User menu

Central nervous system regeneration is driven by microglia necroptosis and repopulation.

  1. Franklin Robin J. M., ffrench-Constant Charles, Regenerating CNS myelin — from mechanisms to experimental medicines, 10.1038/nrn.2017.136
  2. Frakes Ashley E., Ferraiuolo Laura, Haidet-Phillips Amanda M., Schmelzer Leah, Braun Lyndsey, Miranda Carlos J., Ladner Katherine J., Bevan Adam K., Foust Kevin D., Godbout Jonathan P., Popovich Phillip G., Guttridge Denis C., Kaspar Brian K., Microglia Induce Motor Neuron Death via the Classical NF-κB Pathway in Amyotrophic Lateral Sclerosis, 10.1016/j.neuron.2014.01.013
  3. Miron Veronique E, Boyd Amanda, Zhao Jing-Wei, Yuen Tracy J, Ruckh Julia M, Shadrach Jennifer L, van Wijngaarden Peter, Wagers Amy J, Williams Anna, Franklin Robin J M, ffrench-Constant Charles, M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination, 10.1038/nn.3469
  4. Kigerl K. A., Gensel J. C., Ankeny D. P., Alexander J. K., Donnelly D. J., Popovich P. G., Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord, 10.1523/jneurosci.3257-09.2009
  5. Wlodarczyk Agnieszka, Holtman Inge R, Krueger Martin, Yogev Nir, Bruttger Julia, Khorooshi Reza, Benmamar‐Badel Anouk, de Boer‐Bergsma Jelkje J, Martin Nellie A, Karram Khalad, Kramer Isabella, Boddeke Erik WGM, Waisman Ari, Eggen Bart JL, Owens Trevor, A novel microglial subset plays a key role in myelinogenesis in developing brain, 10.15252/embj.201696056
  6. Hagemeyer Nora, Hanft Klara-Maria, Akriditou Maria-Anna, Unger Nicole, Park Eun S., Stanley E. Richard, Staszewski Ori, Dimou Leda, Prinz Marco, Microglia contribute to normal myelinogenesis and to oligodendrocyte progenitor maintenance during adulthood, 10.1007/s00401-017-1747-1
  7. Keren-Shaul Hadas, Spinrad Amit, Weiner Assaf, Matcovitch-Natan Orit, Dvir-Szternfeld Raz, Ulland Tyler K., David Eyal, Baruch Kuti, Lara-Astaiso David, Toth Beata, Itzkovitz Shalev, Colonna Marco, Schwartz Michal, Amit Ido, A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease, 10.1016/j.cell.2017.05.018
  8. Krasemann Susanne, Madore Charlotte, Cialic Ron, Baufeld Caroline, Calcagno Narghes, El Fatimy Rachid, Beckers Lien, O’Loughlin Elaine, Xu Yang, Fanek Zain, Greco David J., Smith Scott T., Tweet George, Humulock Zachary, Zrzavy Tobias, Conde-Sanroman Patricia, Gacias Mar, Weng Zhiping, Chen Hao, Tjon Emily, Mazaheri Fargol, Hartmann Kristin, Madi Asaf, Ulrich Jason D., Glatzel Markus, Worthmann Anna, Heeren Joerg, Budnik Bogdan, Lemere Cynthia, Ikezu Tsuneya, Heppner Frank L., Litvak Vladimir, Holtzman David M., Lassmann Hans, Weiner Howard L., Ochando Jordi, Haass Christian, Butovsky Oleg, The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases, 10.1016/j.immuni.2017.08.008
  9. Lewis Nuruddeen D., Hill Jonathan D., Juchem Kathryn W., Stefanopoulos Dimitria E., Modis Louise K., RNA sequencing of microglia and monocyte-derived macrophages from mice with experimental autoimmune encephalomyelitis illustrates a changing phenotype with disease course, 10.1016/j.jneuroim.2014.09.014
  10. Mei Feng, Lehmann-Horn Klaus, Shen Yun-An A, Rankin Kelsey A, Stebbins Karin J, Lorrain Daniel S, Pekarek Kara, A Sagan Sharon, Xiao Lan, Teuscher Cory, von Büdingen H-Christian, Wess Jürgen, Lawrence J Josh, Green Ari J, Fancy Stephen PJ, Zamvil Scott S, Chan Jonah R, Accelerated remyelination during inflammatory demyelination prevents axonal loss and improves functional recovery, 10.7554/elife.18246
