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HPLC analysis of diuron and metabolites in blood and urine.

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Van Boven, Michel [UCL] Laruelle, L. Daenens, P.

A high-pressure liquid chromatographic method for the determination of diuron and its metabolites in human urine and blood is presented. The synthesis of different metabolites and of a suitable internal standard is described and the structure of the compounds is determined by mass spectrometry and nuclear magnetic resonance spectroscopy. The method is applied to an overdose case.

Document type Article de périodique (Journal article) – Case Reports, Journal Article
Publication date 1990
Journal information "Journal of analytical toxicology" - Vol. 14, no. 4, p. 231-4 (1990)
Peer reviewed yes
issn 0146-4760
Publication status Publié
Affiliation UCL
MESH Subject Adult ; Chromatography, High Pressure Liquid ; Diuron - metabolism - poisoning ; Female ; Gas Chromatography-Mass Spectrometry ; Humans ; Magnetic Resonance Spectroscopy ; Molecular Structure ; Reference Standards ; Spectrophotometry, Infrared
Links
Bibliographic reference Van Boven, Michel ; Laruelle, L. ; Daenens, P.. HPLC analysis of diuron and metabolites in blood and urine.. In: Journal of analytical toxicology, Vol. 14, no. 4, p. 231-4 (1990)
Permanent URL http://hdl.handle.net/2078.1/24755