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1. • Journal article

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   Mechanism-based thrombin inhibitors: design, synthesis, and molecular docking of a new selective 2-oxo-2H-1-benzopyran derivative.

   Frédérick, Raphaël[UCL] Robert, S.[FUNDP] Charlier, Caroline[FUNDP] Wouters, Johan[FUNDP] Masereel, Bernard[FUNDP] Pochet, Lionel[FUNDP] (2007) Journal of medicinal chemistry — Vol. 50, no. 15, p. 3645-3650 (2007)
2. • Journal article

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   Investigation of mechanism-based thrombin inhibitors: Implications of a highly conserved water molecule for the binding of coumarins within the S pocket.

   Frédérick, Raphaël[UCL] Charlier, Caroline[FUNDP] Robert, S.[FUNDP] Wouters, Johan[FUNDP] Masereel, Bernard[FUNDP] Pochet, Lionel[FUNDP] (2006) Bioorganic & Medicinal Chemistry Letters : the tetrahedron journal for research at the interface of chemistry and biology — Vol. 16, no. 7, p. 2017-2021 (2006)
3. • Journal article

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   3,6-disubstituted coumarins as mechanism-based inhibitors of thrombin and factor Xa

   Frédérick, Raphaël[UCL] Robert, S.[FUNDP] Charlier, Caroline[FUNDP] de Ruyck, Jérôme Wouters, Johan[FUNDP] Pirotte, Bernard Masereel, Bernard[FUNDP] Pochet, Lionel[FUNDP] (2005) Journal of Medicinal Chemistry — Vol. 48, no. 24, p. 7592-7603 (2005)
4. • Journal article

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   Anomalous reactivity of benzopinacolone towards 4-phenylthiosemicarbazide, a nucleophile endowed with alpha-effect

   Kassehin, Comlan Urbain[UCL] Adjibode, Steeve A Bautista, Oscar[UCL] Gbaguidi, Fernand A Quetin-Leclercq, Joëlle[UCL] McCurdy, Christopher R Frédérick, Raphaël[UCL] Poupaert, Jacques[UCL] (2019) Journal of Medicinal and Chemical Sciences — Vol. 2, no.1, p. 17-20 (2019)
5. • Journal article

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   Convenient one-pot formation of highly functionalized 5-bromo-2-aminothiazoles, potential endocannabinoid hydrolase MAGL inhibitors

   Prevost, Julien R.C.[UCL] Kozlova, Arina[UCL] Es Saadi, Bouazza[UCL] Yildiz, Esra[UCL] Modaffari, Sara Lambert, Didier M.[UCL] Pochet, Lionel Wouters, Johan Dolušić, Eduard Frédérick, Raphaël[UCL] (2018) Tetrahedron Letters — Vol. 59, no.49, p. 4315-4319 (2018)
6. • Journal article

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   Current state on tryptophan 2,3-dioxygenase inhibitors: a patent review

   Kozlova, Arina[UCL] Frédérick, Raphaël[UCL] (2019) Expert Opinion on Therapeutic Patents — Vol. 29, no. 1, p. 11-23 (2019)
7. • Speech

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   Identification and development of LDH inhibitors to treat cancer

   Sonveaux, Pierre[UCL] Frédérick, Raphaël[UCL] (2021) Seminar Series of the European Institute of Chemistry and Biology (IECB) —
8. • Journal article

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   Olaparib is a mitochondrial Complex I inhibitor that kills temozolomide-resistant human glioblastoma cells

   Zampieri, Luca[UCL] Sboarina, Martina[UCL] Cacace, Andrea[UCL] Grasso, Debora[UCL] Thabault, Léopold[UCL] Hamelin, Loïc[UCL] Vazeille, Thibaut[UCL] Dumon, Elodie Rossignol, Rodrigue Frédérick, Raphaël[UCL] Sonveaux, Etienne[UCL] Lefranc, Florence Sonveaux, Pierre[UCL] (2021) International Journal of Molecular Sciences — Vol. 22, no.11938, p. 17 (2021)
9. • Patent

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   Lactate dehydrogenase inhibitor polypeptides for use in treatment of cancer

   Frédérick, Raphaël[UCL] Thabault, Léopold[UCL] Brisson, Lucie Copetti, Tamara Sonveaux, Pierre[UCL] (2019)
10. • Journal article

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    Interrogating the lactate dehydrogenase tetramerization site using (stapled) peptides.