  11. Ofengeim Dimitry, Ito Yasushi, Najafov Ayaz, Zhang Yaoyang, Shan Bing, DeWitt Judy Park, Ye Juanying, Zhang Xumin, Chang Ansi, Vakifahmetoglu-Norberg Helin, Geng Jiefei, Py Benedicte, Zhou Wen, Amin Palak, Lima Jonilson Berlink, Qi Chunting, Yu Qiang, Trapp Bruce, Yuan Junying, Activation of Necroptosis in Multiple Sclerosis, 10.1016/j.celrep.2015.02.051
  12. Caccamo Antonella, Branca Caterina, Piras Ignazio S, Ferreira Eric, Huentelman Matthew J, Liang Winnie S, Readhead Ben, Dudley Joel T, Spangenberg Elizabeth E, Green Kim N, Belfiore Ramona, Winslow Wendy, Oddo Salvatore, Necroptosis activation in Alzheimer's disease, 10.1038/nn.4608
  13. Bruttger Julia, Karram Khalad, Wörtge Simone, Regen Tommy, Marini Federico, Hoppmann Nicola, Klein Matthias, Blank Thomas, Yona Simon, Wolf Yochai, Mack Matthias, Pinteaux Emmanuel, Müller Werner, Zipp Frauke, Binder Harald, Bopp Tobias, Prinz Marco, Jung Steffen, Waisman Ari, Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System, 10.1016/j.immuni.2015.06.012
  14. Elmore Monica R.P., Najafi Allison R., Koike Maya A., Dagher Nabil N., Spangenberg Elizabeth E., Rice Rachel A., Kitazawa Masashi, Matusow Bernice, Nguyen Hoa, West Brian L., Green Kim N., Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain, 10.1016/j.neuron.2014.02.040
  15. Huang Yubin, Xu Zhen, Xiong Shanshan, Sun Fangfang, Qin Guangrong, Hu Guanglei, Wang Jingjing, Zhao Lei, Liang Yu-Xiang, Wu Tianzhun, Lu Zhonghua, Humayun Mark S., So Kwok-Fai, Pan Yihang, Li Ningning, Yuan Ti-Fei, Rao Yanxia, Peng Bo, Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion, 10.1038/s41593-018-0090-8
  16. Hammond Timothy R., Dufort Connor, Dissing-Olesen Lasse, Giera Stefanie, Young Adam, Wysoker Alec, Walker Alec J., Gergits Frederick, Segel Michael, Nemesh James, Marsh Samuel E., Saunders Arpiar, Macosko Evan, Ginhoux Florent, Chen Jinmiao, Franklin Robin J.M., Piao Xianhua, McCarroll Steven A., Stevens Beth, Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes, 10.1016/j.immuni.2018.11.004
  17. Elmore Monica R. P., Hohsfield Lindsay A., Kramár Enikö A., Soreq Lilach, Lee Rafael J., Pham Stephanie T., Najafi Allison R., Spangenberg Elizabeth E., Wood Marcelo A., West Brian L., Green Kim N., Replacement of microglia in the aged brain reverses cognitive, synaptic, and neuronal deficits in mice : XXXX, 10.1111/acel.12832
  18. Krukowski Karen, Feng Xi, Paladini Maria Serena, Chou Austin, Sacramento Kristen, Grue Katherine, Riparip Lara-Kirstie, Jones Tamako, Campbell-Beachler Mary, Nelson Gregory, Rosi Susanna, Temporary microglia-depletion after cosmic radiation modifies phagocytic activity and prevents cognitive deficits, 10.1038/s41598-018-26039-7
  19. Rice Rachel A., Pham Jason, Lee Rafael J., Najafi Allison R., West Brian L., Green Kim N., Microglial repopulation resolves inflammation and promotes brain recovery after injury : RICE et al., 10.1002/glia.23135
  20. Rubino Stephen J., Mayo Lior, Wimmer Isabella, Siedler Victoria, Brunner Florian, Hametner Simon, Madi Asaf, Lanser Amanda, Moreira Thais, Donnelly Dustin, Cox Laura, Rezende Rafael Machado, Butovsky Oleg, Lassmann Hans, Weiner Howard L., Acute microglia ablation induces neurodegeneration in the somatosensory system, 10.1038/s41467-018-05929-4
  21. Oliveros, J. C. Venny. An interactive tool for comparing lists with Venn’s diagrams. http://bioinfogp.cnb.csic.es/tools/venny/index.html (2015).
Bibliographic reference Lloyd, Amy F ; Davies, Claire L ; Holloway, Rebecca K ; Labrak, Yasmine ; Ireland, Graeme ; et. al. Central nervous system regeneration is driven by microglia necroptosis and repopulation.. In: Nature neuroscience, Vol. 22, p. 1046-1052 (2019)
Permanent URL http://hdl.handle.net/2078.1/217066