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Speech

Knockout of the alpha 2 AMP-activated protein kinase isoform decreases the metabolic response of the heart to ischemia

Bertrand, Luc[UCL] Zarrinpshneh, E Ginion, Audrey[UCL] Beauloye, Christophe Vanoverschelde, Jean-Louis[UCL] Vaulont, S Viollet, B. Hue, Louis[UCL] (2004) 77th Scientific Meeting of the American-Heart-Association — New Orleans (La)

Journal article

Platelet Acetyl-CoA Carboxylase Phosphorylation A Risk Stratification Marker That Reveals Platelet-Lipid Interplay in Coronary Artery Disease Patients

Kautbally, Shakeel[UCL] Lepropre, Sophie[UCL] Onselaer, Marie-Blanche[UCL] Le Rigoleur, Astrid[UCL] Ginion, Audrey[UCL] De Meester de Ravenstein, Christophe[UCL] Ambroise, Jerome[UCL] Boudjeltia, Karim Z. Octave, Marie[UCL] Wéra, Odile Hego, Alexandre Pincemail, Joël Cheramy-Bien, Jean-Paul Huby, Thierry Giera, Martin Gerber, Bernhard[UCL] Pouleur, Anne-Catherine[UCL] Guigas, Bruno Vanoverschelde, Jean-Louis[UCL] Kefer, Joelle[UCL] Bertrand, Luc[UCL] Oury, Cécile Horman, Sandrine[UCL] Beauloye, Christophe[UCL] (2019) JACC: Basic to Translational Science — Vol. 4, no.5, p. 596-610 (2019)

Speech

Deletion of AMPK-Alpha2 intensifies the insulin-induced p70S6K activation in normoxic heart and the isoproterenol-induced ventricular hypertrophy

Zarrinpashneh, Elham[UCL] Beauloye, Christophe[UCL] Vanoverschelde, Jean-Louis[UCL] Ginion, Audrey[UCL] Pouleur, Anne-Catherine Horman, Sandrine[UCL] Hue, Louis[UCL] Viollet, Benoit Bertrand, Luc[UCL] (2006) 79th Annual Scientific Session of the American-Heart-Association — Chicago (Il)

Speech

Differential effects of AMPKa2 deletion on p70S6K pathway in normoxic and ischemic hearts and on the development of left ventricular hypertrophy

Zarrinpashneh, Elham[UCL] Beauloye, Christophe Ginion, Audrey[UCL] Pouleur, Anne-Catherine[UCL] Havaux, Xavier[UCL] Horman, Sandrine[UCL] Hue, Louis[UCL] Viollet, B. Vanoverschelde, Jean-Louis Bertrand, Luc[UCL] (2008) —

Speech

PDK1, but not PKB, is required for the activation of the Mtor/P70s6k pathway by leucine in the heart

Canedo, C. Sanchez[UCL] Beauloye, Christophe Demeulder, Bénédicte[UCL] Ginion, Audrey[UCL] Zarrinpashneh, Elham[UCL] Alessi, Dario R. Hue, Louis[UCL] Vanoverschelde, Jean-Louis Bertrand, Luc[UCL] (2008) —

Speech

The AMPK-induced p70S6K inhibition correlates to the synergistic effect of biguanides and insulin on glucose uptake via the overphosphorylation of the PKB/AS160 axis

Bertrand, Luc[UCL] Ginion, Audrey[UCL] Beauloye, Christophe Mouton, Céline[UCL] Hue, Louis[UCL] Vanoverschelde, Jean-Louis[UCL] (2007) 43rd Annual Meeting of the European-Association-for-the-Study-of-Diabetes — Amsterdam (Netherlands)

Speech

The AMPK-induced p70S6K inhibition participates in the synergistic effect of biguanides and insulin on glucose uptake via the overphosphorylation of the PKB/AS160 axis

Beauloye, Christophe[UCL] Vanoverschelde, Jean-Louis[UCL] Ginion, Audrey[UCL] Mouton, Céline[UCL] Hue, Louis[UCL] Bertrand, Luc[UCL] (2008) —

Speech

The activation of the AMP-activated protein kinase increases cardiac insulin sensitivity via multiple molecular mechanisms

Auquier, Julien[UCL] Ginion, Audrey[UCL] Hue, Louis[UCL] Horman, Sandrine[UCL] Beauloye, Christophe[UCL] Vanoverschelde, Jean-Louis[UCL] Bertrand, Luc[UCL] (2010) Conference on Frontiers in Cardiovascular Biology — Berlin (Germany)

Journal article

Fibroblast growth factor 23: a biomarker of fibrosis and prognosis in heart failure with preserved ejection fraction

Roy, Clotilde[UCL] Lejeune, Sibille[UCL] Slimani, Alisson[UCL] de Meester de Ravenstein, Christophe[UCL] Ahn, Sylvie A.[UCL] Rousseau, Michel[UCL] Amzulescu, Mihaela[UCL] Ginion, Audrey[UCL] Ferracin, Benjamin[UCL] Pasquet, Agnes[UCL] Vancraeynest, David[UCL] Beauloye, Christophe[UCL] Vanoverschelde, Jean-Louis[UCL] Horman, Sandrine[UCL] Gruson, Damien[UCL] Gerber, Bernhard[UCL] Pouleur, Anne-Catherine[UCL] (2020) ESC Heart Failure — Vol. 7, no. 5, p. 2494-2507 (2020)

Journal article

Metabolism and acetylation contribute to leucine-mediated inhibition of cardiac glucose uptake.

