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Displaying 9 results.
    • Journal article
    What is the role of amyloid precursor protein dimerization?
    Khalifa, Naouel Ben[UCL] Van Hees, Joanne[UCL] Tasiaux, Bernadette[UCL] Huysseune, Sandra[UCL] Smith, Steven O.[UCL] Constantinescu, Stefan N.[UCL] Octave, Jean-Noël[UCL] Kienlen-Campard, Pascal[UCL] (2010) Cell Adhesion and Migration — Vol. 4, no. 2, p. 268-272 (2010)
    • Journal article
    A helix-to-coil transition at the epsilon-cut site in the transmembrane dimer of the amyloid precursor protein is required for proteolysis.
    Sato, Takeshi Tang, Tzu-Chun Reubins, Gabriella Fei, Jeffrey Z Fujimoto, Taiki Kienlen-Campard, Pascal[UCL] Constantinescu, Stefan N.[UCL] Octave, Jean-Noël[UCL] Aimoto, Saburo Smith, Steven O. (2009) Proceedings of the National Academy of Sciences of the United States of America — Vol. 106, no. 5, p. 1421-6 (2009)
    • Journal article
    An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia
    Plo, Isabelle Zhang, Yanyan Le Couedic, Jean-Pierre Nakatake, Mayuka Boulet, Jean-Michel Itaya, Miki Smith, Steven O. Debili, Najet Constantinescu, Stefan N.[UCL] Vainchenker, William Louache, Fawzia de Botton, Stephane (2009) The Journal of Experimental Medicine — Vol. 206, no. 8, p. 1701-1707 (2009)
    • Journal article
    Glycines from the APP GXXXG/GXXXA transmembrane motifs promote formation of pathogenic AB oligomers in cells
    Decock, Marie[UCL] Stanga, Serena[UCL] Octave, Jean-Noël[UCL] Dewachter, Ilse[UCL] Smith, Steven O. Constantinescu, Stefan N.[UCL] Kienlen-Campard, Pascal[UCL] (2016) Frontiers in Aging Neuroscience — Vol. 8, p. 107 [1-15] (2016)
    • Journal article
    An amphipathic motif at the transmembrane-cytoplasmic junction prevents autonomous activation of the thrombopoietin receptor.
    Staerk, Judith[UCL] Lacout, Catherine Sato, Takeshi Smith, Steven O. Vainchenker, William Constantinescu, Stefan N.[UCL] (2006) Blood — Vol. 107, no. 5, p. 1864-71 (2006)
    • Journal article
    Amyloidogenic processing but not amyloid precursor protein (APP) intracellular C-terminal domain production requires a precisely oriented APP dimer assembled by transmembrane GXXXG motifs
    Kienlen-Campard, Pascal[UCL] Tasiaux, Bernadette[UCL] Van Hees, Joanne[UCL] Li, Mingli[UCL] Huysseune, Sandra[UCL] Sato, Takeshi Fei, Jeffrey Z Aimoto, Saburo Courtoy, Pierre J.[UCL] Smith, Steven O. Constantinescu, Stefan N.[UCL] Octave, Jean-Noël[UCL] (2008) Journal of Biological Chemistry — Vol. 283, no. 12, p. 7733-7744 (2008)
    • Journal article
    Dimeric Transmembrane Orientations of APP/C99 Regulate γ-Secretase Processing Line Impacting Signaling and Oligomerization
    Perrin, Florian[UCL] Papadopoulos, Nicolas[UCL] Suelves Caballol, Nuria[UCL] Opsomer, Remi[UCL] Vadukul, Devkee Mahesh[UCL] Vrancx, Céline[UCL] Smith, Steven O. Vertommen, Didier[UCL] Kienlen-Campard, Pascal[UCL] Constantinescu, Stefan N.[UCL] (2020) iScience — Vol. 23, no. 12, p. 101887 [1-43] (2020)
    • Journal article
    Inhibitors of amyloid toxicity based on beta-sheet packing of Abeta40 and Abeta42.
    Sato, Takeshi Kienlen-Campard, Pascal[UCL] Ahmed, Mahiuddin Liu, Wei Li, Huilin Elliott, James I Aimoto, Saburo Constantinescu, Stefan N.[UCL] Octave, Jean-Noël[UCL] Smith, Steven O. (2006) Biochemistry — Vol. 45, no. 17, p. 5503-16 (2006)
    • Journal article
    Helix packing and orientation in the transmembrane dimer of gp55-P of the spleen focus forming virus
    Liu, Wei Crocker, Evan Constantinescu, Stefan N.[UCL] Smith, Steven O. (2005) Biophysical Journal — Vol. 89, no. 2, p. 1194-1202 (2005)