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Effects of fructosamine-3-kinase deficiency on function and survival of mouse pancreatic islets after prolonged culture in high glucose or ribose concentrations
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Document type | Article de périodique (Journal article) – Article de recherche – Comparative Study, Journal Article, Research Support, Non-U.S. Gov't |
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Access type | Accès libre |
Publication date | 2010 |
Language | Anglais |
Journal information | "American Journal of Physiology: Endocrinology and Metabolism" - Vol. 298, no. 3, p. E586-E596 (2010) |
Peer reviewed | yes |
Publisher | American Physiological Society ((United States) Bethesda, MD) |
issn | 0193-1849 |
e-issn | 1522-1555 |
Publication status | Publié |
Affiliations |
UCL
- SSS/DDUV - Institut de Duve UCL - SSS/IREC - Institut de recherche expérimentale et clinique UCL - SSS/IREC/EDIN - Pôle d'endocrinologie, diabète et nutrition |
MESH Subject | Time Factors ; Ribose - pharmacokinetics ; Phosphotransferases (Alcohol Group Acceptor) - deficiency - metabolism ; Organ Culture Techniques ; Mice, Knockout ; Mice ; Male ; Islets of Langerhans - cytology - metabolism ; Glucose - pharmacokinetics ; Female ; Cell Survival - physiology ; Animals |
Keywords | apoptosis ; cytosolic calcium concentration ; diabetes ; glucotoxicity ; glycation ; insulin secretion ; oxidative stress ; pancreatic beta-cell ; intracellular fructosamines |
Links |
Bibliographic reference | Pascal, Séverine ; Veiga da Cunha, Maria ; Gilon, Patrick ; Van Schaftingen, Emile ; Jonas, Jean-Christophe. Effects of fructosamine-3-kinase deficiency on function and survival of mouse pancreatic islets after prolonged culture in high glucose or ribose concentrations. In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 298, no. 3, p. E586-E596 (2010) |
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Permanent URL | http://hdl.handle.net/2078.1/34157 |