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EANM procedure guideline for brain perfusion SPECT using (99m)Tc-labelled radiopharmaceuticals : version 2

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Kapucu, Özlem L. Nobili, Flavio Varrone, Andrea Booij, Jan Vander Borght, Thierry [UCL] Van Laere, Koen J. [KUL]

These guidelines summarize the current views of the European Association of Nuclear Medicine Neuroimaging Committee (ENC). The purpose of the guidelines is to assist nuclear medicine practitioners when making recommendations, performing, interpreting, and reporting the results of brain perfusion single photon emission computed tomography (SPECT) studies using (99m)Tc-labelled radiopharmaceuticals. The aim is to achieve a high quality standard for brain perfusion SPECT imaging, which will increase the diagnostic impact of this technique in clinical practice. The present document replaces a former version of the guideline published in 2001 which was inspired by the Society of Nuclear Medicine Procedure Guideline for Brain Perfusion SPECT [1], the views of the Society of Nuclear Medicine Brain Imaging Council [2], and the individual experience of experts in European countries. The guidelines are intended to present information specifically adapted to European practice. The information provided should be taken in the context of local conditions and regulations.

Document type Article de périodique (Journal article) – Article de recherche – Journal Article
Access type Accès restreint
Publication date 2009
Language Anglais
Journal information "European Journal of Nuclear Medicine and Molecular Imaging" - Vol. 36, no. 12, p. 2093-2102 (2009)
Peer reviewed yes
Publisher Springer ((Germany) Heidelberg)
issn 1619-7070
e-issn 1619-7089
Publication status Publié
Affiliation UCL - (MGD) Service de médecine nucléaire
MESH Subject Tomography, Emission-Computed, Single-Photon - adverse effects - contraindications - instrumentation - methods ; Societies ; Research Report ; Radiopharmaceuticals - adverse effects - contraindications - diagnostic use ; Pregnancy ; Perfusion Imaging - adverse effects - contraindications - instrumentation - methods ; Patient Care Management ; Organotechnetium Compounds - diagnostic use ; Nuclear Medicine - instrumentation - methods ; Image Interpretation, Computer-Assisted ; Humans ; Female ; Europe ; Child ; Brain - radionuclide imaging ; Adult
Keywords brain ; Perfusion ; SPECT ; HMPAO ; ECD ; Epilepsy ; Dementia
Links
  1. Juni JE, Waxman AD, Devous MD Sr, Tikofsky RS, Ichise M, Van Heertum RL, et al. Society of Nuclear Medicine procedure guideline for brain perfusion single photon computed tomography (SPECT) using Tc-99 m radiopharmaceuticals. Procedure Guidelines Manual June 2002. Reston, VA: Society of Nuclear Medicine; 2002. p. 113–118.
  2. Society of Nuclear Medicine Brain Imaging Council. Ethical clinical practice of functional brain imaging. J Nucl Med 1996;37:1256–59.
  3. Reba RC, Holman BL. Brain perfusion radiotracers. In: Diksic M, Reba RC, editors. Radiopharmaceuticals and brain pathology studied with PET and SPECT. Boca Raton: CRC Press; 1990.
  4. Inoue K, Nakagawa M, Goto R, Kinomura S, Sato T, Sato K, et al. Regional differences between 99mTc-ECD and 99mTc-HMPAO SPECT in perfusion changes with age and gender in healthy adults. Eur J Nucl Med Mol Imaging 2003;30:1489–97.
  5. Friedman NC, Burt RW. Cerebral perfusion imaging. In: Henkin RE, Bova D, Dillehay L, Karesh SM, Halama JR, Wagner RH, editors. Nuclear medicine. 2nd ed. Philadelphia: Mosby-Elsevier; 2006. p. 1255–81.
  6. Latchaw RE, Yonas H, Hunter GJ, Yuh WT, Ueda T, Sorensen AG, et al. Guidelines and recommendations for perfusion imaging in cerebral ischemia: a scientific statement for healthcare professionals by the writing group on perfusion imaging, from the Council on Cardiovascular Radiology of the American Heart Association. Stroke 2003;34:1084–104.
  7. Masdeu JC, Irimia P, Asenbaum S, Bogousslavsky J, Brainin M, Chabriat H, et al. EFNS guideline on neuroimaging in acute stroke. Report of an EFNS task force. Eur J Neurol 2006;13:1271–83.