    Thabault, Léopold[UCL] Brisson, Lucie[UCL] Brustenga, Chiara[UCL] Martinez Gache, Santiago A Prévost, Julien[UCL] Kozlova, Arina[UCL] Spillier, Quentin[UCL] Liberelle, Maxime[UCL] Benyahia, Zohra[UCL] Messens, Joris Copetti, Tamara[UCL] Sonveaux, Pierre[UCL] Frédérick, Raphaël[UCL] (2020) Journal of medicinal chemistry — Vol. 63, no.9, p. 4628-4643 (2020)
11. • Patent

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    Polypeptide inhibitors of lactate dehydrogenase activity for use in cancer therapy

    Sonveaux, Pierre[UCL] Thabault, Léopold[UCL] Liberelle, Maxime[UCL] Frédérick, Raphaël[UCL] (2021)
12. • Journal article

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    Pharmacomodulations of the benzoyl-thiosemicarbazide scaffold reveal antimicrobial agents targeting D-alanyl-D-alanine ligase in bacterio

    Ameryckx, Alice[UCL] Pochet, Lionel Wang, Gang[UCL] Yildiz, Esra[UCL] Es Saadi, Bouazza[UCL] Wouters, Johan Van Bambeke, Françoise[UCL] Frédérick, Raphaël[UCL] (2020) European Journal of Medicinal Chemistry — Vol. 200, no.1, p. 112444 (2020)
13. • Journal article

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    Unravelling the Allosteric Targeting of PHGDH at the ACT-Binding Domain with a Photoactivatable Diazirine Probe and Mass Spectrometry Experiments

    Spillier, Quentin[UCL] Ravez, Séverine Dochain Simon[UCL] Vertommen, Didier[UCL] Thabault, Léopold[UCL] Feron, Olivier[UCL] Frédérick, Raphaël[UCL] (2021) Molecules — Vol. 26, no. 2, p. 477 (2021)
14. • Journal article

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    The putative Escherichia coli dehydrogenase YjhC metabolises two dehydrated forms of N-acetylneuraminate produced by some sialidases

    Kentache, Takfarinas[UCL] Thabault, Léopold[UCL] Peracchi, Alessio Frédérick, Raphaël[UCL] Bommer, Guido[UCL] Van Schaftingen, Emile[UCL] (2020) Bioscience Reports — Vol. 40, no.6, p. 1-15 (2020)
15. • Journal article

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    1-(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting d-alanine-d-alanine ligase in bacterio

    Ameryckx, Alice[UCL] Thabault, Léopold[UCL] Pochet, Lionel Leimanis, Serge Poupaert, Jacques[UCL] Wouters, Johan Joris, Bernard Van Bambeke, Françoise[UCL] Frédérick, Raphaël[UCL] (2018) European Journal of Medicinal Chemistry — Vol. 159, p. 324-338 (2018)
16. • Journal article

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    The metalloprotein YhcH is an anomerase providing N-acetylneuraminate aldolase with the open form of its substrate

    Kentache, Takfarinas[UCL] Thabault, Léopold[UCL] Deumer, Gladys[UCL] Haufroid, Vincent[UCL] Frédérick, Raphaël[UCL] Linster, Carole Peracchi, Alessio[UCL] Veiga da Cunha, Maria[UCL] Bommer, Guido[UCL] Van Schaftingen, Emile[UCL] (2021) The Journal of biological chemistry — Vol. 296, p. 100699 [1-12] (2021)
17. • Journal article

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    Targeting protein self-association in drug design.

