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Displaying 9 results.
    • Journal article
    Rituximab versus tocilizumab and B-cell status in TNF-alpha inadequate-responder rheumatoid arthritis patients: the R4-RA RCT
    Humby, Frances Durez, Patrick[UCL] Buch, Maya H Lewis, Myles J Bombardieri, Michele John, Christopher Rizvi, Hasan Warren, Louise Peel, Joanna Fossati-Jimack, Liliane Hands, Rebecca E Giorli, Giovanni Rivellese, Felice Cañete, Juan D Taylor, Peter C Sasieni, Peter Fonseca, João E Choy, Ernest Pitzalis, Costantino (2022) Efficacy and Mechanism Evaluation — Vol. 9, no.7, p. 1-58 (2022)
    • Journal article
    Patient-reported outcomes and safety in patients undergoing synovial biopsy: comparison of ultrasound-guided needle biopsy, ultrasound-guided portal and forceps and arthroscopic-guided synovial biopsy techniques in five centres across Europe.
    Just, Søren Andreas Humby, Frances Lindegaard, Hanne Meric de Bellefon, Laurent Durez, Patrick[UCL] Vieira-Sousa, Elsa Teixeira, Rui Stoenoiu, Maria[UCL] Werlinrud, Jens Rosmark, Sofie Larsen, Pia Veldt Pratt, Arthur Choy, Ernest Gendi, Nagui Buch, Maya H Edwards, Christopher J Taylor, Peter C McInnes, Iain B Fonseca, João Eurico Pitzalis, Costantino Filer, Andrew (2018) RMD open — Vol. 4, no.2, p. e000799 (2018)
    • Journal article
    EULAR points to consider for minimal reporting requirements in synovial tissue research in rheumatology.
    Najm, Aurélie Costantino, Félicie Alivernini, Stefano Alunno, Alessia Bianchi, Elettra Bignall, Jacqueline Boyce, Brendan Cañete, Juan D Carubbi, Francesco Durez, Patrick[UCL] Fonseca, João Eurico Just, Søren Andreas Largo, Raquel Manzo, Antonio Maybury, Mark Naredo, Esperanza Orr, Carl Pitzalis, Costantino Rivellese, Felice Romão, Vasco C van Rompay, Jef Tas, Sander W Veale, Douglas J D'Agostino, Maria-Antonietta Filer, Andrew (2022) Annals of the rheumatic diseases — Vol. 81, no. 12, p. 1640-1646 (2022)
    • Journal article
    Evaluation of Minimally Invasive, Ultrasound-guided Synovial Biopsy Techniques by the OMERACT Filter - Determining Validation Requirements.
    Humby, Frances Kelly, Stephen Bugatti, Serena Manzo, Antonio Filer, Andrew Mahto, Arti Fonseca, Joao Eurico Lauwerys, Bernard[UCL] D'Agostino, Maria-Antonietta Naredo, Esperanza Lories, Rik Montecucco, Carlomaurizio Tak, Paul Peter Fitzgerald, Oliver Smith, Malcolm D Veale, Douglas J Choy, Ernest H Strand, Vibeke Pitzalis, Costantino (2016) Journal of Rheumatology — Vol. 43, no. 1, p. 208-213 (2016)
    • Journal article
    Efficacy and safety of olokizumab in patients with rheumatoid arthritis with an inadequate response to TNF inhibitor therapy: outcomes of a randomised Phase IIb study
    Genovese, Mark C Fleischmann, Roy Furst, Daniel Janssen, Namieta Carter, John Dasgupta, Bhaskar Bryson, Judy Duncan, Benjamin Zhu, Wei Pitzalis, Costantino Durez, Patrick[UCL] Kretsos, Kosmas (2014) Annals of the Rheumatic Diseases — Vol. 73, no. 9, p. 1607-1615 (2014)
    • Journal article
    Rituximab versus tocilizumab in anti-TNF inadequate responder patients with rheumatoid arthritis (R4RA): 16-week outcomes of a stratified, biopsy-driven, multicentre, open-label, phase 4 randomised controlled trial.
    Humby, Frances Durez, Patrick[UCL] Buch, Maya H Lewis, Myles J Rizvi, Hasan Rivellese, Felice Nerviani, Alessandra Giorli, Giovanni Mahto, Arti Montecucco, Carlomaurizio Lauwerys, Bernard[UCL] Ng, Nora Ho, Pauline Bombardieri, Michele Romão, Vasco C Verschueren, Patrick Kelly, Stephen Sainaghi, Pier Paolo Gendi, Nagui Dasgupta, Bhaskar Cauli, Alberto Reynolds, Piero Cañete, Juan D Moots, Robert Taylor, Peter C Edwards, Christopher J Isaacs, John Sasieni, Peter Choy, Ernest Pitzalis, Costantino R4RA collaborative group (2021) Lancet — Vol. 397, no. 10271, p. 305-317 (2021)
    • Journal article
    Higher expression of TNFα-induced genes in the synovium of patients with early rheumatoid arthritis correlates with disease activity, and predicts absence of response to first line therapy.
    De Groof, Aurélie[UCL] Ducreux, Julie[UCL] Humby, Frances Nzeusseu Toukap, Adrien[UCL] Badot, Valérie Pitzalis, Costantino Houssiau, Frédéric[UCL] Durez, Patrick[UCL] Lauwerys, Bernard[UCL] (2016) Arthritis Research & Therapy (Online) — Vol. 18, no. 1, p. 19 [1-12] (2016)
    • Journal article
    Stratification of biological therapies by pathobiology in biologic-naive patients with rheumatoid arthritis (STRAP and STRAP-EU): two parallel, open-label, biopsy-driven, randomised trials.
    Rivellese, Felice Nerviani, Alessandra Giorli, Giovanni Warren, Louise Jaworska, Edyta Bombardieri, Michele Lewis, Myles J Humby, Frances Pratt, Arthur G Filer, Andrew Gendi, Nagui Cauli, Alberto Choy, Ernest McInnes, Iain Durez, Patrick[UCL] Edwards, Christopher J Buch, Maya H Gremese, Elisa Taylor, Peter C Ng, Nora Cañete, Juan D Raizada, Sabrina McKay, Neil D Jadon, Deepak Sainaghi, Pier Paolo Stratton, Richard Ehrenstein, Michael R Ho, Pauline Pereira, Joaquim P Dasgupta, Bhaskar Gorman, Claire Galloway, James Chinoy, Hector van der Heijde, Désirée Sasieni, Peter Barton, Anne Pitzalis, Costantino STRAP collaborative group (2023) The Lancet. Rheumatology — Vol. 5, no.11, p. e648-e659 (2023)
    • Journal article
    Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial.
    Rivellese, Felice Surace, Anna E A Goldmann, Katriona Sciacca, Elisabetta Çubuk, Cankut Giorli, Giovanni John, Christopher R Nerviani, Alessandra Fossati-Jimack, Liliane Thorborn, Georgina Ahmed, Manzoor Prediletto, Edoardo Church, Sarah E Hudson, Briana M Warren, Sarah E McKeigue, Paul M Humby, Frances Bombardieri, Michele Barnes, Michael R Lewis, Myles J Pitzalis, Costantino R4RA collaborative group Durez, Patrick[UCL] Lauwerys, Bernard[UCL] (2022) Nature medicine — Vol. 1, no.1, p. 1-33 (2022)