Yewhalaw, Delenasaw
Van Bortel, Wim
Denis, Leen
Coosemans, Marc
Duchateau, Luc
Speybroeck, Niko
[UCL]
The status of knockdown resistance (kdr) mutation was investigated in the major malaria vector Anopheles arabiensis Patton (Diptera: Culicidae) from Ethiopia. Among 240 mosquito samples from 15 villages of southwestern Ethiopia that were screened by allele-specific polymerase chain reaction for kdr mutations, the West African kdr mutation (L1014F) was detected in almost all specimens (98.5%), whereas the East African kdr mutation (L1014S) was absent. Moreover, the mortality of An. gambiae s.l. to diagnostic dosages of 4% DDT, 0.75% permethrin, and 0.05% deltamethrin from bioassay results was 1.0%, 18.1%, and 82.2%, respectively. We report here the highest kdr allele frequency ever observed in An. arabiensis and its implications in malaria vector control in Ethiopia are discussed.
Bibliographic reference |
Yewhalaw, Delenasaw ; Van Bortel, Wim ; Denis, Leen ; Coosemans, Marc ; Duchateau, Luc ; et. al. First evidence of high knockdown resistance frequency in Anopheles arabiensis (Diptera: Culicidae) from Ethiopia. In: American Journal of Tropical Medicine and Hygiene, Vol. 83, no. 1, p. 122-125 (2010) |
Permanent URL |
http://hdl.handle.net/2078.1/32808 |