    Thabault, Léopold[UCL] Liberelle, Maxime[UCL] Frédérick, Raphaël[UCL] (2021) Drug Discovery Today — Vol. 26, no. 5, p. 1148-1163 (2021)
18. • Journal article

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    Structure–Activity Relationships (SARs) of α-Ketothioamides as Inhibitors of Phosphoglycerate Dehydrogenase (PHGDH)

    Spillier, Quentin[UCL] Ravez, Severine Unterlass, Judith Corbet, Cyril[UCL] Degavre, Charline[UCL] Feron, Olivier[UCL] Frédérick, Raphaël[UCL] (2020) Pharmaceuticals — Vol. 13, no.2, p. 20 (2020)
19. • Journal article

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    29ièmes Journées Franco-Belges de Pharmacochimie: Meeting Report

    The Members of the Organizing Committee Frédérick, Raphaël[UCL] Pochet, Lionel[FUNDP] De Tullio, Pascal Dufrasne, François E.[UCL] (2015) Pharmaceuticals — Vol. 8, no.4, p. 758-777 (2015)
20. • Journal article

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    α-Ketothioamide derivatives: a promising tool to interrogate the phosphoglycerate dehydrogenase (PHGDH).

    Ravez, Séverine Corbet, Cyril[UCL] Spillier, Quentin Dutu, Alice Robin, Anita D Mullarky, Edouard Cantley, Lewis Clayton Feron, Olivier[UCL] Frédérick, Raphaël (2017) Journal of Medicinal Chemistry — (2017)
21. • Journal article

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    31ièmes Journées Franco-Belges de Pharmacochimie: Meeting Report.

    Frédérick, Raphaël[UCL] Pochet, Lionel De Tullio, Pascal Dufrasne, François (2017) Pharmaceuticals — Vol. 10, p. 94 [1-12] (2017)
22. • Patent

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    Serine biosynthetic pathway inhibitors

    Frédérick, Raphaël[UCL] Ravez, Séverine[UCL] Spillier, Quentin[UCL] Corbet, Cyril[UCL] Feron, Olivier[UCL]
23. • Journal article

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    Challenges and Opportunities in the Development of Serine Synthetic Pathway Inhibitors for Cancer Therapy.

    Ravez, Séverine[UCL] Spillier, Quentin[UCL] Marteau, Romain[UCL] Feron, Olivier[UCL] Frédérick, Raphaël[UCL] (2017) Journal of Medicinal Chemistry — Vol. 60, no. 4, p. 1227-1237 (2017)
24. • Journal article

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    Tandem Heck/Tsuji-Trost Reaction for Uncaging of Alloc-Protected Amines with Palladium Complexes in Living Cells

    Tan, Yonghua[UCL] Lefevre, Marine[UCL] Pierrard, François[UCL] Soetens, Mathieu[UCL] Shoueiry, Maria[UCL] Yildiz, Esra[UCL] Ibanez, Sébastien[UCL] Ozkan, Kubra[UCL] Feron, Olivier[UCL] Frédérick, Raphaël[UCL] Riant, Olivier[UCL] (2023) Journal of Organometallic Chemistry — Vol. 996, no.-, p. 122743 (2023)
25. • Journal article

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    Tryptophan depletion sensitizes the AHR pathway by increasing AHR expression and GCN2/LAT1-mediated kynurenine uptake, and potentiates induction of regulatory T lymphocytes

    Solvay, Marie[UCL] Holfelder, Pauline Klaessens, Simon[UCL] Pilotte, Luc[UCL] Stroobant, Vincent[UCL] Lamy, Juliette Naulaerts, Stefan[UCL] Spillier, Quentin[UCL] Frédérick, Raphaël[UCL] De Plaen, Etienne[UCL] Sers, Christine Opitz, Christiane A Van den Eynde, Benoit[UCL] Zhu, Jingjing[UCL] (2023) Journal for ImmunoTherapy of Cancer — Vol. 11, no. 6, p. e006728 (2023)

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