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Spatial and temporal distribution of 7B2 in the pulmonary diffuse neuroendocrine system of the cat.

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Seldeslagh, K.A. [UCL] Lauweryns, J. M. [UCL]

The postnatal developmental profile of the presence of 7B2 was studied immunocytochemically in the pulmonary diffuse neuroendocrine system of the cat. Labelling was found in neuroepithelial bodies (NEB) but not in solitary neuroendocrine cells. The identity of NEB was confirmed on adjacent serial sections by the immunostaining for protein gene product 9.5, a pan-neuroendocrine marker. The first 3 weeks after birth 7B2 stained NEB were most abundant with a subsequent decline thereafter. The positive correlation between the variation of 7B2 immunoreactivity and number of NEB suggests an important role for 7B2 in NEB.

Document type Article de périodique (Journal article) – Comparative Study, Journal Article, Research Support, Non-U.S. Gov't
Access type Accès restreint
Publication date 1995
Journal information "Neuroscience letters" - Vol. 188, no. 2, p. 85-8 (1995)
Peer reviewed yes
issn 0304-3940
Publication status Publié
Affiliation UCL - MD/NOPS - Département de neurologie et de psychiatrie
MESH Subject Animals ; Animals, Newborn ; Cats ; Immunohistochemistry ; Lung - metabolism ; Nerve Tissue Proteins - metabolism ; Neuroendocrine Secretory Protein 7B2 ; Neurosecretory Systems - cytology - metabolism ; Pituitary Hormones - metabolism ; Thiolester Hydrolases - metabolism ; Time Factors ; Tissue Distribution ; Ubiquitin Thiolesterase
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Bibliographic reference Seldeslagh, K.A. ; Lauweryns, J. M.. Spatial and temporal distribution of 7B2 in the pulmonary diffuse neuroendocrine system of the cat.. In: Neuroscience letters, Vol. 188, no. 2, p. 85-8 (1995)
Permanent URL http://hdl.handle.net/2078.1/24431