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The artificial ovary: current status and future perspectives

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Andrade Amorim, Christiani [UCL] Shikanov, Ariella

Cryopreservation and transplantation of ovarian tissue has proved to be a promising technique to safeguard fertility in cancer patients. However, with some types of cancer, there is a risk of transmitting malignant cells present in the cryopreserved tissue, so transplantation after disease remission is not advisable. To restore fertility in these patients, some research teams have been developing a transplantable artificial ovary, whose main goal is to mimic the natural organ. It should be composed of a matrix that encapsulates and protects follicles, as well as ovarian cells, which are necessary for follicle survival and development. This article reviews progress made in the creation of a transplantable artificial ovary and discusses future trends for its development.

Document type Article de périodique (Journal article) – Synthèse de littérature
Access type Accès interdit
Publication date 2016
Language Anglais
Journal information "Future Oncology" - Vol. 12, no.20, p. 2323-2332 (2016)
Peer reviewed yes
Publisher Future Medicine Ltd. (London)
issn 1479-6694
e-issn 1744-8301
Publication status Publié
Affiliation UCL - SSS/IREC/GYNE - Pôle de Gynécologie
Links
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Bibliographic reference Andrade Amorim, Christiani ; Shikanov, Ariella. The artificial ovary: current status and future perspectives. In: Future Oncology, Vol. 12, no.20, p. 2323-2332 (2016)
Permanent URL http://hdl.handle.net/2078.1/182133