  8. Mountz JM, Liu HG, Deutsch G. Neuroimaging in cerebrovascular disorders: measurement of cerebral physiology after stroke and assessment of stroke recovery. Semin Nucl Med 2003;33:56–76.
  9. Aso K, Ogasawara K, Sasaki M, Kobayashi M, Suga Y, Chida K, et al. Preoperative cerebrovascular reactivity to acetazolamide measured by brain perfusion SPECT predicts development of cerebral ischemic lesions caused by microemboli during carotid endarterectomy. Eur J Nucl Med Mol Imaging 2009;26:294–301.
  10. Lee TH, Kim SJ, Kim IJ, Kim YK, Kim DS, Park KP. Statistical parametric mapping and statistical probabilistic anatomical mapping analyses of basal/acetazolamide Tc-99m ECD brain SPECT for efficacy assessment of endovascular stent placement for middle cerebral artery stenosis. Neuroradiology 2007;49:289–98.
  11. Lee HY, Paeng JC, Lee DS, Lee JS, Oh CW, Cho MJ, et al. Efficacy assessment of cerebral arterial bypass surgery using statistical parametric mapping and probabilistic brain atlas on basal/acetazolamide brain perfusion SPECT. J Nucl Med 2004;45:202–6.
  12. Sugawara Y, Kikuchi T, Ueda T, Sugawara Y, Kikuchi T, Ueda T, et al. Usefulness of brain SPECT to evaluate brain tolerance and hemodynamic changes during temporary balloon occlusion test and after permanent carotid occlusion. J Nucl Med 2002;43(12):1616–23.
  13. Goffin K, Dedeurwaerdere S, Van Laere K, Van Paesschen W. Neuronuclear assessment of patients with epilepsy. Semin Nucl Med 2008;38:227–39.
  14. Van Paesschen W, Dupont P, Sunaert S, Goffin K, Van Laere K. The use of SPECT and PET in routine clinical practice in epilepsy. Curr Opin Neurol 2007;20:194–202.
  15. Van Paesschen W. Ictal SPECT. Epilepsia 2004;45(Suppl 4):35–40.
  16. Zaknun JJ, Bal C, Maes A, Tepmongkol S, Vazquez S, Dupont P, et al. Comparative analysis of MR imaging, Ictal SPECT and EEG in temporal lobe epilepsy: a prospective IAEA multi-center study. Eur J Nucl Med Mol Imaging 2008;35:107–15.
  17. Patil S, Biassoni L, Borgwardt L. Nuclear medicine in pediatric neurology and neurosurgery: epilepsy and brain tumors. Semin Nucl Med 2007;37:357–81.
  18. Devous MD Sr. Functional brain imaging in the dementias: role in early detection, differential diagnosis, and longitudinal studies. Eur J Nucl Med Mol Imaging 2002;29:1685–96.
  19. Matsuda H. Role of neuroimaging in Alzheimer's disease, with emphasis on brain perfusion SPECT. J Nucl Med 2007;48:1289–300.
  20. Kemp PM, Holmes C. Imaging in dementia with Lewy bodies: a review. Nucl Med Commun 2007;28:511–9.
  21. Chang W. N., Lu C. H., Huang C. R., Chuang Y. C., Tsai N. W., Chen S. F., Chang C. C., Wang H. C., Cerebrospinal fluid 14-3-3-γ protein level in eight HIV-negative cryptococcal meningitis adults, 10.1111/j.1468-1331.2008.02091.x
  22. Kato H, Yoshikawa T, Oku N, Imaizumi M, Takasawa M, Kimura Y, et al. Statistical parametric analysis of cerebral blood flow in vascular dementia with small-vessel disease using Tc-HMPAO SPECT. Cerebrovasc Dis 2008;26:556–62.
  23. Le Ber I, Guedj E, Gabelle A, Verpillat P, Volteau M, Thomas-Anterion C, et al. Demographic, neurological and behavioural characteristics and brain perfusion SPECT in frontal variant of frontotemporal dementia. Brain 2006;129:3051–65.
  24. Johnson KA, Moran EK, Becker JA, Blacker D, Fischman AJ, Albert MS. Single photon emission computed tomography perfusion differences in mild cognitive impairment. J Neurol Neurosurg Psychiatry 2007;78:240–7.