Renguet, Edith[UCL] Ginion, Audrey[UCL] Gélinas, Roselle[UCL] Bultot, Laurent[UCL] Auquier, Julien[UCL] Robillard Frayne, Isabelle Daneault, Caroline Vanoverschelde, Jean-Louis[UCL] Des Rosiers, Christine Hue, Louis[UCL] Horman, Sandrine[UCL] Beauloye, Christophe[UCL] Bertrand, Luc[UCL] (2017) American Journal of Physiology: Heart and Circulatory Physiology — Vol. 313, no. 2, p. H432-H445 (2017)

Journal article

AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation.

Gélinas, Roselle Mailleux, Florence[UCL] Dontaine, Justine[UCL] Bultot, Laurent[UCL] Demeulder, Bénédicte[UCL] Ginion, Audrey[UCL] Daskalopoulos, Evangelos-Panagiotis[UCL] Esfahani, Hrag[UCL] Dubois-Deruy, Emilie[UCL] Lauzier, Benjamin Gauthier, Chantal Olson, Aaron K Bouchard, Bertrand Des Rosiers, Christine Viollet, Benoit Sakamoto, Kei Balligand, Jean-Luc[UCL] Vanoverschelde, Jean-Louis[UCL] Beauloye, Christophe[UCL] Horman, Sandrine[UCL] Bertrand, Luc[UCL] (2018) Nature Communications — Vol. 9, no. 1, p. 374 [1-17] (2018)

Journal article

Sodium-myoinositol cotransporter-1, SMIT1, mediates the production of reactive oxygen species induced by hyperglycemia in the heart.

Van Steenbergen, Anne[UCL] Balteau, Magali[UCL] Ginion, Audrey[UCL] Ferté, Laura[UCL] Battault, Sylvain[UCL] de Meester de Ravenstein, Christophe[UCL] Balligand, Jean-Luc[UCL] Daskalopoulos, Evangelos-Panagiotis[UCL] Gilon, Patrick[UCL] Despa, Florin Despa, Sanda Vanoverschelde, Jean-Louis[UCL] Horman, Sandrine[UCL] Koepsell, Hermann Berry, Gerard Hue, Louis[UCL] Bertrand, Luc[UCL] Beauloye, Christophe[UCL] (2017) Scientific Reports — Vol. 7, p. 41166 [1-14] (2017)

Journal article

A-769662 potentiates the effect of other AMP-activated protein kinase activators on cardiac glucose uptake.

Timmermans, Aurélie[UCL] Balteau, Magali[UCL] Gélinas, Roselle[UCL] Renguet, Edith[UCL] Ginion, Audrey[UCL] de Meester, Carole[UCL] Sakamoto, Kei Balligand, Jean-Luc[UCL] Bontemps, Françoise[UCL] Vanoverschelde, Jean-Louis[UCL] Horman, Sandrine[UCL] Beauloye, Christophe[UCL] Bertrand, Luc[UCL] (2014) American journal of physiology. Heart and circulatory physiology — Vol. 306, no. 12, p. 1619-1630 (2014)

Journal article

Role of AMP-activated protein kinase in regulating hypoxic survival and proliferation of mesenchymal stem cells.

de Meester, Carole Timmermans, Aurélie[UCL] Balteau, Magali[UCL] Ginion, Audrey Roelants, Véronique Noppe, Gauthier Porporato, Paolo[UCL] Sonveaux, Pierre[UCL] Viollet, Benoît Sakamoto, Kei Feron, Olivier[UCL] Horman, Sandrine[UCL] Vanoverschelde, Jean-Louis[UCL] Beauloye, Christophe Bertrand, Luc[UCL] (2014) Cardiovascular Research — Vol. 101, no. 1, p. 20-29 (2014)

Journal article

Urocortin-induced cardiomyocytes hypertrophy is associated with regulation of the GSK-3β pathway

Gruson, Damien[UCL] Ginion, Audrey[UCL] Decroly, Noémie[UCL] Lause, Pascale[UCL] Vanoverschelde, Jean-Louis[UCL] Ketelslegers, Jean-Marie[UCL] Bertrand, Luc[UCL] Thissen, Jean-Paul[UCL] (2012) Heart and Vessels : an international journal — Vol. 27, no. 2, p. 202-207 (2012)

Journal article

AMPKalpha2 counteracts the development of cardiac hypertrophy induced by isoproterenol.

