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Photochemical rearrangement of oxaziridines and nitrones in the hexahydroindole series: A convenient synthetic route to 1-azabicyclo[5.2.0]nonan-2-ones as novel RGD mimetics

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Bourguet, E Declercq, Jean-Paul [UCL] Baneres, JL Girard, JP. Parello, J. Lusinchi, X

GRAPHICS Photolysis of oxaziridines a or nitrones b provides a convenient synthetic route to fused bicyclic lactams c adequately substituted on both cycles A and B as scaffolds for mimicking conformationally constrained beta -turn peptides as in the tripeptide RGD signaling motif of fibronectin.

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès restreint
Publication date 2001
Language Anglais
Journal information "Organic Letters" - Vol. 3, no. 20, p. 3067-3070 (2001)
Peer reviewed yes
Publisher Amer Chemical Soc (Washington)
issn 1523-7060
e-issn 1523-7052
Publication status Publié
Affiliation UCL - SC/CHIM - Département de chimie
Links
Bibliographic reference Bourguet, E ; Declercq, Jean-Paul ; Baneres, JL ; Girard, JP. ; Parello, J. ; et. al. Photochemical rearrangement of oxaziridines and nitrones in the hexahydroindole series: A convenient synthetic route to 1-azabicyclo[5.2.0]nonan-2-ones as novel RGD mimetics. In: Organic Letters, Vol. 3, no. 20, p. 3067-3070 (2001)
Permanent URL http://hdl.handle.net/2078.1/42481