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Theoretical approach to the destruction or sterilization of drugs in aqueous solution

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Slegers, Catherine [UCL] Tilquin, Bernard [UCL]

Two novel applications in the radiation processing of aqueous solutions of drugs are the sterilization of injectable drugs and the decontamination of hospital wastewaters by ionizing radiation. The parameters influencing the destruction of the drug in aqueous solutions are studied with a computer simulation program. This theoretical approach has revealed that the dose rate is the most important parameter that can be easily varied in order to optimize the destruction or the protection of the drug. (C) 2004 Elsevier Ltd. All rights reserved.

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès restreint
Publication date 2005
Language Anglais
Journal information "Radiation Physics and Chemistry" - Vol. 72, no. 2-3, p. 363-365 (2005)
Peer reviewed yes
Publisher Pergamon-elsevier Science Ltd (Oxford)
issn 0969-806X
e-issn 1879-0895
Publication status Publié
Affiliation UCL - MD/FARM - Ecole de pharmacie
Keywords radiation processing ; radiosterilization decontamination drugs ; wastewater ; computer simulation
Links
Bibliographic reference Slegers, Catherine ; Tilquin, Bernard. Theoretical approach to the destruction or sterilization of drugs in aqueous solution. In: Radiation Physics and Chemistry, Vol. 72, no. 2-3, p. 363-365 (2005)
Permanent URL http://hdl.handle.net/2078.1/39647