  25. Newberg AB, Alavi A. Neuroimaging in patients with head injury. Semin Nucl Med 2003;33:136–47.
  26. Yacubian Elza M. T., Marie Sueli K. N., Valério Rosa M. F., Jorge Carmen L., Yamaga Liliam, Buchpiguel Carlos A., Neuroimaging Findings in Rasmussen's Syndrome, 10.1111/jon19977116
  27. Launes J., Siren J., Valanne L., Salonen O., Nikkinen P., Seppalainen A. -M., Liewendahl K., Unilateral hyperperfusion in brain-perfusion SPECT predicts poor prognosis in acute encenhalitis, 10.1212/wnl.48.5.1347
  28. Kao CH, Chan JL, ChangLai SP, Liao KK, Chieng PU. The role of FDG-PET, HMPAO SPECT and MRI in the detection of brain involvement in patients with systemic lupus erythematosus. Eur J Nucl Med 1999;26:129–34.
  29. Vignola S, Nobili F, Picco P, Gattorno M, Buoncompagni A, Vitali P, et al. Brain perfusion SPECT in juvenile neuro-Behçet's disease. J Nucl Med 2001;42:1151–7.
  30. Tucker KA, Robertson KR, Lin W, Smith JK, An H, Chen Y, et al. Neuroimaging in human immunodeficiency virus infection. J Neuroimmunol 2004;157:153–62.
  31. Donohoe KJ, Frey KA, Gerbaudo VH, Mariani G, Nagel JS, Shulkin B. Procedure guideline for brain death scintigraphy. J Nucl Med 2003;44:846–51.
  32. Smith DJ, Cavanagh JT. The use of single photon emission computed tomography in depressive disorders. Nucl Med Commun 2005;26:197–203.
  33. Thomsen G, de Nijs R, Hogh-Rasmussen E, Frokjaer V, Svarer C, Knudsen GM. Required time delay from Tc-99 m HMPAO injection to SPECT data acquisition: healthy subjects and patients with rCBF pattern. Eur J Nucl Med Mol Imaging 2009;35:2212–9.
  34. Bartenstein P, Minoshima S, Hirsch C, Buch K, Willoch F, Mösch D, et al. Quantitative assessment of cerebral blood flow in patients with Alzheimer's disease by SPECT. J Nucl Med 1997;38:1095–101.
  35. Friston KJ. Introduction: experimental design and statistical parametric mapping. In: Frackowiak RSJ, Friston KJ, Frith C, editors. Human brain function. 2nd ed. New York: Academic Press; 2003.
  36. McNally KA, Paige AL, Varghese G, Zhang H, Novotny EJ Jr, Spencer SS, et al. Localizing value of ictal-interictal SPECT analyzed by SPM (ISAS). Epilepsia 2005;46:1450–64.
  37. Kaiboriboon K, Lowe VJ, Chantarujikapong SI, Hogan RE. The usefulness of subtraction ictal SPECT coregistered to MRI in single- and dual-headed SPECT cameras in partial epilepsy. Epilepsia 2002;43:408–14.
  38. Dupont P, Van Paesschen W, Palmini A, Ambayi R, Van Loon J, Goffin J, et al. Ictal perfusion patterns associated with single MRI-visible focal dysplastic lesions: implications for the noninvasive delineation of the epileptogenic zone. Epilepsia 2006;47:1550–7.
  39. Seo Y, Mari C, Hasegawa BH. Technological development and advances in single-photon emission computed tomography/computed tomography. Semin Nucl Med 2008;38:177–98.
  40. Grova C, Jannin P, Biraben A, Buvat I, Benali H, Bernard AM, et al. A methodology for generating normal and pathological brain perfusion SPECT images for evaluation of MRI/SPECT fusion methods: application in epilepsy. Phys Med Biol 2003;48:4023–43.
Bibliographic reference Kapucu, Özlem L. ; Nobili, Flavio ; Varrone, Andrea ; Booij, Jan ; Vander Borght, Thierry ; et. al. EANM procedure guideline for brain perfusion SPECT using (99m)Tc-labelled radiopharmaceuticals : version 2. In: European Journal of Nuclear Medicine and Molecular Imaging, Vol. 36, no. 12, p. 2093-2102 (2009)
Permanent URL http://hdl.handle.net/2078.1/29645