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Displaying 17 results.
    • Journal article
    Multivalent 9-O-Acetylated-sialic acid glycoclusters as potent inhibitors for SARS-CoV-2 infection
    Petitjean, Simon J. L.[UCL] Chen, Wenzhang Koehler, Melanie[UCL] Jimmidi, Ravikumar Yang, Jinsung[UCL] Mohammed, Danahe[UCL] Juniku, Blinera[UCL] Stanifer, Megan L. Boulant, Steeve Vincent, Stéphane P. Alsteens, David[UCL] (2022) Nature Communications — Vol. 13, no.1, p. 2564 (2022)
    • Journal article
    NgR1 binding to reovirus reveals an unusual bivalent interaction and a new viral attachment protein.
    Sutherland, Danica M Strebl, Michael Koehler, Melanie Welsh, Olivia L Yu, Xinzhe Hu, Liya Dos Santos Natividade, Rita[UCL] Knowlton, Jonathan J Taylor, Gwen M Moreno, Rodolfo A Wörz, Patrick Lonergan, Zachery R Aravamudhan, Pavithra Guzman-Cardozo, Camila Kour, Sukhleen Pandey, Udai Bhan Alsteens, David[UCL] Wang, Zhao Prasad, B V Venkataram Stehle, Thilo Dermody, Terence S (2023) Proceedings of the National Academy of Sciences of the United States of America — Vol. 120, no.24, p. e2219404120 (2023)
    • Journal article
    Altered Glycan Expression on Breast Cancer Cells Facilitates Infection by T3 Seroptype Oncolytic Reovirus
    Mohammed, Danahe[UCL] Koehler, Melanie[UCL] Dumitru, Andra-Cristina[UCL] Aravamudhan, Pavithra Sutherland, Danica M. Dermody, Terence S. Alsteens, David[UCL] (2021) Nano Letters — Vol. 21, no.22, p. 9720-9728 (2021)
    • Journal article
    Probing PIEZO1 Localization upon Activation Using High-Resolution Atomic Force and Confocal Microscopy
    Dumitru, Andra-Cristina[UCL] Stommen, Amaury[UCL] Koehler, Melanie[UCL] Cloos, Anne-Sophie[UCL] Yang, Jinsung[UCL] Leclercqz, Arnaud[UCL] Tyteca, Donatienne[UCL] Alsteens, David[UCL] (2021) Nano Letters — Vol. 21, no.12, p. 4950-4958 (2021)
    • Journal article
    Stepwise Enzymatic-Dependent Mechanism of Ebola Virus Binding to Cell Surface Receptors Monitored by AFM
    Zhang, Qingrong[UCL] Yang, Jinsung[UCL] Tillieux, Sueli[UCL] Guo, Zhengyuan Natividade, Rita dos Santos[UCL] Koehler, Melanie[UCL] Petitjean, Simon[UCL] Cui, Zongqiang Alsteens, David[UCL] (2022) Nano Letters — Vol. 22, no.4, p. 1641-1648 (2022)
    • Journal article
    Deciphering molecular mechanisms stabilizing the reovirus-binding complex.
    Dos Santos Natividade, Rita[UCL] Koehler, Melanie Gomes, Priscila S F C Simpson, Joshua[UCL] Smith, Sydni Caet Gomes, Diego E B de Lhoneux, Juliette[UCL] Yang, Jinsung[UCL] Ray, Ankita[UCL] Dermody, Terence S Bernardi, Rafael C Ogden, Kristen M Alsteens, David[UCL] (2023) Proceedings of the National Academy of Sciences of the United States of America — Vol. 120, no.21, p. e2220741120 (2023)
    • Journal article
    Atomic force microscopy applied to interrogate nanoscale cellular chemistry and supramolecular bond dynamics for biomedical applications
    Simpson, Joshua D.[UCL] Ray, Ankita[UCL] Koehler, Melanie[UCL] Mohammed, Danahe[UCL] Alsteens, David[UCL] (2022) Chemical Communications — Vol. 58, no.33, p. 5072-5087 (2022)
    • Journal article
    Single-Molecule Analysis of SARS-CoV-2 Binding to C-Type Lectin Receptors.
    Simpson, Joshua[UCL] Ray, Ankita[UCL] Marcon, Claire[UCL] Dos Santos Natividade, Rita[UCL] Dorrazehi, Gol Mohammad Durlet, Kimberley[UCL] Koehler, Melanie Alsteens, David[UCL] (2023) Nano letters — Vol. 23, no.4, p. 1496-1504 (2023)
    • Journal article
    Reovirus σ1 Conformational Flexibility Modulates the Efficiency of Host Cell Attachment.
