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Speech

Abnormalities at the level of gene-specific repair, chromatin condensation and transcriptional activity in different genomic loci predict clinical outcome in Multiple Myeloma.

Episkopou, Charikleia[UCL] (2009) 20th Congress of the Hellenic Society of Haematology — Crete

Journal article

TSPYL5 depletion induces specific death of ALT cells through USP7-dependent proteasomal degradation of POT1

Episkopou, Charikleia[UCL] Diman, Aurélie[UCL] Claude, Eloïse Laurie[UCL] Viceconte, Nikenza[UCL] Decottignies, Anabelle[UCL] (2019) Molecular Cell — Vol. 75, no. 3, p. 469-482 (2019)

Speech

TSPYL5 depletion induces specific death of ALT cells through USP7-dependent proteasomal degradation of POT1

Episkopou, Charikleia[UCL] Diman, Aurélie[UCL] Episkopou, Charikleia[UCL] Viceconte, Nikenza[UCL] Decottignies, Anabelle[UCL] (2019) Telomeres & Telomerase — Cold Spring Harbor USA

Journal article

Specific death of ALT cells through TSPYL5 depletion

Claude, Eloïse Laurie[UCL] Episkopou, Charikleia[UCL] Decottignies, Anabelle[UCL] (2019) Mol Cell Oncol — Vol. 6, no.6, p. e1651603 (2019)

Journal article

Photo-induced telomeric DNA damage in human cancer cells

Weynand, Justin[UCL] Episkopou, Charikleia[UCL] Le Berre, Gabriel[UCL] Gillard, Martin[UCL] Dejeu, Jérôme[UCL] Decottignies, Anabelle[UCL] Defrancq, Eric[UCL] Elias, Benjamin[UCL] (2022) RSC Chemical Biology — Vol. 3, no.12, p. 1375-1379 (2022)

Journal article

Development and validation of a PCR-based assay for the selection of patients more likely to benefit from therapeutic treatment with alkylating drugs.

Stefanou, Dimitra T Episkopou, Charikleia[UCL] Kyrtopoulos, Soterios A Bamias, Aristotelis Gkotzamanidou, Maria Bamia, Christina Liakou, Christina Bekyrou, Margarita Sfikakis, Petros P Dimopoulos, Meletios-Athanasios Souliotis, Vassilis L (2012) British Journal of Clinical Pharmacology — Vol. 74, no. 5, p. 842-853 (2012)

Speech

Alternative Lengthening of Telomeres is characterized by reduced compaction of telomeric chromatin.

Episkopou, Charikleia[UCL] (2014) EMBO Conference series: Telomeres, Telomerase and Disease — Brussels, Belgium

Speech

Repair of melphalan DNA adducts shows a general 5’ to 3’-end gradient effect in transcribed genes: Clinical implications

Episkopou, Charikleia[UCL] (2009) 39th Annual Meeting of the European Enviromental Mutagen Society — Firenze, Italy

Speech

The global genome repair sub pathway of nucleotide excision repair plays a crucial role in the repair of melphalan-induced monoadducts

Episkopou, Charikleia[UCL] (2006) 58th Meeting of Hellenic Society of Biochemistry & Molecular Biology — Patra, Greece

Journal article

The repair of melphalan-induced DNA adducts in the transcribed strand of active genes is subject to a strong polarity effect.

Episkopou, Charikleia[UCL] Kyrtopoulos, Soterios A Sfikakis, Petros P Dimopoulos, Meletios A Souliotis, Vassilis L (2011) Mutation Research — Vol. 714, no. 1-2, p. 78-87 (2011)

Speech

Alterations in the epigenetic network controlling transcription activity, chromatin structure and region-specific repair of different genomic loci predict clinical outcome in Multiple Myeloma

Episkopou, Charikleia[UCL] (2009) 51st ASH Annual Meeting and Exposition — New Orleans, USA

Speech

TSPYL5 prevents POT1 degradation in cells with an alternative mechanism of telomere maintenance

Episkopou, Charikleia[UCL] Diman, Aurélie[UCL] Viceconte, Nikenza[UCL] Decottignies, Anabelle[UCL] (2018) Telomere biology in health and human disease-EMBO Workshop. — Troia, Portugal

Speech

Testis Specific Y-encoded-Like Protein 5 prevents POT1 degradation in cells with an alternative mechanism of telomere maintenance

Episkopou, Charikleia[UCL] Diman, Aurélie[UCL] Claude, Eloïse Laurie[UCL] Viceconte, Nikenza[UCL] Decottignies, Anabelle[UCL] (2018) Telomere biology in health and human disease-EMBO Workshop. — Troia, Portugal

Speech

The global genome repair sub pathway of nucleotide excision repair plays a crucial role in the repair of melphalan-induced lesions

