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Displaying 24 results.
    • Journal article
    A phase 1 dose escalation study of the oncolytic adenovirus enadenotucirev, administered intravenously to patients with epithelial solid tumors (EVOLVE).
    Machiels, Jean-Pascal[UCL] Salazar, Ramon Rottey, Sylvie Duran, Ignacio Dirix, Luc Geboes, Karen Wilkinson-Blanc, Christine Pover, Gillian Alvis, Simon Champion, Brian Fisher, Kerry McElwaine-Johnn, Hilary Beadle, John Calvo, Emiliano (2019) Journal for immunotherapy of cancer — Vol. 7, no. 1, p. 20 [1-15] (2019)
    • Journal article
    Pembrolizumab versus methotrexate, docetaxel, or cetuximab for recurrent or metastatic head-and-neck squamous cell carcinoma (KEYNOTE-040): a randomised, open-label, phase 3 study.
    Cohen, Ezra E W Soulières, Denis Le Tourneau, Christophe Dinis, José Licitra, Lisa Ahn, Myung-Ju Soria, Ainara Machiels, Jean-Pascal[UCL] Mach, Nicolas Mehra, Ranee Burtness, Barbara Zhang, Pingye Cheng, Jonathan Swaby, Ramona F Harrington, Kevin J KEYNOTE-040 investigators (2019) Lancet — Vol. 393, no. 10167, p. 156-167 (2019)
    • Journal article
    Fibroblast Growth Factor Receptor-2 Polymorphism rs2981582 is Correlated With Progression-free Survival and Overall Survival in Patients With Metastatic Clear-cell Renal Cell Carcinoma Treated With Sunitinib.
    Vanmechelen, Maxime Lambrechts, Diether Van Brussel, Thomas Verbiest, Annelies Couchy, Gabrielle Schöffski, Patrick Dumez, Herlinde Debruyne, Philip R Lerut, Evelyne Machiels, Jean-Pascal[UCL] Richard, Vincent Albersen, Maarten Verschaeve, Vincent Oudard, Stéphane Méjean, Arnaud Wolter, Pascal Zucman-Rossi, Jessica Beuselinck, Benoit (2019) Clinical genitourinary cancer — Vol. 17, no. 2, p. e235-e246 (2019)
    • Journal article
    Neutropénie fébrile aux urgences, stratification du risque et conditions du retour à domicile
    Jacquet, Jonathan[UCL] Catala, Gaëtan Machiels, Jean-Pascal[UCL] Penaloza-Baeza, Andrea[UCL] (2019) Annales françaises de médecine d’urgence — Vol. 9, no.3, p. 173-183 (2019)
    • Journal article
    Tisotumab vedotin in patients with advanced or metastatic solid tumours (InnovaTV 201): a first-in-human, multicentre, phase 1-2 trial.
    de Bono, Johann S Concin, Nicole Hong, David S Thistlethwaite, Fiona C Machiels, Jean-Pascal[UCL] Arkenau, Hendrik-Tobias Plummer, Ruth Jones, Robert Hugh Nielsen, Dorte Windfeld, Kristian Ghatta, Srinivas Slomovitz, Brian M Spicer, James F Yachnin, Jeffrey Ang, Joo Ern Mau-Sørensen, Paul Morten Forster, Martin David Collins, Dearbhaile Dean, Emma Rangwala, Reshma A Lassen, Ulrik (2019) The Lancet. Oncology — Vol. 20, no. 3, p. 383-393 (2019)
    • Journal article
    Safety and Efficacy of Nivolumab Monotherapy in Recurrent or Metastatic Cervical, Vaginal, or Vulvar Carcinoma: Results From the Phase I/II CheckMate 358 Trial.
    Naumann, R Wendel Hollebecque, Antoine Meyer, Tim Devlin, Michael-John Oaknin, Ana Kerger, Joseph López-Picazo, Jose M Machiels, Jean-Pascal[UCL] Delord, Jean-Pierre Evans, Thomas R J Boni, Valentina Calvo, Emiliano Topalian, Suzanne L Chen, Tian Soumaoro, Ibrahima Li, Bin Gu, Junchen Zwirtes, Ricardo Moore, Kathleen N (2019) Journal of clinical oncology — Vol. 37, no. 31, p. 2825-2834 (2019)
    • Journal article
    Phase 1 Study Evaluating the Association of the Cyclin-Dependent Kinase 4/6 Inhibitor Ribociclib and Cetuximab in Recurrent/Metastatic p16-Negative Squamous Cell Carcinoma of the Head and Neck.
    Seront, Emmanuel Schmitz, Sandra[UCL] Papier, Matthias[UCL] van Maanen, Aline[UCL] Henry, Stéphanie Lonchay, Christophe Rottey, Sylvie van Caloen, Gabrielle Machiels, Jean-Pascal[UCL] (2019) Frontiers in oncology — Vol. 9, p. 155 [1-6] (2019)
    • Journal article
    May we rely on induction chemotherapy again as a biological selection of radiosensitive head and neck cancer?
