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Results from eqas for antibiotics show the need to improve the quality of the pharmacokinetic interpretation during monitoring

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Van de Walle, P. Delattre, Isabelle [UCL] Devleeschouwer, N. Van Campenhout, C. Wallemacq, Pierre [UCL]

(eng) A mandatory external quality assessment scheme for Therapeutic Drug Monitoring is operational in Belgium. This quality scheme aims to provide an assessment of the state of the art of Therapeutic Drug Monitoring as practiced in the Belgian laboratories. The external quality assessment scheme' main objective is to evaluate laboratories on their ability to approach their peer group's median value. In addition to the analytical result, an interpretation for some parameters such as aminoglycosides is frequently asked by using case reports. Even when analytical performance is good, many laboratories encounter problems interpreting the results especially when the intervals of blood collections are uncommon. Results illustrate the added value of the use of dedicated software to support pharmacokinetic interpretation.

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès restreint
Publication date 2010
Language Anglais
Journal information "Acta Clinica Belgica (Multilingual Edition)" - Vol. 65, no. Suppl. 1, p. 2-6 (2010)
Peer reviewed yes
Publisher Acta Clinica Belgica (Bruxelles)
issn 0001-5512
Affiliations UCL - SSS/IREC - Institut de recherche expérimentale et clinique
UCL - SSS/IREC/LTAP - Louvain Centre for Toxicology and Applied Pharmacology
UCL - SSS/LDRI - Louvain Drug Research Institute
UCL - (SLuc) Service de biochimie médicale
Keywords antibiotics ; program ; pharmacokinetic ; EQAS
Links
Bibliographic reference Van de Walle, P. ; Delattre, Isabelle ; Devleeschouwer, N. ; Van Campenhout, C. ; Wallemacq, Pierre. Results from eqas for antibiotics show the need to improve the quality of the pharmacokinetic interpretation during monitoring. In: Acta Clinica Belgica (Multilingual Edition), Vol. 65, no. Suppl. 1, p. 2-6 (2010)
Permanent URL http://hdl.handle.net/2078.1/33938