Kadhim, Hazim
[UCL]
Tabarki, B
[UCL]
De Prez, C
Rona, Anne-Marie
[UCL]
Sébire, G
[UCL]
Proinflammatory cytokines were reported to be implicated in the pathogenesis of perinatal white matter lesions. The authors document for the first time the in situ detection of interleukin-2 and interleukin-2 receptor (IL-2R) in these human white matter lesions. These results suggest that interleukin-2, reported to be toxic to oligodendrocytes and myelin, could play a role in the molecular cascade leading to white matter damage in periventricular leukomalacia.
Bibliographic reference |
Kadhim, Hazim ; Tabarki, B ; De Prez, C ; Rona, Anne-Marie ; Sébire, G. Interleukin-2 in the pathogenesis of perinatal white matter damage.. In: Neurology, Vol. 58, no. 7, p. 1125-1128 (2002) |
Permanent URL |
http://hdl.handle.net/2078.1/9124 |