    Bossi, Paolo Seront, Emmanuel Machiels, Jean-Pascal[UCL] (2019) Oral oncology — Vol. 94, no. 1, p. 121-122 (2019)
    • Journal article
    Afatinib as second-line treatment in patients with recurrent/metastatic squamous cell carcinoma of the head and neck: Subgroup analyses of treatment adherence, safety and mode of afatinib administration in the LUX-Head and Neck 1 trial.
    Haddad, Robert Guigay, Joel Keilholz, Ulrich Clement, Paul M Fayette, Jérôme de Souza Viana, Luciano Rolland, Frédéric Cupissol, Didier Geoffrois, Lionnel Kornek, Gabriela Licitra, Lisa Melichar, Bohuslav Ribaldo Nicolau, Ulisses Rauch, Daniel Zanetta-Devauges, Sylvie Cohen, Ezra E W Machiels, Jean-Pascal[UCL] Tahara, Makoto Vermorken, Jan Geng, Yuan Zografos, Eleftherios Gauler, Thomas (2019) Oral oncology — Vol. 97, p. 82-91 (2019)
    • Journal article
    Chimeric Antigen Receptor-T Cells for Targeting Solid Tumors: Current Challenges and Existing Strategies.
    Springuel, Lorraine Lonez, Caroline Alexandre, Bertrand Van Cutsem, Eric Machiels, Jean-Pascal[UCL] Van Den Eynde, Marc[UCL] Prenen, Hans Hendlisz, Alain Shaza, Leila Carrasco, Javier Canon, Jean-Luc Opyrchal, Mateusz Odunsi, Kunle Rottey, Sylvie Gilham, David E Flament, Anne Lehmann, Frédéric F (2019) BioDrugs — Vol. 33, no. 5, p. 515-537 (2019)
    • Journal article
    Comparative analysis of the phase III clinical trials of anti-PD1 monotherapy in head and neck squamous cell carcinoma patients (CheckMate 141 and KEYNOTE 040).
    Pai, Sara I Faivre, Sandrine Licitra, Lisa Machiels, Jean-Pascal[UCL] Vermorken, Jan B Bruzzi, Paolo Gruenwald, Viktor Giglio, Raul E Leemans, C René Seiwert, Tanguy Y Soulieres, Denis (2019) Journal for immunotherapy of cancer — Vol. 7, no. 1, p. 96 [1-4] (2019)
    • Journal article
    Potential role of cyclin-dependent kinase 4/6 inhibitors in the treatment of squamous cell carcinoma of the head and neck.
    van Caloen, Gabrielle[UCL] Machiels, Jean-Pascal[UCL] (2019) Current opinion in oncology — Vol. 31, no. 3, p. 122-130 (2019)
    • BookChapter
    Squamous Cell Carcinoma of the Head and Neck
    Seront Emmanuel Machiels, Jean-Pascal[UCL] Schmitz, Sandra[UCL] (2019) International Manual of Oncology Practice — [ISBN : 978-3-030-16244-3]
    • Speech
    A phase II study of Monalizumab in patients with recurrent/metastatic (RM) squamous cell carcinoma of the head and neck (SCCHN): results of the I1 cohort of the EORTC-HNCG-1559 trial (UPSTREAM).
    Galot, Rachel[UCL] Le Tourneau, C Saada-Bouzid, E Daste, A Even, C Debruyne, P Henry, S Zanetta, S Rutten, A Licitra, L Canon, JL Kaminsky, MC Specenier, P Rottey, S Dirix, L Raveloarivahy, T Fortpied, C Vanlancker, M Govaerts, A Machiels, Jean-Pascal[UCL] (2019) ESMO annual congress 2019 — (Sapin) Barcelona
    • Journal article
    ABCG2 Polymorphism rs2231142 and hypothyroidism in metastatic renal cell carcinoma patients treated with sunitinib.
    Werbrouck, Emilie Bastin, Julie Lambrechts, Diether Verbiest, Annelies Van Brussel, Thomas Lerut, Evelyne Machiels, Jean-Pascal[UCL] Verschaeve, Vincent Richard, Vincent Debruyne, Philip R Decallonne, Brigitte Schöffski, Patrick Bechter, Oliver Wolter, Pascal Beuselinck, Benoit (2019) Acta clinica Belgica — Vol. 74, no. 3, p. 180-188 (2019)
    • Journal article
    Combined PIK3CA and FGFR Inhibition With Alpelisib and Infigratinib in Patients With PIK3CA-Mutant Solid Tumors, With or Without FGFR Alterations.
    Hyman, David M Tran, Ben Paz-Ares, Luis Machiels, Jean-Pascal[UCL] Schellens, Jan H Bedard, Philippe L Campone, Mario Cassier, Philippe A Sarantopoulos, John Vaishampayan, Ulka Chugh, Rashmi Mahipal, Amit Lockhart, A Craig Sessa, Cristiana Zander, Thomas Ng, Matthew Curigliano, Giuseppe Bendiske, Jennifer Chen, Xueying Choudhury, Somesh Graus-Porta, Diana Lewis, Nancy Perez Garcia, Jose Manuel de Miguel-Luken, María José (2019) JCO precision oncology — Vol. 3, no.1, p. 1-13 (2019)
    • Speech
    Hyperpolarized pyruvate-lactate exchange assesses metabolic shift in response to the EGFR inhibitor Cetuximab in sensitive but not in resistant patient-derived HNSCC xenografts.
