Bosly, André
[UCL]
Haioun, C.
Gisselbrecht, C.
Reyes, F.
Coiffier, B.
Autologous stem-cell transplantation (ASCT) has permitted to deliver high-dose therapy (HDT). In aggressive lymphomas, the GELA group conducted prospective and retrospective studies comparing HDT + ASCT to conventional sequential chemotherapy. In relapsing patients and in partial remission, retrospective studies showed a survival advantage for HDT + ASCT over sequential chemotherapy. In complete response, advantage for HDT + ASCT was demonstrated in a prospective trial only for patients with high intermediate or high risk in the IPI score. The attainment of a maximal reduction of the tumoral mass before going HDT is very important either in first line or in relapsing patients.
Bibliographic reference |
Bosly, André ; Haioun, C. ; Gisselbrecht, C. ; Reyes, F. ; Coiffier, B.. High-dose treatment with autologous stem cell transplantation versus sequential chemotherapy: the GELA experience.. In: European journal of haematology. Supplementum, Vol. 64, p. 3-7 (2001) |
Permanent URL |
http://hdl.handle.net/2078.1/27486 |