User menu

Accès à distance ? S'identifier sur le proxy UCLouvain

The proximo-distal carcinogen N-hydroxy-2-fluorenylacetamide, toxification and detoxification routes due to electrophilic and combined nucleophilic and electrophilic tautomerism effects.

Primary tabs

Lhoëst, Georges [UCL] Roberfroid, Marcel [UCL] Mercier, Michel [UCL]
Document type Article de périodique (Journal article) – Journal Article
Publication date 1978
Journal information "Biomedical mass spectrometry" - Vol. 5, no. 1, p. 38-43 (1978)
issn 0306-042X
Publication status Publié
Affiliation UCL
MESH Subject Alkaloids ; Chemical Phenomena ; Chemistry ; Fluorenes - toxicity ; Hydroxyacetylaminofluorene - toxicity ; Mass Spectrometry ; Metabolic Detoxication, Drug ; Molecular Conformation ; Structure-Activity Relationship
Links
  1. Miller, Cancer Res., 21, 815 (1961)
  2. Boudène, Ann. Biol. Clin. (Paris), 34, 1 (1976)
  3. Miller, Cancer Res., 30, 559 (1970)
  4. Cramer, J. Biol. Chem., 235, 885 (1960)
  5. Lhoëst, Biomed. Mass Spectrom., 3, 21 (1976)
  6. Laar Conrad, Ueber die Hypothese der wechselnden Bindung, 10.1002/cber.188601901165
  7. Escale, Tetrahedron, 32, 1369 (1976)
  8. Wheeler, J. Org. Chem., 22, 547 (1957)
  9. Lhoest G., De Neys R., Defay N., Seibl J., Pecher J., Martin R. H., Alcaloides Indoliques. VII. Structure de la Voacoline, 10.1002/bscb.19650741106
  10. Weisburger, Pharmacol. Rev., 25, 1 (1973)
  11. Kriek, Biochim. Biopys. Acta, 355, 177 (1974)
  12. Miller James A., Miller Elizabeth C., The Metabolic Activation of Carcinogenic Aromatic Amines and Amides1, Carcinogenesis and Carcinogen Testing ISBN:9783805511100 p.273-301, 10.1159/000391399
  13. Sekely, J. Natl Cancer Inst., 50, 1337 (1973)
  14. and Anal. Biochem. in press.
  15. Irving, Biochemistry, 9, 2471 (1970)
  16. Braude, Nature, 169, 80 (1952)
  17. Gutman, J. Biol. Chem., 247, 660 (1971)
Bibliographic reference Lhoëst, Georges ; Roberfroid, Marcel ; Mercier, Michel. The proximo-distal carcinogen N-hydroxy-2-fluorenylacetamide, toxification and detoxification routes due to electrophilic and combined nucleophilic and electrophilic tautomerism effects.. In: Biomedical mass spectrometry, Vol. 5, no. 1, p. 38-43 (1978)
Permanent URL http://hdl.handle.net/2078.1/25166