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Paired Helical Filaments in Spinal Ganglion Neurons of Elderly Rats

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van den Bosch Sanchez de Aguilar, Philippe [UCL] Goemaere-Vanneste, J. [UCL]

(eng) Ultrastructural study of spinal ganglion neurons in elderly rats (aged from 24 to 32 months) allowed the observation of spontaneously occurring paired helical filaments (PHFs). On the basis of this finding the rat may provide an animal model for the study of the morphogenesis and nature of the PHFs which are characteristic of human senile dementia of the Alzheimer type.

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès restreint
Publication date 1984
Language Anglais
Journal information "Virchows Archiv. Section B: Cell Pathology" - Vol. 47, no. 3, p. 217-222 (1984)
Peer reviewed yes
Publisher Springer Verlag (New York)
issn 0340-6075
e-issn 0340-6075
Publication status Publié
Affiliation UCL - MD/BICL - Département de biochimie et de biologie cellulaire
Links
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Bibliographic reference van den Bosch Sanchez de Aguilar, Philippe ; Goemaere-Vanneste, J.. Paired Helical Filaments in Spinal Ganglion Neurons of Elderly Rats. In: Virchows Archiv. Section B: Cell Pathology, Vol. 47, no. 3, p. 217-222 (1984)
Permanent URL http://hdl.handle.net/2078.1/55311