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A case of long-lasting but reversible isolated amnesia of unknown aetiology

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Ivanoiu, Adrian [UCL] Aubert, Geneviève [UCL] Duprez, Thierry [UCL] Coyette, F. Seron, Xavier [UCL] Sindic, Christian [UCL] Laterre, Emile-Christian [UCL]

We report the case of a 64-year-old man with an acute isolated and prolonged transient amnesic state, The underlying aetiology remained obscure, Brain magnetic resonance examination demonstrated only non-specific slight and transitory signal intensity abnormalities within the left hippocampus on TP-weighted images, Electroencephalographic studies showed repetitive periodical and prolonged bursts of rhythmic theta activity, originating from the left fronto-temporal region, but no typical epileptiform discharges, As an epileptic origin could not be excluded, anti-epileptic treatment was administered. Subsequently, electroencephalographic abnormalities disappeared completely after a few days, On follow-up, repetitive clinical and neuropsychological comprehensive evaluations showed that the mnesic capacities improved slowly and gradually. The gradual improvement concerned time and place orientation first of all and was followed thereafter by improvement of explicit memory and the capacity to learn new information. Clinically, at this stage, the patient appeared appropriately orientated, according to the medical staff and his family, although memory tests remained abnormal. The memory deficit lasted similar to 3 months but was followed by complete recovery. In our discussion, we consider possible aetiologies for transient amnesia with emphasis on an epileptic as opposed to a vascular aetiology by focal hippocampal ischaemia.