Episkopou, Charikleia[UCL] (2006) 36th Annual Meeting of the European Enviromental Mutagen Society — Prague

Journal article

Impaired telomere integrity and rRNA biogenesis in PARN-deficient patients and knock-out models

Benyelles, Maname Episkopou, Charikleia[UCL] O’Donohue, Marie-Françoise Kermasson, Laëtitia Frange, Pierre Poulain, Florian[UCL] Burcu Belen, Fatma Polat, Meltem Bole-Feysot, Christine Langa-Vives, Francina Gleizes, Pierre-Emmanuel de Villartay, Jean-Pierre Callebaut, Isabelle Decottignies, Anabelle[UCL] Revy, Patrick (2019) EMBO Molecular Medicine — Vol. June 6, no.June 6, p. e10201 (2019)

Speech

Development and validation of a multiplex, long quantitative PCR-based method to measure DNA adducts induced by chemotherapeutic agents in specific sequences, with clinical application potential

Episkopou, Charikleia[UCL] (2008) 38th Annual Meeting of the European Enviromental Mutagen Society — Cavtat, Croatia

Journal article

Preferential in vivo DNA repair of melphalan-induced damage in human genes is greatly affected by the local chromatin structure.

Souliotis, Vassilis L Dimopoulos, Meletios A Episkopou, Charikleia[UCL] Kyrtopoulos, Soterios A Sfikakis, Petros P (2006) DNA Repair — Vol. 5, no. 8, p. 972-985 (2006)

Journal article

Genetic inactivation of ATRX leads to a decrease in the amount of telomeric cohesin and of telomere transcription in human glioma cells

Eid, Rita Demattei, Marie-Véronique Episkopou, Charikleia[UCL] Augé-Gouillou, Corinne Decottignies, Anabelle[UCL] Grandin, Nathalie Charbonneau, Michel (2015) Molecular and Cellular Biology — Vol. 35, no. 16, p. 2818-2830 (2015)

Journal article

Alternative Lengthening of Telomeres is characterized by reduced compaction of telomeric chromatin.

Episkopou, Charikleia[UCL] Draskovic, Irena Van Beneden, Amandine[UCL] Tilman, Gaëlle[UCL] Mattiussi, Marina[UCL] Gobin, Matthieu[UCL] Arnoult, Nausica[UCL] Londoño-Vallejo, Arturo Decottignies, Anabelle[UCL] (2014) Nucleic Acids Research — Vol. 42, no.7, p. 4391-4405 (2014)

Speech

Close association between transcriptional activity, local chromatin structure and the efficiencies of both sub-pathways of nucleotide excision repair of melphalan-induced N-alkylpurines.

Episkopou, Charikleia[UCL] (2008) 38th Annual Meeting of the European Environmental Mutagen Society. — Cavtat, Croatia.

Journal article

Aberrant DNA damage response pathways may predict the outcome of platinum chemotherapy in ovarian cancer.

Stefanou, Dimitra T Bamias, Aristotelis Episkopou, Charikleia[UCL] Kyrtopoulos, Soterios A Likka, Maria Kalampokas, Theodore Photiou, Stylianos Gavalas, Nikos Sfikakis, Petros P Dimopoulos, Meletios A Souliotis, Vassilis L (2015) PLoS One — Vol. 10, no. 2, p. e0117654 [1-19] (2015)

Speech

Gene-specific repair of melphalan-induced DNA damage by global and transcription-coupled nucleotide excision repair

Episkopou, Charikleia[UCL] (2007) 59th Meeting of Hellenic Society of Biochemistry & Molecular Biology — Athens, Greece

Speech

Alternative lengthening of telomeres (ALT) is characterized by reduced compaction of telomeric chromatin.

Episkopou, Charikleia[UCL] Draskovic, Irena[UCL] Van Beneden, Amandine[UCL] Tilman, Gaëlle[UCL] Mattiussi, Marina[UCL] Gobin, Matthieu[UCL] Arnoult, Nausica[UCL] Londono-Vallejo, Arturo[UCL] Decottignies, Anabelle[UCL] (2014) Telomeres, Telomerase and Disease — Brussels, Belgium

Journal article

Association between transcriptional activity, local chromatin structure, and the efficiencies of both subpathways of nucleotide excision repair of melphalan adducts.

Episkopou, Charikleia[UCL] Kyrtopoulos, Soterios A Sfikakis, Petros P Fousteri, Maria Dimopoulos, Meletios A Mullenders, Leon H F Souliotis, Vassilis L (2009) Cancer Research — Vol. 69, no. 10, p. 4424-4433 (2009)

Speech

Abnormalities in the order of gene-specific repair, chromatin condensation and transcription activity in different genomic loci predict clinical outcome in Multiple Myeloma

Episkopou, Charikleia[UCL] (2009) 39th Annual Meeting of the European Enviromental Mutagen Society — Firenze, Italy

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