De Hertogh, Benoît
[UCL]
Carvajal, Elvira
Talla, Emmanuel
Dujon, Bernard
Baret, Philippe
[UCL]
Goffeau, André
[UCL]
On the basis of functional and phylogenetic criteria, we have identified a total of 229 subfamilies and 111 singletons predicted to carry out transport or other membrane functions in Saccharomyces cerevisiae. We have extended the Transporter Classification (TC) and created a Membrane Classification (MC) for non-transporter membrane proteins. Using the preliminary phylogenetic digits X, Y, Z (for new families, subfamilies, and clusters, respectively), we allocated a five-digit number to 850 proteins predicted to contain more than two transmembrane domains. Compared with a previous TC of the yeast genome, we classified an additional set of 538 membrane proteins (transporters and non-transporters) and identified 111 novel phylogenetic subfamilies.
Bibliographic reference |
De Hertogh, Benoît ; Carvajal, Elvira ; Talla, Emmanuel ; Dujon, Bernard ; Baret, Philippe ; et. al. Phylogenetic classification of transporters and other membrane proteins from Saccharomyces cerevisiae.. In: Functional & integrative genomics, Vol. 2, no. 4-5, p. 154-70 (2002) |
Permanent URL |
http://hdl.handle.net/2078.1/9223 |