Document type Article de périodique (Journal article) – Article de recherche
Publication date 1998
Language Anglais
Journal information "Neurocase" - Vol. 4, no. 3, p. 231-243 (1998)
Peer reviewed yes
Publisher Oxford Univ Press (Oxford)
issn 1355-4794
e-issn 1465-3656
Publication status Publié
Affiliations UCL - MD/NOPS - Département de neurologie et de psychiatrie
UCL - (SLuc) Service de neurologie
UCL - (SLuc) Service de radiologie
UCL - MD/RAIM - Département de radiologie et d'imagerie médicale
Keywords memory ; neuropsychology ; transient global amnesia ; cerebral ischaemia ; transient ischaemic attack ; epilepsy
Links
  1. Adams R D, Principles of neurology, 371 (1993)
  2. Ahem G L, Neurology, 44, 1270 (1994)
  3. Baddeley A, The doors and people test (1994)
  4. Bogousslavsky Julien, Regli Franco, Transient Global Amnesia and Stroke, 10.1159/000116240
  5. Buschke H, Neurology, 24, 1019 (1974)
  6. Cardebat D, Acta Neurologica Belgka, 90, 207 (1990)
  7. Chalmers J., Risk M. T. A., Kean D. M., Grant R., Ashworth B., Campbell I. W., Severe Amnesia After Hypoglycemia: Clinical, Psychometric, and Magnetic Resonance Imaging Correlations, 10.2337/diacare.14.10.922
  8. DE RENZI E., VIGNOLO L. A., THE TOKEN TEST: A SENSITIVE TEST TO DETECT RECEPTIVE DISTURBANCES IN APHASICS, 10.1093/brain/85.4.665
  9. Deisenhammer E., Transient global amnesia as an epileptic manifestation, 10.1007/bf00313302
  10. Deweer B, Cortex, 30, 113 (1994)
  11. Duyckaerts C., Derouesne C., Signoret J. L., Gray F., Escourolle R., Castaigne P., Bilateral and limited amygdalohippocampal lesions causing a pure amnesic syndrome, 10.1002/ana.410180307
  12. Ergis, A M. 1994.Memoire implicite dans la maladie ďAlzheimer débutante, amorçage perceptif et conceptuel, Doctorat de ľUniversité 6Paris unpublished data
  13. Fisher C M, Acta Neurologica Scandinavica, 40, 7 (1964)
  14. Gallassi R, Epilepsia, 33, S21 (1992)
  15. Gallassi R., Stracciari A., Morreale A., Lorusso S., Rebucci G.G., Lugaresi E., Transient Global Amnesia: Neuropsychological Findings after Single and Multiple Attacks, 10.1159/000116957
  16. Ghika J, Transient global amnesia and related disorders, 66 (1990)
  17. Halgren E, Advances in neurology, 55, 385 (1991)
  18. High Walter M., Levin Harvey S., Gary Howard E., Recovery of orientation following closed-head injury, 10.1080/01688639008401013
  19. Hodges, J R. 1991.Transient amnesia–clinical and neuropsychological aspects. Major problems in neurology, vol. 24, 138–43. Philadelphia: WB Saunders.
  20. Hogrefe C J, Test d2 (1962)
  21. Jernigan T L, Localisation and neuroimaging in neuropsychology, 599 (1994)
  22. Kapur N, Transient epileptic amnesia--a clinical update and a reformulation., 10.1136/jnnp.56.11.1184
  23. Kapur, N. 1994.Memory disorders in clinical practice, 182–93. Hillsdale, NJ: Lawrence Erlbaum.
  24. Kartsounis L D, Rudge P, Stevens J M, Bilateral lesions of CA1 and CA2 fields of the hippocampus are sufficient to cause a severe amnesic syndrome in humans., 10.1136/jnnp.59.1.95
  25. KIMURA Seigo, KUMANO Takanori, MIYAO Shin''ichi, TERAMOTO Jun, Herpes Simplex Encephalitis with Transient Global Amnesia as an Early Sign., 10.2169/internalmedicine.34.131
  26. Kopelman M D, Autobiographical memory interview (1989)
  27. Kopelman M D, Panayiotopoulos C P, Lewis P, Transient epileptic amnesia differentiated from psychogenic "fugue": neuropsychological, EEG, and PET findings., 10.1136/jnnp.57.8.1002
  28. Kritchevsky M, Neurology, 43, 326 (1993)
  29. Lee B. I., Lee B. C., Hwang Y. M., Sohn Y. H., Jung J. W., Park S. C., Han M. H., Prolonged Ictal Amnesia with Transient Focal Abnormalities on Magnetic Resonance Imaging, 10.1111/j.1528-1157.1992.tb01756.x
  30. MAZZUCCHI A., MORETTI G., CAFFARRA P., PARMA M., NEUROPSYCHOLOGICAL FUNCTIONS IN THE FOLLOW-UP OF TRANSIENT GLOBAL AMNESIA, 10.1093/brain/103.1.161
  31. Miller J W, Neurology, 37, 733 (1987)
  32. Miller J W, Archives of Neurology, 44, 629 (1987)
  33. Milner B, British Medical Bulletin, 27, 272 (1971)
  34. Morris Robin G., Short-term forgetting in senile dementia of the Alzheimer's type, 10.1080/02643298608252670
  35. Naquet R, Revue Neurologique (Paris), 105, 203 (1961)
  36. Nehemkis Alexis M., Lewinsohn Peter M., Effects of Left and Right Cerebral Lesions on the Naming Process, 10.2466/pms.1972.35.3.787
  37. Hippocampal amnesia, 10.1080/13554799608402404
  38. Ott B. R., Saver J. L., Unilateral amnesic stroke. Six new cases and a review of the literature, 10.1161/01.str.24.7.1033
  39. PALMINI ANDRÉ L., GLOOR PIERRE, JONES-GOTMAN MARILYN, PURE AMNESTIC SEIZURES IN TEMPORAL LOBE EPILEPSY: DEFINITION, CLINICAL SYMPTOMATOLOGY AND FUNCTIONAL ANATOMICAL CONSIDERATIONS, 10.1093/brain/115.3.749
  40. Pramming S, Thorsteinsson B, Theilgaard A, Pinner E M, Binder C, Cognitive function during hypoglycaemia in type I diabetes mellitus., 10.1136/bmj.292.6521.647
  41. Pritchard P B, Neurology, 35, 1188 (1985)
  42. Raven J C, Guide to the standard progressive matrices (1960)
  43. Rey A, Test de copie ďune figure complexe (1959)
  44. Rowan A J, Neurology, 29, 869 (1979)
  45. Stracciari Andrea, Ciucci Gabriele, Bianchedi Giovanni, Rebucci Giuseppe, Epileptic Transient Amnesia, 10.1159/000117339
  46. Takahashi S., Higano S., Kurihara N., Mugikura S., Sakamoto K., Nomura H., Ikeda H., Correlation of lesions in the hippocampal region noted on MR images with clinical features, 10.1007/s003300050151
  47. Tanabe H., Hashikawa K., Nakagawa Y., Ikeda M., Yamamoto H., Harada K., Tsumoto T., Nishimura T., Shiraishi J., Kimura K., Memory loss due to transient hypoperfusion in the medial temporal lobes including hippocampus, 10.1111/j.1600-0404.1991.tb04897.x
  48. Tassinari Carlo Alberto, Ciarmatori Claudio, Alesi Carlo, Cardinaletti Lina, Salvi Fabrizio, Rubboli Guido, Plasmati Rosaria, Forti Alberto, Michelucci Roberto, Transient Global Amnesia as a Postictal State from Recurrent Partial Seizures, 10.1111/j.1528-1157.1991.tb05545.x
  49. Tien R D, Radiology, 194, 249 (1995)
  50. Vuilleumier P., Despland P. A., Regli F., Failure to recall (but not to remember): Pure transient amnesia during nonconvulsive status epilepticus, 10.1212/wnl.46.4.1036
  51. Walsh G O, Neurologic clinics, vol. 11, number 4. Epilepsy I: diagnosis and treatment, 835 (1993)
  52. Wechsler D, Echelle clinique de mémoire de Wechsler révisée (1991)
  53. Westmoreland Barbara F, Klass Donald W, A distinctive rhythmic EEG discharge of adults, 10.1016/0013-4694(81)90008-0
  54. Zeman A ZJ, Journal of Neurology Neurosurgery and Psychiatry (1998)
  55. Morgan Zola S, Journal of Neuroscience, 6, 2950 (1986)
  56. Zorzon M., Antonutti L., Mase G., Biasutti E., Vitrani B., Cazzato G., Transient Global Amnesia and Transient Ischemic Attack : Natural History, Vascular Risk Factors, and Associated Conditions, 10.1161/01.str.26.9.1536
Bibliographic reference Ivanoiu, Adrian ; Aubert, Geneviève ; Duprez, Thierry ; Coyette, F. ; Seron, Xavier ; et. al. A case of long-lasting but reversible isolated amnesia of unknown aetiology. In: Neurocase, Vol. 4, no. 3, p. 231-243 (1998)
Permanent URL http://hdl.handle.net/2078.1/45108