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Yersinia type III secretion: send in the effectors

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Cornelis, Guy

Pathogenic Yersinia spp (Yersinia pestis, Yersinia pseudotuberculosis, and Yersinia enterocolitica) have evolved an exquisite method for delivering powerful effectors into cells of the host immune system where they inhibit signaling cascades and block the cells' response to infection. Understanding the molecular mechanisms of this system has provided insight into the processes of phagocytosis and inflammation.

Document type Article de périodique (Journal article) – Synthèse de littérature
Access type Accès restreint
Publication date 2002
Language Anglais
Journal information "The Journal of Cell Biology" - Vol. 158, no. 3, p. 401-408 (2002)
Peer reviewed yes
Publisher Rockefeller Univ Press (New York)
issn 0021-9525
e-issn 1540-8140
Publication status Publié
Affiliation UCL
Keywords bacterial pathogenesis ; Yersinia ; Yops ; translocation ; type III secretion
Links
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Bibliographic reference Cornelis, Guy. Yersinia type III secretion: send in the effectors. In: The Journal of Cell Biology, Vol. 158, no. 3, p. 401-408 (2002)
Permanent URL http://hdl.handle.net/2078.1/41753