    Mignion, Lionel[UCL] Acciardo, Stefania[UCL] Gourgue, Florian[UCL] Joudiou, Nicolas[UCL] Caignet, Xavier[UCL] Goebbels, Rose-Marie Cani, Patrice D.[UCL] Machiels, Jean-Pascal[UCL] Schmitz, Sandra[UCL] Jordan, Bénédicte[UCL] (2019) 11th Annual Meeting of the ISMRM Benelux Chapter —
    • Speech
    Hyperpolarized pyruvate-lactate exchange assesses metabolic shift in response to the EGFR inhibitor Cetuximab in sensitive but not in resistant patient-derived HNSCC xenografts.
    Mignion, Lionel[UCL] Acciardo, Stefania[UCL] Gourgue, Florian[UCL] Joudiou, Nicolas[UCL] Caignet, Xavier[UCL] Goebbels, Rose-Marie Cani, Patrice D.[UCL] Schmitz, Sandra[UCL] Machiels, Jean-Pascal[UCL] Jordan, Bénédicte[UCL] (2019) European Molecular Imaging Meeting EMIM 2019 —
    • Journal article
    Amélioration du pronostic des patients grâce à l’utilisation de thérapeutiques innovantes dans des stades plus précoces
    Baurain, Jean-François[UCL] Machiels, Jean-Pascal[UCL] Duhoux, François[UCL] (2019) Louvain médical — Vol. 138, no.2, p. 119-125 (2019)
    • Speech
    Hyperpolarized pyruvate-lactate exchange assesses metabolic shift in response to the EGFR inhibitor cetuximab in sensitive but not in resistant patient-derived HNSCC xenografts
    Mignion, Lionel[UCL] Acciardo, Stefania[UCL] Gourgue, Florian[UCL] Joudiou, Nicolas[UCL] Caignet, Xavier[UCL] Goebbels Rose-Marie Corbet, Cyril[UCL] Feron, Olivier[UCL] Bouzin, Caroline[UCL] Cani, Patrice D.[UCL] Machiels, Jean-Pascal[UCL] Schmitz, Sandra[UCL] Jordan, Bénédicte[UCL] (2019) Belgian Molecular Imaging Congress 2019 —
    • Speech
    Co-segregation of rare possibly-damaging variants in cancer-related genes correlates with phenotypic homogeneity in familial breast cancer
    van Marcke, Cédric[UCL] Helaers, Raphaël[UCL] Schoonjans, Céline[UCL] Ambroise, Jérôme[UCL] Berlière, Martine[UCL] canon, Jean-Luc Vuylsteke, Peter[UCL] Machiels, Jean-Pascal[UCL] Vikkula, Miikka[UCL] Duhoux, François[UCL] (2019) San Antonio Breast Cancer Symposium — San Antonio
    • Speech
    Liquid biopsy for mutational profiling of locoregional recurrent (LR) and/or metastatic (M) squamous cell carcinoma of the head and neck (SCCHN)
    Galot, Rachel[UCL] van Marcke, Cédric[UCL] Helaers, Raphaël[UCL] Mendola, Antonella[UCL] Goebbels, Rose-Marie[UCL] Caignet, Xavier[UCL] Ambroise, Jérôme[UCL] Wittouck, Kyril[UCL] Vikkula, Miikka[UCL] Limaye, Nisha[UCL] Machiels, Jean-Pascal[UCL] (2019) ESMO — Barcelona
    • Speech
    Tumor sequencing is useful to reclassify germline variants in unexplained high-risk breast cancer
    van Marcke, Cédric[UCL] Helaers, Raphaël[UCL] Schoonjans, Céline[UCL] Berlière, Martine[UCL] De Leener, Anne[UCL] canon, Jean-Luc Vuylsteke, Peter[UCL] Machiels, Jean-Pascal[UCL] Limaye, Nisha[UCL] Vikkula, Miikka[UCL] Duhoux, François[UCL] (2019) San Antonio Breast Cancer Symposium — San Antonio
    • Journal article
    Intraoperative ketorolac in high-risk breast cancer patients. A prospective, randomized, placebo-controlled clinical trial
    Forget, Patrice Bouche, Gauthier Duhoux, Francois[UCL] Coulie, Pierre G.[UCL] Decloedt, Jan Dekleermaker, Alain Guillaume, Jean-Edouard[UCL] Ledent, Marc Machiels, Jean-Pascal[UCL] Mustin, Véronique Swinnen, Walter van Maanen, Aline[UCL] Vander Essen, Lionel Verougstraete, Jean-Christophe De Kock, Marc Berliere, Martine[UCL] (2019) PloS one — Vol. 14, no. 12, p. e0225748 [1-13] (2019)