Zarrinpashneh, Elham[UCL] Beauloye, Christophe[UCL] Ginion, Audrey[UCL] Pouleur, Anne-Catherine[UCL] Havaux, Xavier[UCL] Hue, Louis[UCL] Viollet, Benoit Vanoverschelde, Jean-Louis[UCL] Bertrand, Luc[UCL] (2008) Biochemical and biophysical research communications — Vol. 376, no. 4, p. 677-81 (2008)

Journal article

Differential regulation of eEF2 and p70S6K by AMPKalpha2 in heart.

Demeulder, Bénédicte[UCL] Zarrinpashneh, Elham Ginion, Audrey[UCL] Viollet, Benoit Hue, Louis[UCL] Rider, Mark H.[UCL] Vanoverschelde, Jean-Louis[UCL] Beauloye, Christophe[UCL] Horman, Sandrine[UCL] Bertrand, Luc[UCL] (2013) BBA - Molecular Basis of Disease — Vol. 1832, no. 6, p. 780-790 (2013)

Journal article

NADPH oxidase activation by hyperglycaemia in cardiomyocytes is independent of glucose metabolism but requires SGLT1.

Balteau, Magali[UCL] Tajeddine, Nicolas[UCL] de Meester, Carole[UCL] Ginion, Audrey[UCL] Des Rosiers, Christine Brady, Nathan R Sommereyns, Caroline[UCL] Horman, Sandrine[UCL] Vanoverschelde, Jean-Louis[UCL] Gailly, Philippe[UCL] Hue, Louis[UCL] Bertrand, Luc[UCL] Beauloye, Christophe[UCL] (2011) Cardiovascular Research — Vol. 92, no. 2, p. 237-246 (2011)

Journal article

Inhibition of the mTOR/p70S6K pathway is not involved in the insulin-sensitizing effect of AMPK on cardiac glucose uptake.

Ginion, Audrey[UCL] Auquier, Julien[UCL] Benton, Carley R[UCL] Mouton, Céline[UCL] Vanoverschelde, Jean-Louis[UCL] Hue, Louis[UCL] Horman, Sandrine[UCL] Beauloye, Christophe[UCL] Bertrand, Luc[UCL] (2011) American Journal of Physiology: Heart and Circulatory Physiology — Vol. 301, no. 2, p. H469-77 (2011)

Journal article

Activation of the cardiac mTOR/p70(S6K) pathway by leucine requires PDK1 and correlates with PRAS40 phosphorylation

Canedo, Cossette Sanchez[UCL] Demeulder, Bénédicte[UCL] Ginion, Audrey[UCL] Bayascas, Jose R. Balligand, Jean-Luc[UCL] Alessi, Dario R. Vanoverschelde, Jean-Louis[UCL] Beauloye, Christophe[UCL] Hue, Louis[UCL] Bertrand, Luc[UCL] (2010) American Journal of Physiology: Endocrinology and Metabolism — Vol. 298, no. 4, p. E761-9 (2010)

Journal article

Role of the alpha2-isoform of AMP-activated protein kinase in the metabolic response of the heart to no-flow ischemia.

Zarrinpashneh, Elham[UCL] Carjaval, Karla Beauloye, Christophe[UCL] Ginion, Audrey[UCL] Mateo, Philippe Pouleur, Anne-Catherine[UCL] Horman, Sandrine[UCL] Vaulont, Sophie Hoerter, Jacqueline Viollet, Benoit Hue, Louis[UCL] Vanoverschelde, Jean-Louis[UCL] Bertrand, Luc[UCL] (2006) American journal of physiology. Heart and circulatory physiology — Vol. 291, no. 6, p. H2875-83 (2006)

Journal article

Urotensin II induction of adult cardiomyocytes hypertrophy involves the Akt/GSK-3beta signaling pathway.

Gruson, Damien[UCL] Ginion, Audrey[UCL] Decroly, Noémie[UCL] Lause, Pascale[UCL] Vanoverschelde, Jean-Louis[UCL] Ketelslegers, Jean-Marie[UCL] Bertrand, Luc[UCL] Thissen, Jean-Paul[UCL] (2010) Peptides — Vol. 31, no. 7, p. 1326-1333 (2010)

Journal article

AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B.

Bertrand, Luc[UCL] Ginion, Audrey[UCL] Beauloye, Christophe[UCL] Hebert, Alexandre[UCL] Guigas, Bruno[UCL] Hue, Louis[UCL] Vanoverschelde, Jean-Louis[UCL] (2006) American journal of physiology. Heart and circulatory physiology — Vol. 291, no. 1, p. H239-50 (2006)

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