    Diller, Julia R Halloran, Sean R Koehler, Melanie[UCL] Dos Santos Natividade, Rita[UCL] Alsteens, David[UCL] Stehle, Thilo Dermody, Terence S Ogden, Kristen M (2020) Journal of virology — Vol. 94, no.23, p. e01163-20 [1-18] (2020)
    • Journal article
    Submolecular probing of the complement C5a receptor–ligand binding reveals a cooperative two-site binding mechanism
    Dumitru, Andra-Cristina[UCL] Deepak, R. N. V. Krishna Liu, Heng Koehler, Melanie[UCL] Zhang, Cheng Fan, Hao Alsteens, David[UCL] (2020) Communications Biology — Vol. 3, no.1, p. 786 (2020)
    • Journal article
    Control of Ligand-Binding Specificity Using Photocleavable Linkers in AFM Force Spectroscopy
    Koehler, Melanie[UCL] Lo Giudice, Cristina[UCL] Vogl, Philipp Ebner, Andreas Hinterdorfer, Peter Gruber, Hermann J. Alsteens, David[UCL] (2020) Nano Letters — Vol. 20, no.5, p. 4038-4042 (2020)
    • Journal article
    Rotavirus Binding to Cell Surface Receptors Directly Recruiting α2 Integrin
    Yang, Jinsung[UCL] Park, Jeongsoo Koehler, Melanie[UCL] Simpson, Joshua[UCL] Luque, Daniel Rodríguez, Javier M. Alsteens, David[UCL] (2021) Advanced NanoBiomed Research — Vol. NaN, no. Nan, p. 2100077 (2021)
    • Journal article
    Molecular insights into receptor binding energetics and neutralization of SARS-CoV-2 variants
    Koehler, Melanie[UCL] Ray, Ankita[UCL] Moreira, Rodrigo A. Juniku, Blinera[UCL] Poma, Adolfo B. Alsteens, David[UCL] (2021) Nature Communications — Vol. 12, no.1 (2021)
    • Journal article
    Paired immunoglobulin-like receptor B is an entry receptor for mammalian orthoreovirus.
    Shang, Pengcheng Simpson, Joshua[UCL] Taylor, Gwen M Sutherland, Danica M Welsh, Olivia L Aravamudhan, Pavithra Dos Santos Natividade, Rita[UCL] Schwab, Kristina Michel, Joshua J Poholek, Amanda C Wu, Yijen Rajasundaram, Dhivyaa Koehler, Melanie Alsteens, David[UCL] Dermody, Terence S (2023) Nature communications — Vol. 14, no.1, p. 2615 (2023)
    • Journal article
    Single-Molecule Investigation of the Binding Interface Stability of SARS-CoV-2 Variants with ACE2
    Ray, Ankita[UCL] Minh Tran, Thu Thi Santos Natividade, Rita dos[UCL] Moreira, Rodrigo A. Simpson, Joshua D.[UCL] Mohammed, Danahe[UCL] Koehler, Melanie[UCL] Petitjean, Simon J.L.[UCL] Zhang, Qingrong[UCL] Bureau, Fabrice Gillet, Laurent Poma, Adolfo B. Alsteens, David[UCL] (2024) ACS Nanoscience Au — Vol. 4, no.2, p. 136-145 (2024)
    • Journal article
    Viral capsid structural assembly governs the reovirus binding interface to NgR1
    dos Santos Natividade, Rita[UCL] Dumitru, Andra-Cristina[UCL] Nicoli, Alessandro Strebl, Michael Sutherland, Danica M. Welsh, Olivia L. Ghulam, Mustafa Stehle, Thilo Dermody, Terence S. Di Pizio, Antonella Koehler, Melanie[UCL] Alsteens, David[UCL] (2024) Nanoscale Horizons — Vol. 9, no.11, p. 1925-1937 (2024)
    • Journal article
    Nanophysical Mapping of Inflammasome Activation by Nanoparticles via Specific Cell Surface Recognition Events
    Lo Giudice, Maria[UCL] Yang, Jinsung[UCL] Poncin, Mégane A.[UCL] Adumeau, Laurent Delguste, Martin[UCL] Koehler, Melanie[UCL] Evers, Koen Dumitru, Andra-Cristina[UCL] Dawson, Kenneth A. Alsteens, David[UCL] (2022) ACS Nano — Vol. 16, no.1, p. 306-316 (2021)