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1. • Journal article

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   CYP3A4*22 genotype and systemic exposure affect paclitaxel-induced neurotoxicity.

   de Graan, Anne-Joy M Elens, Laure[UCL] Sprowl, Jason A Sparreboom, Alex Friberg, Lena E van der Holt, Bronno de Raaf, Pleun J de Bruijn, Peter Engels, Frederike K Eskens, Ferry A L M Wiemer, Erik A C Verweij, Jaap Mathijssen, Ron H J van Schaik, Ron H N (2013) Clinical Cancer Research — Vol. 19, no.12, p. 3316-3324 (2013)
2. • Speech

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   Companion diagnostics: Clinical significance of Pharmacogenetics, the concept of personalized therapy

   Elens, Laure[UCL] (2013) xSample Luminex Congress — Rotterdam, The Netherlands
3. • Journal article

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   Genetic variation in the PPARA gene is associated with simvastatin-mediated cholesterol reduction in the Rotterdam Study

   De Keyser, Catherine E Becker, Matthijs L Uitterlinden, André G Hofman, Albert Lous, Jan J Elens, Laure Visser, Loes E Van Schaik, Ron Hn Stricker, Bruno H (2013) Pharmacogenomics — Vol. 14, no. 11, p. 1295-1304 (2013)
4. • Speech

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   Impact of CYP3A4*22 allele on tacrolimus pharmacokinetics in early period after renal transplantation: Towards updated genotype-based dosing guidelines

   Elens, Laure[UCL] (2013) 13th International Congress of Therapeutic Drug Monitoring & Clinical Toxicology (IATDMCT) — Salt Lake City, USA
5. • Speech

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   Early Tacrolimus Dosing in Pediatric Liver Transplantation Depends on Recipient CYP3A5 and ABCB1 (or MDR1) Genotypes: Experience in Living Donor Recipients

   Elens, Laure[UCL] (2013) 13th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology — Salt lake city, USA
6. • Speech

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   Impact of POR*28 on the Pharmacokinetics of Tacrolimus and Cyclosporine A in Renal Transplant Patients

   Elens, Laure[UCL] (2013) 13th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology — Salt lake city usa
7. • Journal article

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   A pharmacogenetic predictive model for paclitaxel clearance based on the DMET platform.

   de Graan, Anne-Joy M Elens, Laure[UCL] Smid, Marcel Martens, John W Sparreboom, Alex Nieuweboer, Annemieke J M Friberg, Lena E Elbouazzaoui, Samira Wiemer, Erik A C van der Holt, Bronno Verweij, Jaap van Schaik, Ron H N Mathijssen, Ron H J (2013) Clinical Cancer Research — Vol. 19, no.18, p. 5210-5217 (2013)
8. • Journal article

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   The CYP3A4*22 allele affects the predictive value of a pharmacogenetic algorithm predicting tacrolimus predose concentrations

   Elens, Laure[UCL] Hesselink, Dennis A van Schaik, Ron H N van Gelder, Teun (2013) British Journal of Clinical Pharmacology — Vol. 75, no. 6, p. 1545-1547 (2013)
9. • Journal article

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   Single-nucleotide polymorphisms in P450 oxidoreductase and peroxisome proliferator-activated receptor-α are associated with the development of new-onset diabetes after transplantation in kidney transplant recipients treated with tacrolimus.

   Elens, Laure[UCL] Sombogaard, Ferdi Hesselink, Dennis A van Schaik, Ron H N van Gelder, Teun (2013) Pharmacogenetics and Genomics — Vol. 23, no.12, p. 649-657 (2013)
10. • Speech

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    A pharmacogenetic model predicting low paclitaxel clearance based on the DMET platform.

    Elens, Laure[UCL] (2013) Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO) — Chicago, USA
11. • Speech

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    TACROLIMUS FIRST DOSE DEPENDS ON RECIPIENT CYP3A5 AND ABCB1 (OR MDR1) GENOTYPES IN PEDIATRIC LIVER TRANSPLANTATION: EXPERIENCE IN LIVING DONOR RECIPIENTS

    Elens, Laure[UCL] (2013) 13th ESOT — Austria
12. • Speech

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    EARLY TACROLIMUS DOSING IN PEDIATRIC LIVER TRANSPLANTATION DEPENDS ON RECIPIENT CYP3A5 AND ABCB1 (or MDR1) GENOTYPES: EXPERIENCE IN LIVING DONOR RECIPIENTS

    Elens, Laure[UCL] (2013) International Pediatric Transplant Association — Mont Laurel, USA
13. • Journal article

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    Genetic variation in the ABCC2 gene is associated with dose decreases or switches to other cholesterol-lowering drugs during simvastatin and atorvastatin therapy.

