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A Rare Case of Bronchial Stenosis in Wegeners Granulomatosis - Dramatic Response To Intravenous Cyclophosphamide and Oral Cotrimoxazole

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Hirsch, MM. Collard, Philippe [UCL] Houssiau, Frédéric [UCL] Devogelaer, Jean-Pierre [UCL] Dedeuxchaisnes, CN.

We describe a patient with Wegener's granulomatosis (WG) who developed as the only pulmonary manifestation a severe proximal bronchial stenosis despite conventional treatment with steroids and oral cyclophosphamide. The patient subsequently responded to a combined therapy with intravenous (IV) cyclophosphamide and oral cotrimoxazole. We stress the rarity of bronchial involvement in WG and discuss the role of IV cyclophosphamide and cotrimoxazole in the management of this disease.

Document type Article de périodique (Journal article) – Article de recherche
Publication date 1992
Language Anglais
Journal information "Journal of Rheumatology" - Vol. 19, no. 5, p. 821-824 (1992)
Peer reviewed yes
Publisher J Rheumatol Publ Co (Toronto)
issn 0315-162X
e-issn 1499-2752
Publication status Publié
Affiliations UCL - Cliniques universitaires Saint-Luc
UCL
Keywords WEGENERS GRANULOMATOSIS ; BRONCHIAL STENOSIS ; CYCLOPHOSPHAMIDE ; COTRIMOXAZOLE
Links
Bibliographic reference Hirsch, MM. ; Collard, Philippe ; Houssiau, Frédéric ; Devogelaer, Jean-Pierre ; Dedeuxchaisnes, CN.. A Rare Case of Bronchial Stenosis in Wegeners Granulomatosis - Dramatic Response To Intravenous Cyclophosphamide and Oral Cotrimoxazole. In: Journal of Rheumatology, Vol. 19, no. 5, p. 821-824 (1992)
Permanent URL http://hdl.handle.net/2078.1/50398