Dechamps, Monique
[UCL]
Sonveaux, Etienne
[UCL]
new nucleoside analogs with a masked aldehyde function have been synthesized and incorporated in oligodexoyribonucleotides. After unmasking the aldehyde function, the oligomers were easily coupled to biotin derivatives by reductive amination. Reversed phase HPLC proved to be an unvaluable tool to characterize and purify these conjugates.
Bibliographic reference |
Dechamps, Monique ; Sonveaux, Etienne. Aldehyde Functions in Synthetic Oligonucleotides.11th International Round Table on Nucleosides, Nucleotides and Their Biological Applications (KATHOLIEK UNIV LEUVEN, LEUVEN
(Belgium), Sep 07-11, 1994). In: Nucleosides and Nucleotides, Vol. 14, no. 3-5, p. 867-870 (1995) |
Permanent URL |
http://hdl.handle.net/2078.1/63116 |