    Becker, M L Elens, Laure[UCL] Visser, L E Hofman, A Uitterlinden, A G van Schaik, R H N Stricker, B H (2013) The Pharmacogenomics Journal — Vol. 13, no.3, p. 251-256 (2011)
14. • Speech

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    Impact of POR*28 on the clinical pharmacokinetics of CYP3A phenotyping probes midazolam and erythromycin

    Elens, Laure[UCL] (2013) 13th International Congress of Therapeutic Drug Monitoring & Clinical Toxicology (IATDMCT) — Salt Lake city, USA
15. • Speech

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    Pharmacogenetics of statins: Are we ready for the clinic?

    Elens, Laure[UCL] (2013) the Royal Belgian Society of Clinical Chemistry annual symposium — Brussels, Belgium
16. • Speech

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    Impact of POR*28 on the Clinical Pharmacokinetics of CYP3A Phenotyping Probes Midazolam and Erythromycin

    Elens, Laure[UCL] (2013) 13th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology — Salt Lake City, USA
17. • Journal article

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    The Val158Met polymorphism of the COMT gene is associated with increased pain sensitivity in morphine-treated patients undergoing a painful procedure after cardiac surgery.

    Ahlers, Sabine J G M Elens, Laure[UCL] van Gulik, Laura van Schaik, Ron H van Dongen, Eric P A Bruins, Peter Tibboel, Dick Knibbe, Catherijne A J (2013) British Journal of Clinical Pharmacology — Vol. 75, no.6, p. 1506-1515 (2013)
18. • Journal article

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    CYP3A4*22: promising newly identified CYP3A4 variant allele for personalizing pharmacotherapy

    Elens, Laure[UCL] van Gelder, Teun Hesselink, Dennis A Haufroid, Vincent[UCL] van Schaik, Ron H N (2013) Pharmacogenomics — Vol. 14, no. 1, p. 47-62 (2013)
19. • Journal article

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    Impact of POR*28 on the clinical pharmacokinetics of CYP3A phenotyping probes midazolam and erythromycin.

    Elens, Laure[UCL] Nieuweboer, Annemieke J M Clarke, Stephen J Charles, Kellie A de Graan, Anne-Joy M Haufroid, Vincent[UCL] van Gelder, Teun Mathijssen, Ron H J van Schaik, Ron H N (2013) Pharmacogenetics and Genomics — Vol. 23, no.3, p. 148-155 (2013)
20. • Journal article

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    Impact of CYP3A4*22 allele on tacrolimus pharmacokinetics in early period after renal transplantation: toward updated genotype-based dosage guidelines

    Elens, Laure[UCL] Capron, Arnaud[UCL] van Schaik, Ron H N De Meyer, Martine[UCL] De Pauw, Luc[UCL] Eddour, Djamila C[UCL] Latinne, Dominique[UCL] Wallemacq, Pierre[UCL] Mourad, Michel[UCL] Haufroid, Vincent[UCL] (2013) Therapeutic Drug Monitoring — Vol. 35, no. 5, p. 608-616 (2013)
21. • Journal article

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    CYP3A4 intron 6 C>T SNP (CYP3A4*22) encodes lower CYP3A4 activity in cancer patients, as measured with probes midazolam and erythromycin.

    Elens, Laure[UCL] Nieuweboer, Annemieke Clarke, Stephen J Charles, Kellie A de Graan, Anne-Joy Haufroid, Vincent Mathijssen, Ron H J van Schaik, Ron H N (2013) Pharmacogenomics — Vol. 14, no.2, p. 137-149 (2013)
22. • Journal article

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    CYP3A4intron 6 C>T SNP (CYP3A4*22) encodes lower CYP3A4 activity in cancer patients, as measured with probes midazolam and erythromycin

    Elens, Laure[UCL] Nieuweboer, Annemieke Clarke, Stephen J Charles, Kellie A de Graan, Anne-Joy Haufroid, Vincent[UCL] Mathijssen, Ron HJ van Schaik, Ron HN (2013) Pharmacogenomics — Vol. 14, no. 2, p. 137-149 (2013)
23. • Journal article

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    CYP3A4*22 and CYP3A combined genotypes both correlate with tacrolimus disposition in pediatric heart transplant recipients

    Gijsen, Violette Mgj Van Schaik, Ron Hn Elens, Laure Soldin, Offie P Soldin, Steven J Koren, Gideon De Wildt, Saskia N (2013) Pharmacogenomics — Vol. 14, no. 9, p. 1027-1036 (2013)
24. • Speech

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    Genetic Variation in the PPARA Gene Is Associated with Simvastatin-Mediated Cholesterol Reduction in the Rotterdam Study

    Elens, Laure[UCL] (2013) 29th International Conference on Pharmacoepidemiology & Therapeutic Risk Management — Montréal, Canada
25. • Speech

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    Single-nucleotide polymorphisms in P450 Oxidoreductase and Peroxisome Proliferator-Activated Receptor-α are associated with the development of new-onset diabetes after transplantation in kidney transplant recipients treated with tacrolimus.

    Elens, Laure[UCL] (2013) European Society for Organ transplantation (ESOT) annual Congress — Vienna, Austria

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