40, no. 3, p. 489-497 (1990)
    • Journal article
    New derivatives of kanamycin B obtained by modifications and substitutions in position 6''. 2. In vitro and computer-aided toxicological evaluation with respect to interactions with phosphatidylinositol
    Mingeot-Leclercq, Marie-Paule[UCL] Van Schepdael, Ann[UCL] Brasseur, Robert Busson, Roger Vanderhaeghe, H J Claes, Paul[UCL] Tulkens, Paul M.[UCL] (1991) Journal of Medicinal Chemistry — Vol. 34, no. 4, p. 1476-1482 (1991)
    • Journal article
    Aminoglycoside antibiotics induce aggregation but not fusion of negatively-charged liposomes.
    Van Bambeke, Françoise[UCL] Tulkens, Paul M.[UCL] Brasseur, Robert Mingeot-Leclercq, Marie-Paule[UCL] (1995) European Journal of Pharmacology — Vol. 289, no. 2, p. 321-333 (1995)
    • Journal article
    Alterations in membrane permeability induced by aminoglycoside antibiotics: studies on liposomes and cultured cells
    Van Bambeke, Françoise[UCL] Mingeot-Leclercq, Marie-Paule[UCL] Schanck, André[UCL] Brasseur, Robert Tulkens, Paul M.[UCL] (1993) European Journal of Pharmacology — Vol. 247, no. 2, p. 155-168 (1993)
    • Journal article
    Interaction of the macrolide azithromycin with phospholipids. II. Biophysical and computer-aided conformational studies
    Montenez, Jean-Pierre[UCL] Van Bambeke, Françoise[UCL] Piret, Jocelyne[UCL] Schanck, André[UCL] Brasseur, Robert Tulkens, Paul M.[UCL] Mingeot-Leclercq, Marie-Paule[UCL] (1996) European Journal of Pharmacology — Vol. 314, no. 1-2, p. 215-227 (1996)
    • Journal article
    Aminoglycoside antibiotics prevent the formation of non-bilayer structures in negatively-charged membranes. Comparative studies using fusogenic (bis(beta-diethylaminoethylether)hexestrol) and aggregating (spermine) agents
    Van Bambeke, Françoise[UCL] Mingeot-Leclercq, Marie-Paule[UCL] Brasseur, Robert Tulkens, Paul M.[UCL] Schanck, André[UCL] (1996) Chemistry and Physics of Lipids — Vol. 79, no. 2, p. 123-135 (1996)
    • Journal article
    Synthesis and antimicrobial and toxicological studies of amino acid and peptide derivatives of kanamycin A and netilmicin
    Kotretsou, S Mingeot-Leclercq, Marie-Paule[UCL] Constantinou-Kokotou, V Brasseur, Robert Georgiadis, M P Tulkens, Paul M.[UCL] (1995) Journal of Medicinal Chemistry — Vol. 38, no. 23, p. 4710-4719 (1995)
    • Journal article
    Interactions of macrolide antibiotics (Erythromycin A, roxithromycin, erythromycylamine [Dirithromycin], and azithromycin) with phospholipids: computer-aided conformational analysis and studies on acellular and cell culture models
    Montenez, Jean-Pierre[UCL] Van Bambeke, Françoise[UCL] Piret, Jocelyne[UCL] Brasseur, Robert Tulkens, Paul M.[UCL] Mingeot-Leclercq, Marie-Paule[UCL] (1999) Toxicology and Applied Pharmacology : for those working in the fields of toxicology, pharmacology, biochemistry, nutrition, veterinary medicine — Vol. 156, no. 2, p. 129-140 (1999)
    • Journal article
    Interactions of ciprofloxacin with DPPC and DPPG
    Bensikaddour, Hayet[UCL] Snoussi, Karim[UCL] Lins, Laurence Van Bambeke, Françoise[UCL] Tulkens, Paul M.[UCL] Brasseur, Robert Goormaghtigh, Erik Mingeot-Leclercq, Marie-Paule[UCL] (2008) BBA - Biomembranes — Vol. 1778, no. 11, p. 2535-2543 (2008)
    • Journal article
    Interactions of aminoglycosides with phosphatidylinositol - a N-15 nuclear-magnetic-resonance study
    Schanck, André[UCL] Brasseur, Robert Mingeot-Leclercq, Marie-Paule[UCL] Tulkens, Paul M.[UCL] (1992) Magnetic Resonance in Chemistry — Vol. 30, no. 1, p. 11-15 (1992)
    • Journal article
    Use of an in vitro model to assess aminoglycoside phospholipid interactions in relation to their nephrotoxicity
    Carlier, MB.[UCL] Brasseur, Robert Laurent, Guy[UCL] Mingeot-Leclercq, Marie-Paule[UCL] Ruysschaert, Jean-Marie Tulkens, Paul M.[UCL] (1986) Food and Chemical Toxicology — Vol. 24, no. 6-7, p. 815-816 (1986)
    • Journal article
    Accessibility of aminoglycosides, isolated and in interaction with phosphatidylinositol, to water. A conformational analysis using the concept of molecular hydrophobicity potential
    Mingeot-Leclercq, Marie-Paule[UCL] Tulkens, Paul M.[UCL] Brasseur, Robert (1992) Biochemical Pharmacology — Vol. 44, no. 10, p. 1967-1975 (1992)
    • Journal article
    Cell handling, membrane-binding properties, and membrane-penetration modeling approaches of pivampicillin and phthalimidomethylampicillin, two basic esters of ampicillin, in comparison with chloroquine and azithromycin
    Chanteux, Hugues[UCL] Paternotte, Isabelle[UCL] Mingeot-Leclercq, Marie-Paule[UCL] Brasseur, Robert Sonveaux, Etienne[UCL] Tulkens, Paul M.[UCL] (2003) Pharmaceutical Research — Vol. 20, no. 4, p. 624-631 (2003)
    • BookChapter
    Conformational and biochemical analysis of the interactions between phospholipids and aminoglycoside antibiotics in relation with their toxicity
    Tulkens, Paul M.[UCL] Mingeot-Leclercq, Marie-Paule[UCL] Laurent, Guy Brasseur, Robert (1990) Molecular Description of Biological Membrane Components by Computer Aided Conformational Analysis — [ISBN : 9780849363757]
    • Journal article
    Ultrastructural, physico-chemical and conformational study of the interactions of gentamicin and bis(beta-diethylaminoethylether) hexestrol with negatively-charged phospholipid layers
    Mingeot-Leclercq, Marie-Paule[UCL] Schanck, André[UCL] Ronveaux-Dupal, Marie-France[FUNDP] Deleers, Michel Brasseur, Robert Ruysschaert, Jean-Marie Laurent, Guy[UCL] Tulkens, Paul M.[UCL] (1989) Biochemical Pharmacology — Vol. 38, no. 5, p. 729-741 (1989)
    • Journal article
    Effect of acidic phospholipids on the activity of lysosomal phospholipases and on their inhibition induced by aminoglycoside antibiotics -- II. Conformational analysis
    Mingeot-Leclercq, Marie-Paule[UCL] Piret, Jocelyne[UCL] Tulkens, Paul M.[UCL] Brasseur, Robert (1990) Biochemical Pharmacology — Vol. 40, no. 3, p. 499-506 (1990)
    • Journal article
    New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation
    Vanschepdael, Ann Busson, Roger Vanderhaeghe, HJ. Claes, PJ. Verbist, L. Mingeot-Leclercq, Marie-Paule[UCL] Brasseur, Robert Tulkens, Paul M.[UCL] (1991) Journal of Medicinal Chemistry — Vol. 34, no. 4, p. 1483-1492 (1991)